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2 similar compounds to monomer 50285397

Compile data set for download or QSAR
Wt: 280.7
BDBM50285417
Wt: 449.9
BDBM50285411

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50285417,50285411   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))
BDBM50285417
PNG
(CHEMBL4176866)
Show SMILES O\N=C(\CCC1CCCCC1)Nc1cccc(Cl)c1
Show InChI InChI=1S/C15H21ClN2O/c16-13-7-4-8-14(11-13)17-15(18-19)10-9-12-5-2-1-3-6-12/h4,7-8,11-12,19H,1-3,5-6,9-10H2,(H,17,18)
PDB
MMDB

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a<1.00E+3n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of IDO1 (unknown origin) assessed as reduction in kynurenine production by spectraphotometric assay


Eur J Med Chem 143: 656-669 (2018)


Article DOI: 10.1016/j.ejmech.2017.11.088
BindingDB Entry DOI: 10.7270/Q2GX4F22
More data for this
Ligand-Target Pair
Sodium/glucose cotransporter 2


(Homo sapiens (Human))
BDBM50285411
PNG
(CHEMBL4171400)
Show SMILES CCO\N=C\[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2ccc(OCC)cc2)c1
Show InChI InChI=1S/C23H28ClNO6/c1-3-29-17-8-5-14(6-9-17)11-16-12-15(7-10-18(16)24)23-22(28)21(27)20(26)19(31-23)13-25-30-4-2/h5-10,12-13,19-23,26-28H,3-4,11H2,1-2H3/b25-13+/t19-,20-,21+,22-,23+/m1/s1
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antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

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Article
PubMed
n/an/an/an/a 335n/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of human SGLT2 expressed in CHO cells assessed as reduction in [14C]AMG uptake after 1 hr by microbeta counting method


Eur J Med Chem 143: 611-620 (2018)


Article DOI: 10.1016/j.ejmech.2017.11.019
BindingDB Entry DOI: 10.7270/Q2MK6GFZ
More data for this
Ligand-Target Pair