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7 similar compounds to monomer 50309732

Compile data set for download or QSAR
Wt: 327.4
BDBM50309733
Wt: 341.4
BDBM50309734
Wt: 369.4
BDBM50309735
Wt: 383.5
BDBM50309736
Wt: 397.5
BDBM50309737
Wt: 331.3
BDBM50309738
Wt: 303.3
BDBM50309740

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50309733,50309734,50309735,50309736,50309737,50309738,50309740   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))
BDBM50309733
PNG
(CHEMBL599381 | phenyl 4-(heptyloxy)phenylcarbamate)
Show SMILES CCCCCCCOc1ccc(NC(=O)Oc2ccccc2)cc1
Show InChI InChI=1S/C20H25NO3/c1-2-3-4-5-9-16-23-18-14-12-17(13-15-18)21-20(22)24-19-10-7-6-8-11-19/h6-8,10-15H,2-5,9,16H2,1H3,(H,21,22)
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PubMed
n/an/a 8.60n/an/an/an/an/an/a



Bristol-Myers Squibb Research & Development

Curated by ChEMBL


Assay Description
Inhibition of human FAAH expressed in human H4 cells


Bioorg Med Chem Lett 20: 1272-7 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.080
BindingDB Entry DOI: 10.7270/Q2H41RKR
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))
BDBM50309734
PNG
(CHEMBL598572 | phenyl 4-(octyloxy)phenylcarbamate)
Show SMILES CCCCCCCCOc1ccc(NC(=O)Oc2ccccc2)cc1
Show InChI InChI=1S/C21H27NO3/c1-2-3-4-5-6-10-17-24-19-15-13-18(14-16-19)22-21(23)25-20-11-8-7-9-12-20/h7-9,11-16H,2-6,10,17H2,1H3,(H,22,23)
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n/an/a 5.40n/an/an/an/an/an/a



Bristol-Myers Squibb Research & Development

Curated by ChEMBL


Assay Description
Inhibition of human FAAH expressed in human H4 cells


Bioorg Med Chem Lett 20: 1272-7 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.080
BindingDB Entry DOI: 10.7270/Q2H41RKR
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))
BDBM50309735
PNG
(CHEMBL592771 | phenyl 4-(decyloxy)phenylcarbamate)
Show SMILES CCCCCCCCCCOc1ccc(NC(=O)Oc2ccccc2)cc1
Show InChI InChI=1S/C23H31NO3/c1-2-3-4-5-6-7-8-12-19-26-21-17-15-20(16-18-21)24-23(25)27-22-13-10-9-11-14-22/h9-11,13-18H,2-8,12,19H2,1H3,(H,24,25)
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n/an/a 1.40n/an/an/an/an/an/a



Bristol-Myers Squibb Research & Development

Curated by ChEMBL


Assay Description
Inhibition of human FAAH expressed in human H4 cells


Bioorg Med Chem Lett 20: 1272-7 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.080
BindingDB Entry DOI: 10.7270/Q2H41RKR
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))
BDBM50309740
PNG
(4-fluorophenyl 4-butoxyphenylcarbamate | CHEMBL591...)
Show SMILES CCCCOc1ccc(NC(=O)Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C17H18FNO3/c1-2-3-12-21-15-10-6-14(7-11-15)19-17(20)22-16-8-4-13(18)5-9-16/h4-11H,2-3,12H2,1H3,(H,19,20)
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n/an/a 120n/an/an/an/an/an/a



Bristol-Myers Squibb Research & Development

Curated by ChEMBL


Assay Description
Inhibition of human FAAH expressed in human H4 cells


Bioorg Med Chem Lett 20: 1272-7 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.080
BindingDB Entry DOI: 10.7270/Q2H41RKR
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))
BDBM50309737
PNG
(CHEMBL592772 | phenyl 4-(dodecyloxy)phenylcarbamat...)
Show SMILES CCCCCCCCCCCCOc1ccc(NC(=O)Oc2ccccc2)cc1
Show InChI InChI=1S/C25H35NO3/c1-2-3-4-5-6-7-8-9-10-14-21-28-23-19-17-22(18-20-23)26-25(27)29-24-15-12-11-13-16-24/h11-13,15-20H,2-10,14,21H2,1H3,(H,26,27)
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n/an/a 1.80n/an/an/an/an/an/a



Bristol-Myers Squibb Research & Development

Curated by ChEMBL


Assay Description
Inhibition of human FAAH expressed in human H4 cells


Bioorg Med Chem Lett 20: 1272-7 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.080
BindingDB Entry DOI: 10.7270/Q2H41RKR
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))
BDBM50309738
PNG
(2-fluorophenyl 4-(hexyloxy)phenylcarbamate | CHEMB...)
Show SMILES CCCCCCOc1ccc(NC(=O)Oc2ccccc2F)cc1
Show InChI InChI=1S/C19H22FNO3/c1-2-3-4-7-14-23-16-12-10-15(11-13-16)21-19(22)24-18-9-6-5-8-17(18)20/h5-6,8-13H,2-4,7,14H2,1H3,(H,21,22)
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n/an/a 710n/an/an/an/an/an/a



Bristol-Myers Squibb Research & Development

Curated by ChEMBL


Assay Description
Inhibition of human FAAH expressed in human H4 cells


Bioorg Med Chem Lett 20: 1272-7 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.080
BindingDB Entry DOI: 10.7270/Q2H41RKR
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))
BDBM50309736
PNG
(CHEMBL597923 | phenyl 4-(undecyloxy)phenylcarbamat...)
Show SMILES CCCCCCCCCCCOc1ccc(NC(=O)Oc2ccccc2)cc1
Show InChI InChI=1S/C24H33NO3/c1-2-3-4-5-6-7-8-9-13-20-27-22-18-16-21(17-19-22)25-24(26)28-23-14-11-10-12-15-23/h10-12,14-19H,2-9,13,20H2,1H3,(H,25,26)
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n/an/a 1n/an/an/an/an/an/a



Bristol-Myers Squibb Research & Development

Curated by ChEMBL


Assay Description
Inhibition of human FAAH expressed in human H4 cells


Bioorg Med Chem Lett 20: 1272-7 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.080
BindingDB Entry DOI: 10.7270/Q2H41RKR
More data for this
Ligand-Target Pair