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12 similar compounds to monomer 50370787

Compile data set for download or QSAR
Wt: 369.3
BDBM50370781
Wt: 410.4
BDBM50370782
Wt: 343.7
BDBM50370784
Wt: 351.3
BDBM50370786
Wt: 343.7
BDBM50370788
Wt: 343.7
BDBM50370789
Wt: 323.3
BDBM50370790
Wt: 309.3
BDBM50370791
Wt: 339.3
BDBM50370792
Wt: 334.3
BDBM50370793
Wt: 295.2
BDBM50370803
Wt: 295.2
BDBM50370804

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50370781,50370782,50370784,50370786,50370788,50370789,50370790,50370791,50370792,50370793,50370803,50370804   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Egl nine homolog 1


(Homo sapiens (Human))
BDBM50370781
PNG
(CHEMBL374147)
Show SMILES COc1cc(COCc2ccc(nc2)-n2cc(cn2)C(O)=O)cc(OC)c1
Show InChI InChI=1S/C19H19N3O5/c1-25-16-5-14(6-17(7-16)26-2)12-27-11-13-3-4-18(20-8-13)22-10-15(9-21-22)19(23)24/h3-10H,11-12H2,1-2H3,(H,23,24)
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n/an/a 2.80E+3n/an/an/an/an/an/a



Procter and Gamble Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of human EGLN1


Bioorg Med Chem Lett 16: 5687-90 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.017
BindingDB Entry DOI: 10.7270/Q25Q4WXS
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM50370782
PNG
(CHEMBL222115)
Show SMILES OC(=O)c1cnn(c1)-c1ccc(COCc2ccc(cc2)-c2ccccc2C#N)cn1
Show InChI InChI=1S/C24H18N4O3/c25-11-20-3-1-2-4-22(20)19-8-5-17(6-9-19)15-31-16-18-7-10-23(26-12-18)28-14-21(13-27-28)24(29)30/h1-10,12-14H,15-16H2,(H,29,30)
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n/an/a 190n/an/an/an/an/an/a



Procter and Gamble Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of human EGLN1


Bioorg Med Chem Lett 16: 5687-90 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.017
BindingDB Entry DOI: 10.7270/Q25Q4WXS
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM50370784
PNG
(CHEMBL221012)
Show SMILES OC(=O)c1cnn(c1)-c1ccc(COCc2ccc(Cl)cc2)cn1
Show InChI InChI=1S/C17H14ClN3O3/c18-15-4-1-12(2-5-15)10-24-11-13-3-6-16(19-7-13)21-9-14(8-20-21)17(22)23/h1-9H,10-11H2,(H,22,23)
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n/an/a 580n/an/an/an/an/an/a



Procter and Gamble Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of human EGLN1


Bioorg Med Chem Lett 16: 5687-90 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.017
BindingDB Entry DOI: 10.7270/Q25Q4WXS
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM50370786
PNG
(CHEMBL221241)
Show SMILES CC(C)c1ccc(COCc2ccc(nc2)-n2cc(cn2)C(O)=O)cc1
Show InChI InChI=1S/C20H21N3O3/c1-14(2)17-6-3-15(4-7-17)12-26-13-16-5-8-19(21-9-16)23-11-18(10-22-23)20(24)25/h3-11,14H,12-13H2,1-2H3,(H,24,25)
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n/an/a 1.70E+3n/an/an/an/an/an/a



Procter and Gamble Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of human EGLN1


Bioorg Med Chem Lett 16: 5687-90 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.017
BindingDB Entry DOI: 10.7270/Q25Q4WXS
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM50370788
PNG
(CHEMBL375008)
Show SMILES OC(=O)c1cnn(c1)-c1ccc(COCc2ccccc2Cl)cn1
Show InChI InChI=1S/C17H14ClN3O3/c18-15-4-2-1-3-13(15)11-24-10-12-5-6-16(19-7-12)21-9-14(8-20-21)17(22)23/h1-9H,10-11H2,(H,22,23)
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n/an/a 2.40E+3n/an/an/an/an/an/a



Procter and Gamble Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of human EGLN1


Bioorg Med Chem Lett 16: 5687-90 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.017
BindingDB Entry DOI: 10.7270/Q25Q4WXS
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM50370804
PNG
(CHEMBL218233)
Show SMILES COc1cccc(c1)-c1ccc(nc1)-n1cc(cn1)C(O)=O
Show InChI InChI=1S/C16H13N3O3/c1-22-14-4-2-3-11(7-14)12-5-6-15(17-8-12)19-10-13(9-18-19)16(20)21/h2-10H,1H3,(H,20,21)
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n/an/a 1.00E+4n/an/an/an/an/an/a



Procter and Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of EGLN1


Bioorg Med Chem Lett 16: 5616-20 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.026
BindingDB Entry DOI: 10.7270/Q21Z4579
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM50370790
PNG
(CHEMBL218424)
Show SMILES Cc1cccc(COCc2ccc(nc2)-n2cc(cn2)C(O)=O)c1
Show InChI InChI=1S/C18H17N3O3/c1-13-3-2-4-14(7-13)11-24-12-15-5-6-17(19-8-15)21-10-16(9-20-21)18(22)23/h2-10H,11-12H2,1H3,(H,22,23)
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n/an/a 2.10E+3n/an/an/an/an/an/a



Procter and Gamble Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of human EGLN1


Bioorg Med Chem Lett 16: 5687-90 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.017
BindingDB Entry DOI: 10.7270/Q25Q4WXS
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM50370791
PNG
(CHEMBL221189)
Show SMILES OC(=O)c1cnn(c1)-c1ccc(COCc2ccccc2)cn1
Show InChI InChI=1S/C17H15N3O3/c21-17(22)15-9-19-20(10-15)16-7-6-14(8-18-16)12-23-11-13-4-2-1-3-5-13/h1-10H,11-12H2,(H,21,22)
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n/an/a 2.70E+3n/an/an/an/an/an/a



Procter and Gamble Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of human EGLN1


Bioorg Med Chem Lett 16: 5687-90 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.017
BindingDB Entry DOI: 10.7270/Q25Q4WXS
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM50370792
PNG
(CHEMBL222114)
Show SMILES COc1ccc(COCc2ccc(nc2)-n2cc(cn2)C(O)=O)cc1
Show InChI InChI=1S/C18H17N3O4/c1-24-16-5-2-13(3-6-16)11-25-12-14-4-7-17(19-8-14)21-10-15(9-20-21)18(22)23/h2-10H,11-12H2,1H3,(H,22,23)
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n/an/a 2.40E+3n/an/an/an/an/an/a



Procter and Gamble Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of human EGLN1


Bioorg Med Chem Lett 16: 5687-90 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.017
BindingDB Entry DOI: 10.7270/Q25Q4WXS
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM50370793
PNG
(CHEMBL218070)
Show SMILES OC(=O)c1cnn(c1)-c1ccc(COCc2ccc(cc2)C#N)cn1
Show InChI InChI=1S/C18H14N4O3/c19-7-13-1-3-14(4-2-13)11-25-12-15-5-6-17(20-8-15)22-10-16(9-21-22)18(23)24/h1-6,8-10H,11-12H2,(H,23,24)
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n/an/a 1.60E+3n/an/an/an/an/an/a



Procter and Gamble Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of human EGLN1


Bioorg Med Chem Lett 16: 5687-90 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.017
BindingDB Entry DOI: 10.7270/Q25Q4WXS
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM50370803
PNG
(CHEMBL222010)
Show SMILES COc1ccc(cc1)-c1ccc(nc1)-n1cc(cn1)C(O)=O
Show InChI InChI=1S/C16H13N3O3/c1-22-14-5-2-11(3-6-14)12-4-7-15(17-8-12)19-10-13(9-18-19)16(20)21/h2-10H,1H3,(H,20,21)
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n/an/a 7.30E+3n/an/an/an/an/an/a



Procter and Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of EGLN1


Bioorg Med Chem Lett 16: 5616-20 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.026
BindingDB Entry DOI: 10.7270/Q21Z4579
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))
BDBM50370789
PNG
(CHEMBL221013)
Show SMILES OC(=O)c1cnn(c1)-c1ccc(COCc2cccc(Cl)c2)cn1
Show InChI InChI=1S/C17H14ClN3O3/c18-15-3-1-2-12(6-15)10-24-11-13-4-5-16(19-7-13)21-9-14(8-20-21)17(22)23/h1-9H,10-11H2,(H,22,23)
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n/an/a 1.70E+3n/an/an/an/an/an/a



Procter and Gamble Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of human EGLN1


Bioorg Med Chem Lett 16: 5687-90 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.017
BindingDB Entry DOI: 10.7270/Q25Q4WXS
More data for this
Ligand-Target Pair