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2 similar compounds to monomer 50001901

Compile data set for download or QSAR
Wt: 245.1
BDBM50394929
Wt: 231.1
BDBM50394930
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50394929,50394930   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50394929
PNG
(CHEMBL2165673)
Show SMILES CN1CCN(CC1)c1cccc(Cl)c1Cl
Show InChI InChI=1S/C11H14Cl2N2/c1-14-5-7-15(8-6-14)10-4-2-3-9(12)11(10)13/h2-4H,5-8H2,1H3
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Article
PubMed
45.9n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL


Assay Description
Displacement of [125I]IABN from human D2L receptor expressed in HEK293 cells after 60 mins by gamma counting analysis


J Med Chem 55: 6689-99 (2012)


Article DOI: 10.1021/jm300482h
BindingDB Entry DOI: 10.7270/Q2Q81F6B
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50394929
PNG
(CHEMBL2165673)
Show SMILES CN1CCN(CC1)c1cccc(Cl)c1Cl
Show InChI InChI=1S/C11H14Cl2N2/c1-14-5-7-15(8-6-14)10-4-2-3-9(12)11(10)13/h2-4H,5-8H2,1H3
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
54.6n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL


Assay Description
Displacement of [125I]IABN from human D3 receptor expressed in HEK293 cells after 60 mins by gamma counting analysis


J Med Chem 55: 6689-99 (2012)


Article DOI: 10.1021/jm300482h
BindingDB Entry DOI: 10.7270/Q2Q81F6B
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50394930
PNG
(CHEMBL1424807)
Show SMILES Clc1cccc(N2CCNCC2)c1Cl
Show InChI InChI=1S/C10H12Cl2N2/c11-8-2-1-3-9(10(8)12)14-6-4-13-5-7-14/h1-3,13H,4-7H2
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Article
PubMed
137n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL


Assay Description
Displacement of [125I]IABN from human D2L receptor expressed in HEK293 cells after 60 mins by gamma counting analysis


J Med Chem 55: 6689-99 (2012)


Article DOI: 10.1021/jm300482h
BindingDB Entry DOI: 10.7270/Q2Q81F6B
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50394930
PNG
(CHEMBL1424807)
Show SMILES Clc1cccc(N2CCNCC2)c1Cl
Show InChI InChI=1S/C10H12Cl2N2/c11-8-2-1-3-9(10(8)12)14-6-4-13-5-7-14/h1-3,13H,4-7H2
UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
197n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL


Assay Description
Displacement of [125I]IABN from human D3 receptor expressed in HEK293 cells after 60 mins by gamma counting analysis


J Med Chem 55: 6689-99 (2012)


Article DOI: 10.1021/jm300482h
BindingDB Entry DOI: 10.7270/Q2Q81F6B
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50394930
PNG
(CHEMBL1424807)
Show SMILES Clc1cccc(N2CCNCC2)c1Cl
Show InChI InChI=1S/C10H12Cl2N2/c11-8-2-1-3-9(10(8)12)14-6-4-13-5-7-14/h1-3,13H,4-7H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.16E+3n/an/an/an/an/an/an/an/a



Monash University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from human D2L receptor expressed in FlpIn CHO cell membrane after 3 hrs by liquid scintillation counting analysis


J Med Chem 57: 4924-39 (2014)


Article DOI: 10.1021/jm500457x
BindingDB Entry DOI: 10.7270/Q29Z96FS
More data for this
Ligand-Target Pair