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9 similar compounds to monomer 50452980

Compile data set for download or QSAR
Wt: 395.5
BDBM50452982
Wt: 395.5
BDBM50452983
Wt: 395.5
BDBM50452984
Wt: 423.5
BDBM50452985
Wt: 423.5
BDBM50452986
Wt: 395.5
BDBM50452987
Wt: 367.4
BDBM50452988
Wt: 367.4
BDBM50452989
Wt: 367.4
BDBM50452981

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50452982,50452983,50452984,50452985,50452986,50452987,50452988,50452989,50452981   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50452985
PNG
(CHEMBL2114234)
Show SMILES CCCCCCN1CCC[C@@H]1CNC(=O)c1cc(cc2C[C@H](C)Oc12)S(N)(=O)=O
Show InChI InChI=1S/C21H33N3O4S/c1-3-4-5-6-9-24-10-7-8-17(24)14-23-21(25)19-13-18(29(22,26)27)12-16-11-15(2)28-20(16)19/h12-13,15,17H,3-11,14H2,1-2H3,(H,23,25)(H2,22,26,27)/t15-,17+/m0/s1
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6.70n/an/an/an/an/an/an/an/a



Yoshitomi Pharmaceutical Industries Ltd.

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using as [3H]-spiperone radioligand.


J Med Chem 34: 261-7 (1991)


Article DOI: 10.1021/jm00105a041
BindingDB Entry DOI: 10.7270/Q2W959SQ
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50452983
PNG
(CHEMBL2114236)
Show SMILES CCCCN1CCC[C@@H]1CNC(=O)c1cc(cc2C[C@H](C)Oc12)S(N)(=O)=O
Show InChI InChI=1S/C19H29N3O4S/c1-3-4-7-22-8-5-6-15(22)12-21-19(23)17-11-16(27(20,24)25)10-14-9-13(2)26-18(14)17/h10-11,13,15H,3-9,12H2,1-2H3,(H,21,23)(H2,20,24,25)/t13-,15+/m0/s1
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9.40n/an/an/an/an/an/an/an/a



Yoshitomi Pharmaceutical Industries Ltd.

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using as [3H]-spiperone radioligand.


J Med Chem 34: 261-7 (1991)


Article DOI: 10.1021/jm00105a041
BindingDB Entry DOI: 10.7270/Q2W959SQ
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50452981
PNG
(CHEMBL2115231)
Show SMILES CCN1CCC[C@H]1CNC(=O)c1cc(cc2C[C@H](C)Oc12)S(N)(=O)=O
Show InChI InChI=1S/C17H25N3O4S/c1-3-20-6-4-5-13(20)10-19-17(21)15-9-14(25(18,22)23)8-12-7-11(2)24-16(12)15/h8-9,11,13H,3-7,10H2,1-2H3,(H,19,21)(H2,18,22,23)/t11-,13-/m0/s1
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9.60n/an/an/an/an/an/an/an/a



Yoshitomi Pharmaceutical Industries Ltd.

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using as [3H]-spiperone radioligand.


J Med Chem 34: 261-7 (1991)


Article DOI: 10.1021/jm00105a041
BindingDB Entry DOI: 10.7270/Q2W959SQ
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50452984
PNG
(CHEMBL2114235)
Show SMILES CCCCN1CCC[C@@H]1CNC(=O)c1cc(cc2C[C@@H](C)Oc12)S(N)(=O)=O
Show InChI InChI=1S/C19H29N3O4S/c1-3-4-7-22-8-5-6-15(22)12-21-19(23)17-11-16(27(20,24)25)10-14-9-13(2)26-18(14)17/h10-11,13,15H,3-9,12H2,1-2H3,(H,21,23)(H2,20,24,25)/t13-,15-/m1/s1
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23n/an/an/an/an/an/an/an/a



Yoshitomi Pharmaceutical Industries Ltd.

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using as [3H]-spiperone radioligand.


J Med Chem 34: 261-7 (1991)


Article DOI: 10.1021/jm00105a041
BindingDB Entry DOI: 10.7270/Q2W959SQ
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50452982
PNG
(CHEMBL2115229)
Show SMILES CCCCN1CCC[C@H]1CNC(=O)c1cc(cc2C[C@H](C)Oc12)S(N)(=O)=O
Show InChI InChI=1S/C19H29N3O4S/c1-3-4-7-22-8-5-6-15(22)12-21-19(23)17-11-16(27(20,24)25)10-14-9-13(2)26-18(14)17/h10-11,13,15H,3-9,12H2,1-2H3,(H,21,23)(H2,20,24,25)/t13-,15-/m0/s1
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95n/an/an/an/an/an/an/an/a



Yoshitomi Pharmaceutical Industries Ltd.

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using as [3H]-spiperone radioligand.


J Med Chem 34: 261-7 (1991)


Article DOI: 10.1021/jm00105a041
BindingDB Entry DOI: 10.7270/Q2W959SQ
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50452987
PNG
(CHEMBL2115228)
Show SMILES CCCCN1CCC[C@H]1CNC(=O)c1cc(cc2C[C@@H](C)Oc12)S(N)(=O)=O
Show InChI InChI=1S/C19H29N3O4S/c1-3-4-7-22-8-5-6-15(22)12-21-19(23)17-11-16(27(20,24)25)10-14-9-13(2)26-18(14)17/h10-11,13,15H,3-9,12H2,1-2H3,(H,21,23)(H2,20,24,25)/t13-,15+/m1/s1
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210n/an/an/an/an/an/an/an/a



Yoshitomi Pharmaceutical Industries Ltd.

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using as [3H]-spiperone radioligand.


J Med Chem 34: 261-7 (1991)


Article DOI: 10.1021/jm00105a041
BindingDB Entry DOI: 10.7270/Q2W959SQ
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50452988
PNG
(CHEMBL2114238)
Show SMILES CCN1CCC[C@@H]1CNC(=O)c1cc(cc2C[C@H](C)Oc12)S(N)(=O)=O
Show InChI InChI=1S/C17H25N3O4S/c1-3-20-6-4-5-13(20)10-19-17(21)15-9-14(25(18,22)23)8-12-7-11(2)24-16(12)15/h8-9,11,13H,3-7,10H2,1-2H3,(H,19,21)(H2,18,22,23)/t11-,13+/m0/s1
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400n/an/an/an/an/an/an/an/a



Yoshitomi Pharmaceutical Industries Ltd.

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using as [3H]-spiperone radioligand.


J Med Chem 34: 261-7 (1991)


Article DOI: 10.1021/jm00105a041
BindingDB Entry DOI: 10.7270/Q2W959SQ
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50452986
PNG
(CHEMBL2115227)
Show SMILES CCCCCCN1CCC[C@H]1CNC(=O)c1cc(cc2C[C@H](C)Oc12)S(N)(=O)=O
Show InChI InChI=1S/C21H33N3O4S/c1-3-4-5-6-9-24-10-7-8-17(24)14-23-21(25)19-13-18(29(22,26)27)12-16-11-15(2)28-20(16)19/h12-13,15,17H,3-11,14H2,1-2H3,(H,23,25)(H2,22,26,27)/t15-,17-/m0/s1
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630n/an/an/an/an/an/an/an/a



Yoshitomi Pharmaceutical Industries Ltd.

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using as [3H]-spiperone radioligand.


J Med Chem 34: 261-7 (1991)


Article DOI: 10.1021/jm00105a041
BindingDB Entry DOI: 10.7270/Q2W959SQ
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50452989
PNG
(CHEMBL2114239)
Show SMILES CCN1CCC[C@@H]1CNC(=O)c1cc(cc2C[C@@H](C)Oc12)S(N)(=O)=O
Show InChI InChI=1S/C17H25N3O4S/c1-3-20-6-4-5-13(20)10-19-17(21)15-9-14(25(18,22)23)8-12-7-11(2)24-16(12)15/h8-9,11,13H,3-7,10H2,1-2H3,(H,19,21)(H2,18,22,23)/t11-,13-/m1/s1
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650n/an/an/an/an/an/an/an/a



Yoshitomi Pharmaceutical Industries Ltd.

Curated by ChEMBL


Assay Description
Binding affinity towards dopamine receptor D2 using as [3H]-spiperone radioligand.


J Med Chem 34: 261-7 (1991)


Article DOI: 10.1021/jm00105a041
BindingDB Entry DOI: 10.7270/Q2W959SQ
More data for this
Ligand-Target Pair