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1 similar compounds to monomer 50453186

Compile data set for download or QSAR
Wt: 335.4
BDBM50453182

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50453182   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50453182
PNG
(CHEMBL2114061)
Show SMILES CN1CC2C[C@H](OC(=O)C(C)(c3ccccc3)c3ccccc3)C1C2
Show InChI InChI=1S/C22H25NO2/c1-22(17-9-5-3-6-10-17,18-11-7-4-8-12-18)21(24)25-20-14-16-13-19(20)23(2)15-16/h3-12,16,19-20H,13-15H2,1-2H3/t16?,19?,20-/m0/s1
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KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.20n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-QNB binding to Muscarinic acetylcholine receptor M1 transfected with CHO cell


J Med Chem 35: 2184-91 (1992)


Article DOI: 10.1021/jm00090a006
BindingDB Entry DOI: 10.7270/Q2B27T74
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(RAT)
BDBM50453182
PNG
(CHEMBL2114061)
Show SMILES CN1CC2C[C@H](OC(=O)C(C)(c3ccccc3)c3ccccc3)C1C2
Show InChI InChI=1S/C22H25NO2/c1-22(17-9-5-3-6-10-17,18-11-7-4-8-12-18)21(24)25-20-14-16-13-19(20)23(2)15-16/h3-12,16,19-20H,13-15H2,1-2H3/t16?,19?,20-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
4n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]-QNB binding to Muscarinic acetylcholine receptor M3 transfected with CHO cell


J Med Chem 35: 2184-91 (1992)


Article DOI: 10.1021/jm00090a006
BindingDB Entry DOI: 10.7270/Q2B27T74
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50453182
PNG
(CHEMBL2114061)
Show SMILES CN1CC2C[C@H](OC(=O)C(C)(c3ccccc3)c3ccccc3)C1C2
Show InChI InChI=1S/C22H25NO2/c1-22(17-9-5-3-6-10-17,18-11-7-4-8-12-18)21(24)25-20-14-16-13-19(20)23(2)15-16/h3-12,16,19-20H,13-15H2,1-2H3/t16?,19?,20-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
6.10n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]QNB binding to muscarinic receptor of rat heart membrane preparation.


J Med Chem 35: 2184-91 (1992)


Article DOI: 10.1021/jm00090a006
BindingDB Entry DOI: 10.7270/Q2B27T74
More data for this
Ligand-Target Pair