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28 similar compounds to monomer 50367879

Compile data set for download or QSAR
Wt: 405.4
BDBM66979
Purchase
Wt: 362.4
BDBM50452268
Wt: 318.3
BDBM50405267
Wt: 348.3
BDBM50011192
Wt: 348.3
BDBM50011359
Wt: 376.4
BDBM50017129
Purchase
Wt: 334.3
BDBM50021266
Wt: 362.4
BDBM50021267
Wt: 376.4
BDBM50021268
Wt: 348.3
BDBM50021269
Wt: 320.3
BDBM50021270
Wt: 334.3
BDBM50011364
Wt: 348.3
BDBM50021129
Wt: 347.4
BDBM50078398
Wt: 574.6
BDBM50125258
Displayed 1 to 15 (of 26 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 48 hits for monomerid = 66979,50452268,50405267,50011192,50011359,50017129,50021266,50021267,50021268,50021269,50021270,50011364,50021129,50078398,50125258   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Renin


(Homo sapiens (Human))
BDBM50021129
PNG
(1-[2-(1-Carboxy-3-phenyl-propylamino)-propionyl]-p...)
Show SMILES C[C@H](NC(CCc1ccccc1)C(O)=O)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C18H24N2O5/c1-12(16(21)20-11-5-8-15(20)18(24)25)19-14(17(22)23)10-9-13-6-3-2-4-7-13/h2-4,6-7,12,14-15,19H,5,8-11H2,1H3,(H,22,23)(H,24,25)/t12-,14?,15-/m0/s1
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1.20n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Antihypertensive activity against human renin


J Med Chem 24: 355-61 (1981)


Article DOI: 10.1021/jm00136a001
BindingDB Entry DOI: 10.7270/Q2PC32XP
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50125258
PNG
((S)-1-[(S)-6-Amino-2-((S)-2-{[(S)-1-((S)-2-amino-3...)
Show SMILES NCCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccccc1)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C28H42N6O7/c29-13-5-4-10-20(27(39)34-15-7-12-23(34)28(40)41)31-24(36)21(17-35)32-25(37)22-11-6-14-33(22)26(38)19(30)16-18-8-2-1-3-9-18/h1-3,8-9,19-23,35H,4-7,10-17,29-30H2,(H,31,36)(H,32,37)(H,40,41)/t19-,20-,21-,22-,23-/m0/s1
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7.50E+3n/an/an/an/an/an/an/an/a



University of North Carolina at Wilmington

Curated by ChEMBL


Assay Description
Binding affinity towards non-selective opiate receptor


Bioorg Med Chem Lett 13: 1029-31 (2003)


Article DOI: 10.1016/s0960-894x(03)00082-9
BindingDB Entry DOI: 10.7270/Q2FB53GH
More data for this
Ligand-Target Pair
Solute carrier family 15 member 1


(Rattus norvegicus)
BDBM50017129
PNG
((S)-1-((S)-2-((R)-1-ethoxy-1-oxo-4-phenylbutan-2-y...)
Show SMILES CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1
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4.30E+6n/an/an/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of D-Phe-L-Gln uptake in Xenopus laevis oocytes


Biochim Biophys Acta 1373: 277-81 (1998)


Article DOI: 10.1016/s0005-2736(98)00093-5
BindingDB Entry DOI: 10.7270/Q2C24XPC
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Oryctolagus cuniculus)
BDBM50011364
PNG
(1-[2-(1-Carboxy-3-phenyl-propylamino)-acetyl]-pyrr...)
Show SMILES OC(=O)[C@H](CCc1ccccc1)NCC(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C17H22N2O5/c20-15(19-10-4-7-14(19)17(23)24)11-18-13(16(21)22)9-8-12-5-2-1-3-6-12/h1-3,5-6,13-14,18H,4,7-11H2,(H,21,22)(H,23,24)/t13-,14-/m0/s1
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n/an/a 230n/an/an/an/an/an/a



Institut de Chimie des Substances Naturelles

Curated by ChEMBL


Assay Description
In vitro activity against angiotensin I converting enzyme especially against Hip-His-Leu residues


J Med Chem 34: 663-9 (1991)


Article DOI: 10.1021/jm00106a030
BindingDB Entry DOI: 10.7270/Q21V5FKF
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Oryctolagus cuniculus)
BDBM50011359
PNG
(1-[2-(1-Carboxy-3-phenyl-propylamino)-propionyl]-p...)
Show SMILES C[C@@H](NC(CCc1ccccc1)C(O)=O)C(=O)N1CCCC1C(O)=O
Show InChI InChI=1S/C18H24N2O5/c1-12(16(21)20-11-5-8-15(20)18(24)25)19-14(17(22)23)10-9-13-6-3-2-4-7-13/h2-4,6-7,12,14-15,19H,5,8-11H2,1H3,(H,22,23)(H,24,25)/t12-,14?,15?/m1/s1
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n/an/a 2.50E+3n/an/an/an/an/an/a



Institut de Chimie des Substances Naturelles

Curated by ChEMBL


Assay Description
In vitro activity against angiotensin I converting enzyme especially against Hip-His-Leu residues


J Med Chem 34: 663-9 (1991)


Article DOI: 10.1021/jm00106a030
BindingDB Entry DOI: 10.7270/Q21V5FKF
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Oryctolagus cuniculus)
BDBM50017129
PNG
((S)-1-((S)-2-((R)-1-ethoxy-1-oxo-4-phenylbutan-2-y...)
Show SMILES CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1
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n/an/a 8.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against rabbit lung Angiotensin I converting enzyme at pH 8.3


J Med Chem 28: 57-66 (1985)


Article DOI: 10.1021/jm00379a013
BindingDB Entry DOI: 10.7270/Q2M90975
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Oryctolagus cuniculus)
BDBM50021129
PNG
(1-[2-(1-Carboxy-3-phenyl-propylamino)-propionyl]-p...)
Show SMILES C[C@H](NC(CCc1ccccc1)C(O)=O)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C18H24N2O5/c1-12(16(21)20-11-5-8-15(20)18(24)25)19-14(17(22)23)10-9-13-6-3-2-4-7-13/h2-4,6-7,12,14-15,19H,5,8-11H2,1H3,(H,22,23)(H,24,25)/t12-,14?,15-/m0/s1
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n/an/a 4.5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Angiotensin I converting enzyme


J Med Chem 28: 1511-6 (1985)


Article DOI: 10.1021/jm00148a023
BindingDB Entry DOI: 10.7270/Q2BR8SRQ
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Homo sapiens (Human))
BDBM50021270
PNG
(2-(1-Carboxymethyl-2-oxo-pyrrolidin-3-ylamino)-4-p...)
Show SMILES OC(=O)CN1CCC(NC(CCc2ccccc2)C(O)=O)C1=O
Show InChI InChI=1S/C16H20N2O5/c19-14(20)10-18-9-8-12(15(18)21)17-13(16(22)23)7-6-11-4-2-1-3-5-11/h1-5,12-13,17H,6-10H2,(H,19,20)(H,22,23)
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n/an/a 1.20E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration (isomer B) against Angiotensin I converting enzyme


J Med Chem 29: 251-60 (1986)


Article DOI: 10.1021/jm00152a014
BindingDB Entry DOI: 10.7270/Q2J67HH7
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Homo sapiens (Human))
BDBM50452268
PNG
(CHEMBL2114219)
Show SMILES OC(=O)CN1CCCCC[C@H](N[C@@H](CCc2ccccc2)C(O)=O)C1=O
Show InChI InChI=1S/C19H26N2O5/c22-17(23)13-21-12-6-2-5-9-15(18(21)24)20-16(19(25)26)11-10-14-7-3-1-4-8-14/h1,3-4,7-8,15-16,20H,2,5-6,9-13H2,(H,22,23)(H,25,26)/t15-,16-/m0/s1
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n/an/a 2n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration (isomer B) against Angiotensin I converting enzyme


J Med Chem 29: 251-60 (1986)


Article DOI: 10.1021/jm00152a014
BindingDB Entry DOI: 10.7270/Q2J67HH7
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Homo sapiens (Human))
BDBM50021266
PNG
(2-(1-Carboxymethyl-2-oxo-piperidin-3-ylamino)-4-ph...)
Show SMILES OC(=O)CN1CCCC(NC(CCc2ccccc2)C(O)=O)C1=O
Show InChI InChI=1S/C17H22N2O5/c20-15(21)11-19-10-4-7-13(16(19)22)18-14(17(23)24)9-8-12-5-2-1-3-6-12/h1-3,5-6,13-14,18H,4,7-11H2,(H,20,21)(H,23,24)
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n/an/a 430n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration (isomer A) against Angiotensin I converting enzyme


J Med Chem 29: 251-60 (1986)


Article DOI: 10.1021/jm00152a014
BindingDB Entry DOI: 10.7270/Q2J67HH7
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Oryctolagus cuniculus)
BDBM50017129
PNG
((S)-1-((S)-2-((R)-1-ethoxy-1-oxo-4-phenylbutan-2-y...)
Show SMILES CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1
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n/an/a 800n/an/an/an/an/an/a



Rorer Central Research

Curated by ChEMBL


Assay Description
In vitro inhibition of Angiotensin I converting enzyme in rabbit lung


J Med Chem 33: 1606-15 (1990)


Article DOI: 10.1021/jm00168a013
BindingDB Entry DOI: 10.7270/Q2CF9QPK
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Oryctolagus cuniculus)
BDBM50017129
PNG
((S)-1-((S)-2-((R)-1-ethoxy-1-oxo-4-phenylbutan-2-y...)
Show SMILES CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1
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n/an/a 2n/an/an/an/an/an/a



CIBA-GEIGY Corporation

Curated by ChEMBL


Assay Description
Tested for 50% inhibition of Angiotensin converting enzyme(ACE) obtained from rabbit lung (in vitro)


J Med Chem 37: 1823-32 (1994)


Article DOI: 10.1021/jm00038a011
BindingDB Entry DOI: 10.7270/Q280537C
More data for this
Ligand-Target Pair
Xaa-Pro aminopeptidase 1


(Homo sapiens (Human))
BDBM50078398
PNG
(2-[(S)-2-((S)-1-Carbamoyl-ethylcarbamoyl)-pyrrolid...)
Show SMILES C[C@H](NC(=O)[C@@H]1CCCN1C(CCc1ccccc1)C(O)=O)C(N)=O
Show InChI InChI=1S/C18H25N3O4/c1-12(16(19)22)20-17(23)14-8-5-11-21(14)15(18(24)25)10-9-13-6-3-2-4-7-13/h2-4,6-7,12,14-15H,5,8-11H2,1H3,(H2,19,22)(H,20,23)(H,24,25)/t12-,14-,15?/m0/s1
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n/an/a 7.20E+5n/an/an/an/an/an/a



Pharmacia and Upjohn

Curated by ChEMBL


Assay Description
Inhibition against cytosolic Aminopeptidase P from human heart.


J Med Chem 42: 2394-402 (1999)


Article DOI: 10.1021/jm9805642
BindingDB Entry DOI: 10.7270/Q2N878ZS
More data for this
Ligand-Target Pair
Xaa-Pro aminopeptidase 1


(Homo sapiens (Human))
BDBM50078398
PNG
(2-[(S)-2-((S)-1-Carbamoyl-ethylcarbamoyl)-pyrrolid...)
Show SMILES C[C@H](NC(=O)[C@@H]1CCCN1C(CCc1ccccc1)C(O)=O)C(N)=O
Show InChI InChI=1S/C18H25N3O4/c1-12(16(19)22)20-17(23)14-8-5-11-21(14)15(18(24)25)10-9-13-6-3-2-4-7-13/h2-4,6-7,12,14-15H,5,8-11H2,1H3,(H2,19,22)(H,20,23)(H,24,25)/t12-,14-,15?/m0/s1
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n/an/a 5.70E+3n/an/an/an/an/an/a



Pharmacia and Upjohn

Curated by ChEMBL


Assay Description
Inhibition against Aminopeptidase P from human platelets.


J Med Chem 42: 2394-402 (1999)


Article DOI: 10.1021/jm9805642
BindingDB Entry DOI: 10.7270/Q2N878ZS
More data for this
Ligand-Target Pair
Xaa-Pro aminopeptidase 2


(Rattus norvegicus)
BDBM50078398
PNG
(2-[(S)-2-((S)-1-Carbamoyl-ethylcarbamoyl)-pyrrolid...)
Show SMILES C[C@H](NC(=O)[C@@H]1CCCN1C(CCc1ccccc1)C(O)=O)C(N)=O
Show InChI InChI=1S/C18H25N3O4/c1-12(16(19)22)20-17(23)14-8-5-11-21(14)15(18(24)25)10-9-13-6-3-2-4-7-13/h2-4,6-7,12,14-15H,5,8-11H2,1H3,(H2,19,22)(H,20,23)(H,24,25)/t12-,14-,15?/m0/s1
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n/an/a 3.80E+3n/an/an/an/an/an/a



Pharmacia and Upjohn

Curated by ChEMBL


Assay Description
Activity against membrane bound rat aminopeptidase P


J Med Chem 42: 2394-402 (1999)


Article DOI: 10.1021/jm9805642
BindingDB Entry DOI: 10.7270/Q2N878ZS
More data for this
Ligand-Target Pair
Membrane-bound aminopeptidase P (APP2)


(Homo sapiens (Human))
BDBM50078398
PNG
(2-[(S)-2-((S)-1-Carbamoyl-ethylcarbamoyl)-pyrrolid...)
Show SMILES C[C@H](NC(=O)[C@@H]1CCCN1C(CCc1ccccc1)C(O)=O)C(N)=O
Show InChI InChI=1S/C18H25N3O4/c1-12(16(19)22)20-17(23)14-8-5-11-21(14)15(18(24)25)10-9-13-6-3-2-4-7-13/h2-4,6-7,12,14-15H,5,8-11H2,1H3,(H2,19,22)(H,20,23)(H,24,25)/t12-,14-,15?/m0/s1
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n/an/a 8.40E+3n/an/an/an/an/an/a



Pharmacia and Upjohn

Curated by ChEMBL


Assay Description
Inhibition against membrane bound monkey aminopeptidase P


J Med Chem 42: 2394-402 (1999)


Article DOI: 10.1021/jm9805642
BindingDB Entry DOI: 10.7270/Q2N878ZS
More data for this
Ligand-Target Pair
Xaa-Pro dipeptidase


(Homo sapiens (Human))
BDBM50078398
PNG
(2-[(S)-2-((S)-1-Carbamoyl-ethylcarbamoyl)-pyrrolid...)
Show SMILES C[C@H](NC(=O)[C@@H]1CCCN1C(CCc1ccccc1)C(O)=O)C(N)=O
Show InChI InChI=1S/C18H25N3O4/c1-12(16(19)22)20-17(23)14-8-5-11-21(14)15(18(24)25)10-9-13-6-3-2-4-7-13/h2-4,6-7,12,14-15H,5,8-11H2,1H3,(H2,19,22)(H,20,23)(H,24,25)/t12-,14-,15?/m0/s1
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n/an/a>2.00E+6n/an/an/an/an/an/a



Pharmacia and Upjohn

Curated by ChEMBL


Assay Description
Inhibition against Prolidase from pig kidney.


J Med Chem 42: 2394-402 (1999)


Article DOI: 10.1021/jm9805642
BindingDB Entry DOI: 10.7270/Q2N878ZS
More data for this
Ligand-Target Pair
Membrane-bound aminopeptidase P (APP2)


(Homo sapiens (Human))
BDBM50078398
PNG
(2-[(S)-2-((S)-1-Carbamoyl-ethylcarbamoyl)-pyrrolid...)
Show SMILES C[C@H](NC(=O)[C@@H]1CCCN1C(CCc1ccccc1)C(O)=O)C(N)=O
Show InChI InChI=1S/C18H25N3O4/c1-12(16(19)22)20-17(23)14-8-5-11-21(14)15(18(24)25)10-9-13-6-3-2-4-7-13/h2-4,6-7,12,14-15H,5,8-11H2,1H3,(H2,19,22)(H,20,23)(H,24,25)/t12-,14-,15?/m0/s1
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n/an/a 2.60E+3n/an/an/an/an/an/a



Pharmacia and Upjohn

Curated by ChEMBL


Assay Description
Inhibition against membrane bound human aminopeptidase P


J Med Chem 42: 2394-402 (1999)


Article DOI: 10.1021/jm9805642
BindingDB Entry DOI: 10.7270/Q2N878ZS
More data for this
Ligand-Target Pair
Leucine aminopeptidase


(Homo sapiens (Human))
BDBM50078398
PNG
(2-[(S)-2-((S)-1-Carbamoyl-ethylcarbamoyl)-pyrrolid...)
Show SMILES C[C@H](NC(=O)[C@@H]1CCCN1C(CCc1ccccc1)C(O)=O)C(N)=O
Show InChI InChI=1S/C18H25N3O4/c1-12(16(19)22)20-17(23)14-8-5-11-21(14)15(18(24)25)10-9-13-6-3-2-4-7-13/h2-4,6-7,12,14-15H,5,8-11H2,1H3,(H2,19,22)(H,20,23)(H,24,25)/t12-,14-,15?/m0/s1
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n/an/a>1.00E+6n/an/an/an/an/an/a



Pharmacia and Upjohn

Curated by ChEMBL


Assay Description
Inhibition against Leucyl aminopeptidase from pig kidney.


J Med Chem 42: 2394-402 (1999)


Article DOI: 10.1021/jm9805642
BindingDB Entry DOI: 10.7270/Q2N878ZS
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Oryctolagus cuniculus)
BDBM50017129
PNG
((S)-1-((S)-2-((R)-1-ethoxy-1-oxo-4-phenylbutan-2-y...)
Show SMILES CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1
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n/an/a 123n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of rabbit lung ACE assessed as hippuryl-histidyl-leucine hydrolysis after 30 mins by colorimetric method


Bioorg Med Chem 23: 3526-33 (2015)


Article DOI: 10.1016/j.bmc.2015.04.024
BindingDB Entry DOI: 10.7270/Q2DB83M4
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Rattus norvegicus)
BDBM50011192
PNG
((R)-1-[(S)-2-((S)-1-Carboxy-3-phenyl-propylamino)-...)
Show SMILES CC(NC(CCc1ccccc1)C(O)=O)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C18H24N2O5/c1-12(16(21)20-11-5-8-15(20)18(24)25)19-14(17(22)23)10-9-13-6-3-2-4-7-13/h2-4,6-7,12,14-15,19H,5,8-11H2,1H3,(H,22,23)(H,24,25)/t12?,14?,15-/m0/s1
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n/an/a 0.950n/an/an/an/an/an/a



Research and Development Laboratories

Curated by ChEMBL


Assay Description
Compound was tested for inhibitory activity against angiotensin I converting enzyme


J Med Chem 34: 439-47 (1991)


Article DOI: 10.1021/jm00105a066
BindingDB Entry DOI: 10.7270/Q28P5ZGR
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Rattus norvegicus)
BDBM50017129
PNG
((S)-1-((S)-2-((R)-1-ethoxy-1-oxo-4-phenylbutan-2-y...)
Show SMILES CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1
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n/an/a 140n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of rat Angiotensin I converting enzyme (ACE), using Hip-Gly-Gly as synthetic substrate.


J Med Chem 30: 992-8 (1987)


Article DOI: 10.1021/jm00389a006
BindingDB Entry DOI: 10.7270/Q29C6Z02
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Homo sapiens (Human))
BDBM50017129
PNG
((S)-1-((S)-2-((R)-1-ethoxy-1-oxo-4-phenylbutan-2-y...)
Show SMILES CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1
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n/an/a 4.5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Angiotensin I converting enzyme


J Med Chem 28: 1603-6 (1985)


Article DOI: 10.1021/jm00149a010
BindingDB Entry DOI: 10.7270/Q2ZK5H7D
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Homo sapiens (Human))
BDBM50017129
PNG
((S)-1-((S)-2-((R)-1-ethoxy-1-oxo-4-phenylbutan-2-y...)
Show SMILES CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1
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n/an/a 140n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Angiotensin I converting enzyme from unpurified guinea pig serum


J Med Chem 28: 1291-5 (1985)


Article DOI: 10.1021/jm00147a030
BindingDB Entry DOI: 10.7270/Q2GF0V34
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Homo sapiens (Human))
BDBM50017129
PNG
((S)-1-((S)-2-((R)-1-ethoxy-1-oxo-4-phenylbutan-2-y...)
Show SMILES CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1
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n/an/a 140n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of guinea pig angiotensin I converting enzyme


J Med Chem 29: 1953-61 (1986)


Article DOI: 10.1021/jm00160a026
BindingDB Entry DOI: 10.7270/Q2PZ59DG
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Homo sapiens (Human))
BDBM50021268
PNG
(2-(1-Carboxymethyl-2-oxo-azonan-3-ylamino)-4-pheny...)
Show SMILES OC(=O)CN1CCCCCCC(NC(CCc2ccccc2)C(O)=O)C1=O
Show InChI InChI=1S/C20H28N2O5/c23-18(24)14-22-13-7-2-1-6-10-16(19(22)25)21-17(20(26)27)12-11-15-8-4-3-5-9-15/h3-5,8-9,16-17,21H,1-2,6-7,10-14H2,(H,23,24)(H,26,27)
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n/an/a 1.30E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration (isomer A) against Angiotensin I converting enzyme


J Med Chem 29: 251-60 (1986)


Article DOI: 10.1021/jm00152a014
BindingDB Entry DOI: 10.7270/Q2J67HH7
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Homo sapiens (Human))
BDBM50021267
PNG
(2-(1-Carboxymethyl-2-oxo-azocan-3-ylamino)-4-pheny...)
Show SMILES OC(=O)CN1CCCCCC(NC(CCc2ccccc2)C(O)=O)C1=O
Show InChI InChI=1S/C19H26N2O5/c22-17(23)13-21-12-6-2-5-9-15(18(21)24)20-16(19(25)26)11-10-14-7-3-1-4-8-14/h1,3-4,7-8,15-16,20H,2,5-6,9-13H2,(H,22,23)(H,25,26)
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n/an/a 1.70E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration (isomer A) against Angiotensin I converting enzyme


J Med Chem 29: 251-60 (1986)


Article DOI: 10.1021/jm00152a014
BindingDB Entry DOI: 10.7270/Q2J67HH7
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Homo sapiens (Human))
BDBM50021269
PNG
(2-(1-Carboxymethyl-2-oxo-azepan-3-ylamino)-4-pheny...)
Show SMILES OC(=O)CN1CCCCC(NC(CCc2ccccc2)C(O)=O)C1=O
Show InChI InChI=1S/C18H24N2O5/c21-16(22)12-20-11-5-4-8-14(17(20)23)19-15(18(24)25)10-9-13-6-2-1-3-7-13/h1-3,6-7,14-15,19H,4-5,8-12H2,(H,21,22)(H,24,25)
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n/an/a 700n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration (isomer A) against Angiotensin I converting enzyme


J Med Chem 29: 251-60 (1986)


Article DOI: 10.1021/jm00152a014
BindingDB Entry DOI: 10.7270/Q2J67HH7
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Homo sapiens (Human))
BDBM50017129
PNG
((S)-1-((S)-2-((R)-1-ethoxy-1-oxo-4-phenylbutan-2-y...)
Show SMILES CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1
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n/an/a 140n/an/an/an/an/an/a



University of Calgary

Curated by ChEMBL


Assay Description
Compound was tested for its inhibitory potency against Angiotensin I converting enzyme


J Med Chem 34: 511-7 (1991)


Article DOI: 10.1021/jm00106a005
BindingDB Entry DOI: 10.7270/Q2JS9R1G
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Homo sapiens (Human))
BDBM50017129
PNG
((S)-1-((S)-2-((R)-1-ethoxy-1-oxo-4-phenylbutan-2-y...)
Show SMILES CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1
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n/an/a 1.27E+3n/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Compound tested in vitro for inhibition of Angiotensin I converting enzyme


J Med Chem 32: 1600-6 (1989)


Article DOI: 10.1021/jm00127a033
BindingDB Entry DOI: 10.7270/Q2M61KVW
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Homo sapiens (Human))
BDBM50017129
PNG
((S)-1-((S)-2-((R)-1-ethoxy-1-oxo-4-phenylbutan-2-y...)
Show SMILES CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1
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n/an/a 4.5n/an/an/an/an/an/a



University of Queensland

Curated by ChEMBL


Assay Description
Inhibitory activity against angiotensin I converting enzyme (ACE)


J Med Chem 43: 305-41 (2000)

Checked by Author
Article DOI: 10.1021/jm990412m
BindingDB Entry DOI: 10.7270/Q2JD4XH4
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Homo sapiens (Human))
BDBM50017129
PNG
((S)-1-((S)-2-((R)-1-ethoxy-1-oxo-4-phenylbutan-2-y...)
Show SMILES CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1
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n/an/a 1.20E+3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of Angiotensin I converting enzyme (ACE) in Bothrops jararaca venom


J Med Chem 45: 5609-16 (2002)


Article DOI: 10.1021/jm020424z
BindingDB Entry DOI: 10.7270/Q270825W
More data for this
Ligand-Target Pair
Angiotensin-Converting Enzyme 2


(Homo sapiens (Human))
BDBM50017129
PNG
((S)-1-((S)-2-((R)-1-ethoxy-1-oxo-4-phenylbutan-2-y...)
Show SMILES CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1
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n/an/a 1.20n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition against angiotensin converting enzyme (ACE)


Bioorg Med Chem Lett 4: 2673-2676 (1994)


Article DOI: 10.1016/S0960-894X(01)80694-6
BindingDB Entry DOI: 10.7270/Q2X34XXT
More data for this
Ligand-Target Pair
Multidrug and toxin extrusion protein 1


(Homo sapiens (Human))
BDBM50017129
PNG
((S)-1-((S)-2-((R)-1-ethoxy-1-oxo-4-phenylbutan-2-y...)
Show SMILES CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1
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n/an/a>5.00E+5n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay


J Med Chem 56: 781-95 (2013)


Article DOI: 10.1021/jm301302s
BindingDB Entry DOI: 10.7270/Q2F76DWZ
More data for this
Ligand-Target Pair
Succinyl-diaminopimelate desuccinylase


(Haemophilus influenzae)
BDBM50017129
PNG
((S)-1-((S)-2-((R)-1-ethoxy-1-oxo-4-phenylbutan-2-y...)
Show SMILES CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1
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n/an/a>1.00E+6n/an/an/an/an/an/a



Loyola University

Curated by ChEMBL


Assay Description
Inhibition of Haemophilus influenzae recombinant DapE


Bioorg Med Chem Lett 19: 6350-2 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.077
BindingDB Entry DOI: 10.7270/Q2833T06
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Homo sapiens (Human))
BDBM50021129
PNG
(1-[2-(1-Carboxy-3-phenyl-propylamino)-propionyl]-p...)
Show SMILES C[C@H](NC(CCc1ccccc1)C(O)=O)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C18H24N2O5/c1-12(16(21)20-11-5-8-15(20)18(24)25)19-14(17(22)23)10-9-13-6-3-2-4-7-13/h2-4,6-7,12,14-15,19H,5,8-11H2,1H3,(H,22,23)(H,24,25)/t12-,14?,15-/m0/s1
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n/an/a 1.20n/an/an/an/an/an/a



Washington University

Curated by ChEMBL


Assay Description
Inhibitory activity against angiotensin converting enzyme (ACE)


J Med Chem 36: 2390-403 (1993)


Article DOI: 10.1021/jm00068a017
BindingDB Entry DOI: 10.7270/Q2Z320V9
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Homo sapiens (Human))
BDBM50405267
PNG
(CHEMBL2370859)
Show SMILES C[C@H](NC(=O)CCc1ccccc1)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C17H22N2O4/c1-12(16(21)19-11-5-8-14(19)17(22)23)18-15(20)10-9-13-6-3-2-4-7-13/h2-4,6-7,12,14H,5,8-11H2,1H3,(H,18,20)(H,22,23)/t12-,14-/m0/s1
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n/an/a 3.30E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Angiotensin I converting enzyme


J Med Chem 28: 434-42 (1985)


Article DOI: 10.1021/jm00382a008
BindingDB Entry DOI: 10.7270/Q2RV0PVJ
More data for this
Ligand-Target Pair
Angiotensin-Converting Enzyme 2


(Homo sapiens (Human))
BDBM50017129
PNG
((S)-1-((S)-2-((R)-1-ethoxy-1-oxo-4-phenylbutan-2-y...)
Show SMILES CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1
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n/an/a 1.20E+3n/an/an/an/an/an/a



Rorer Central Research

Curated by ChEMBL


Assay Description
In vitro inhibition of Angiotensin I converting enzyme in Hog plasma


J Med Chem 33: 1606-15 (1990)


Article DOI: 10.1021/jm00168a013
BindingDB Entry DOI: 10.7270/Q2CF9QPK
More data for this
Ligand-Target Pair
Oligopeptide transporter small intestine isoform


(Homo sapiens (Human))
BDBM50017129
PNG
((S)-1-((S)-2-((R)-1-ethoxy-1-oxo-4-phenylbutan-2-y...)
Show SMILES CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1
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n/an/a 1.50E+7n/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of Gly-Sar uptake (Gly-Sar: 20 uM) in PEPT1-expressing CHO cells


Pharm Res 15: 1154-9 (1998)


Article DOI: 10.1023/a:1011919319810
BindingDB Entry DOI: 10.7270/Q2BC40M3
More data for this
Ligand-Target Pair
Oligopeptide transporter small intestine isoform


(Homo sapiens (Human))
BDBM50017129
PNG
((S)-1-((S)-2-((R)-1-ethoxy-1-oxo-4-phenylbutan-2-y...)
Show SMILES CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1
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n/an/a 4.50E+6n/an/an/an/an/an/a



The University of Michigan

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of Gly-Sar uptake (Gly-Sar: 20 uM) in PEPT1-expressing CHO cells


J Pharm Sci 88: 347-50 (1999)


Article DOI: 10.1021/js980132e
BindingDB Entry DOI: 10.7270/Q22V2H6H
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Homo sapiens (Human))
BDBM50021269
PNG
(2-(1-Carboxymethyl-2-oxo-azepan-3-ylamino)-4-pheny...)
Show SMILES OC(=O)CN1CCCCC(NC(CCc2ccccc2)C(O)=O)C1=O
Show InChI InChI=1S/C18H24N2O5/c21-16(22)12-20-11-5-4-8-14(17(20)23)19-15(18(24)25)10-9-13-6-2-1-3-7-13/h1-3,6-7,14-15,19H,4-5,8-12H2,(H,21,22)(H,24,25)
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n/an/a 19n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration (isomer B) against Angiotensin I converting enzyme


J Med Chem 29: 251-60 (1986)


Article DOI: 10.1021/jm00152a014
BindingDB Entry DOI: 10.7270/Q2J67HH7
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Homo sapiens (Human))
BDBM50021266
PNG
(2-(1-Carboxymethyl-2-oxo-piperidin-3-ylamino)-4-ph...)
Show SMILES OC(=O)CN1CCCC(NC(CCc2ccccc2)C(O)=O)C1=O
Show InChI InChI=1S/C17H22N2O5/c20-15(21)11-19-10-4-7-13(16(19)22)18-14(17(23)24)9-8-12-5-2-1-3-6-12/h1-3,5-6,13-14,18H,4,7-11H2,(H,20,21)(H,23,24)
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n/an/a 1.70E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration (isomer B) against Angiotensin I converting enzyme


J Med Chem 29: 251-60 (1986)


Article DOI: 10.1021/jm00152a014
BindingDB Entry DOI: 10.7270/Q2J67HH7
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Homo sapiens (Human))
BDBM50021268
PNG
(2-(1-Carboxymethyl-2-oxo-azonan-3-ylamino)-4-pheny...)
Show SMILES OC(=O)CN1CCCCCCC(NC(CCc2ccccc2)C(O)=O)C1=O
Show InChI InChI=1S/C20H28N2O5/c23-18(24)14-22-13-7-2-1-6-10-16(19(22)25)21-17(20(26)27)12-11-15-8-4-3-5-9-15/h3-5,8-9,16-17,21H,1-2,6-7,10-14H2,(H,23,24)(H,26,27)
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n/an/a 8.10n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration (isomer B) against Angiotensin I converting enzyme


J Med Chem 29: 251-60 (1986)


Article DOI: 10.1021/jm00152a014
BindingDB Entry DOI: 10.7270/Q2J67HH7
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Homo sapiens (Human))
BDBM50021270
PNG
(2-(1-Carboxymethyl-2-oxo-pyrrolidin-3-ylamino)-4-p...)
Show SMILES OC(=O)CN1CCC(NC(CCc2ccccc2)C(O)=O)C1=O
Show InChI InChI=1S/C16H20N2O5/c19-14(20)10-18-9-8-12(15(18)21)17-13(16(22)23)7-6-11-4-2-1-3-5-11/h1-5,12-13,17H,6-10H2,(H,19,20)(H,22,23)
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n/an/a 1.90E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration (isomer B) against Angiotensin I converting enzyme


J Med Chem 29: 251-60 (1986)


Article DOI: 10.1021/jm00152a014
BindingDB Entry DOI: 10.7270/Q2J67HH7
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Oryctolagus cuniculus)
BDBM50011192
PNG
((R)-1-[(S)-2-((S)-1-Carboxy-3-phenyl-propylamino)-...)
Show SMILES CC(NC(CCc1ccccc1)C(O)=O)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C18H24N2O5/c1-12(16(21)20-11-5-8-15(20)18(24)25)19-14(17(22)23)10-9-13-6-3-2-4-7-13/h2-4,6-7,12,14-15,19H,5,8-11H2,1H3,(H,22,23)(H,24,25)/t12?,14?,15-/m0/s1
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n/an/a 5.70n/an/an/an/an/an/a



Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against rabbit lung Angiotensin I converting enzyme with 5 mM hippurylhistidylleucine as substrate


J Med Chem 30: 1984-91 (1987)


Article DOI: 10.1021/jm00394a009
BindingDB Entry DOI: 10.7270/Q2Q52NMJ
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Homo sapiens (Human))
BDBM50021267
PNG
(2-(1-Carboxymethyl-2-oxo-azocan-3-ylamino)-4-pheny...)
Show SMILES OC(=O)CN1CCCCCC(NC(CCc2ccccc2)C(O)=O)C1=O
Show InChI InChI=1S/C19H26N2O5/c22-17(23)13-21-12-6-2-5-9-15(18(21)24)20-16(19(25)26)11-10-14-7-3-1-4-8-14/h1,3-4,7-8,15-16,20H,2,5-6,9-13H2,(H,22,23)(H,25,26)
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n/an/a 4.80n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration (isomer B) against Angiotensin I converting enzyme


J Med Chem 29: 251-60 (1986)


Article DOI: 10.1021/jm00152a014
BindingDB Entry DOI: 10.7270/Q2J67HH7
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens (Human))
BDBM66979
PNG
((2S)-1-[(2S)-6-amino-2-[[(1S)-1-carboxy-3-phenyl-p...)
Show SMILES NCCCC[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C21H31N3O5/c22-13-5-4-9-16(19(25)24-14-6-10-18(24)21(28)29)23-17(20(26)27)12-11-15-7-2-1-3-8-15/h1-3,7-8,16-18,23H,4-6,9-14,22H2,(H,26,27)(H,28,29)/t16-,17-,18-/m0/s1
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n/an/an/an/a>3.50E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50125258
PNG
((S)-1-[(S)-6-Amino-2-((S)-2-{[(S)-1-((S)-2-amino-3...)
Show SMILES NCCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccccc1)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C28H42N6O7/c29-13-5-4-10-20(27(39)34-15-7-12-23(34)28(40)41)31-24(36)21(17-35)32-25(37)22-11-6-14-33(22)26(38)19(30)16-18-8-2-1-3-9-18/h1-3,8-9,19-23,35H,4-7,10-17,29-30H2,(H,31,36)(H,32,37)(H,40,41)/t19-,20-,21-,22-,23-/m0/s1
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n/an/a 1.50E+4n/an/an/an/an/an/a



University of North Carolina at Wilmington

Curated by ChEMBL


Assay Description
Inhibitory activity against non-selective opiate receptor


Bioorg Med Chem Lett 13: 1029-31 (2003)


Article DOI: 10.1016/s0960-894x(03)00082-9
BindingDB Entry DOI: 10.7270/Q2FB53GH
More data for this
Ligand-Target Pair