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69 similar compounds to monomer 50007102

Compile data set for download or QSAR
Wt: 371.9
BDBM50455603
Wt: 371.9
BDBM50001052
Wt: 287.4
BDBM50001045
Wt: 231.3
BDBM50001041
Wt: 363.5
BDBM50001050
Wt: 349.5
BDBM50001046
Wt: 287.4
BDBM50001027
Wt: 231.3
BDBM50001038
Wt: 363.5
BDBM50001032
Wt: 349.5
BDBM50001042
Wt: 402.3
BDBM83453
Wt: 301.4
BDBM81932
Wt: 301.4
BDBM81933
Wt: 321.4
BDBM50001043
Wt: 321.4
BDBM50001019
Displayed 1 to 15 (of 69 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 26 hits for monomerid = 50455603,50001052,50001045,50001041,50001050,50001046,50001027,50001038,50001032,50001042,83453,81932,81933,50001043,50001019   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50001019
PNG
(6,11-Dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,...)
Show SMILES C[C@H]1[C@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2CCc1ccccc1
Show InChI InChI=1S/C22H27NO/c1-16-21-14-18-8-9-19(24)15-20(18)22(16,2)11-13-23(21)12-10-17-6-4-3-5-7-17/h3-9,15-16,21,24H,10-14H2,1-2H3/t16-,21+,22-/m0/s1
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0.200n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.


J Med Chem 35: 2812-8 (1992)


Article DOI: 10.1021/jm00093a014
BindingDB Entry DOI: 10.7270/Q29W0G3H
More data for this
Ligand-Target Pair
Sigma-1 receptor


(Cavia porcellus (Guinea pig))
BDBM50001019
PNG
(6,11-Dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,...)
Show SMILES C[C@H]1[C@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2CCc1ccccc1
Show InChI InChI=1S/C22H27NO/c1-16-21-14-18-8-9-19(24)15-20(18)22(16,2)11-13-23(21)12-10-17-6-4-3-5-7-17/h3-9,15-16,21,24H,10-14H2,1-2H3/t16-,21+,22-/m0/s1
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0.200n/an/an/an/an/an/an/an/a



University of Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocin from sigma1 receptor in guinea pig brain P2 membranes after 120 mins


Eur J Med Chem 125: 603-610 (2017)


Article DOI: 10.1016/j.ejmech.2016.09.077
More data for this
Ligand-Target Pair
Sigma-1 receptor


(Cavia porcellus (Guinea pig))
BDBM50001043
PNG
(6,11-Dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,...)
Show SMILES C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCc1ccccc1
Show InChI InChI=1S/C22H27NO/c1-16-21-14-18-8-9-19(24)15-20(18)22(16,2)11-13-23(21)12-10-17-6-4-3-5-7-17/h3-9,15-16,21,24H,10-14H2,1-2H3/t16-,21+,22-/m1/s1
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3.80n/an/an/an/an/an/an/an/a



University of Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-PTZ from sigma1 receptor in guinea pig brain membranes after 150 mins in presence of 1 mM DPH by liquid scintillation counting m...


Eur J Med Chem 125: 603-610 (2017)


Article DOI: 10.1016/j.ejmech.2016.09.077
More data for this
Ligand-Target Pair
Sigma-1 receptor


(Cavia porcellus (Guinea pig))
BDBM50001043
PNG
(6,11-Dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,...)
Show SMILES C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCc1ccccc1
Show InChI InChI=1S/C22H27NO/c1-16-21-14-18-8-9-19(24)15-20(18)22(16,2)11-13-23(21)12-10-17-6-4-3-5-7-17/h3-9,15-16,21,24H,10-14H2,1-2H3/t16-,21+,22-/m1/s1
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3.90n/an/an/an/an/an/an/an/a



University of Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-PTZ from sigma1 receptor in guinea pig brain membranes after 150 mins by liquid scintillation counting method


Eur J Med Chem 125: 603-610 (2017)


Article DOI: 10.1016/j.ejmech.2016.09.077
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50001043
PNG
(6,11-Dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,...)
Show SMILES C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCc1ccccc1
Show InChI InChI=1S/C22H27NO/c1-16-21-14-18-8-9-19(24)15-20(18)22(16,2)11-13-23(21)12-10-17-6-4-3-5-7-17/h3-9,15-16,21,24H,10-14H2,1-2H3/t16-,21+,22-/m1/s1
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3.90n/an/an/an/an/an/an/an/a



University of Catania

Curated by ChEMBL


Assay Description
Displacement of [3H] DAMGO from mu opioid receptor in Sprague-Dawley rat whole brain membranes after 2.5 hrs by liquid scintillation method


Eur J Med Chem 125: 603-610 (2017)


Article DOI: 10.1016/j.ejmech.2016.09.077
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50001046
PNG
(6,11-Dimethyl-3-(4-phenyl-butyl)-1,2,3,4,5,6-hexah...)
Show SMILES C[C@H]1[C@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2CCCCc1ccccc1
Show InChI InChI=1S/C24H31NO/c1-18-23-16-20-11-12-21(26)17-22(20)24(18,2)13-15-25(23)14-7-6-10-19-8-4-3-5-9-19/h3-5,8-9,11-12,17-18,23,26H,6-7,10,13-16H2,1-2H3/t18-,23+,24-/m0/s1
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4n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.


J Med Chem 35: 2812-8 (1992)


Article DOI: 10.1021/jm00093a014
BindingDB Entry DOI: 10.7270/Q29W0G3H
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50001043
PNG
(6,11-Dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,...)
Show SMILES C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCc1ccccc1
Show InChI InChI=1S/C22H27NO/c1-16-21-14-18-8-9-19(24)15-20(18)22(16,2)11-13-23(21)12-10-17-6-4-3-5-7-17/h3-9,15-16,21,24H,10-14H2,1-2H3/t16-,21+,22-/m1/s1
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4.30n/an/an/an/an/an/an/an/a



University of Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-PTZ from sigma1 receptor in guinea pig brain membranes after 150 mins in presence of 1 mM DPH by liquid scintillation counting m...


Eur J Med Chem 125: 603-610 (2017)


Article DOI: 10.1016/j.ejmech.2016.09.077
More data for this
Ligand-Target Pair
OPRK1


(Frog)
BDBM81932
PNG
((-)-alpha-(1R,5R,9R)-5,9-Dimethyl-2-L-tetrahydrofu...)
Show SMILES CC1[C@H]2Cc3ccc(O)cc3[C@]1(C)CCN2C[C@H]1CCCO1
Show InChI InChI=1S/C19H27NO2/c1-13-18-10-14-5-6-15(21)11-17(14)19(13,2)7-8-20(18)12-16-4-3-9-22-16/h5-6,11,13,16,18,21H,3-4,7-10,12H2,1-2H3/t13?,16-,18-,19-/m1/s1
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4.80n/an/an/an/an/an/an/an/a



Biological Research Center of Hungarian Academy of Sciences

Curated by PDSP Ki Database




Neurochem Res 15: 899-904 (1990)


BindingDB Entry DOI: 10.7270/Q25M6460
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50001027
PNG
(3,6,11-Trimethyl-1,2,3,4,5,6-hexahydro-2,6-methano...)
Show SMILES CC(C)CCN1CC[C@@]2(C)[C@@H](C)[C@H]1Cc1ccc(O)cc21
Show InChI InChI=1S/C19H29NO/c1-13(2)7-9-20-10-8-19(4)14(3)18(20)11-15-5-6-16(21)12-17(15)19/h5-6,12-14,18,21H,7-11H2,1-4H3/t14-,18+,19-/m0/s1
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4.90n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.


J Med Chem 35: 2812-8 (1992)


Article DOI: 10.1021/jm00093a014
BindingDB Entry DOI: 10.7270/Q29W0G3H
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50001038
PNG
(6,11-Dimethyl-3-(3-methyl-butyl)-1,2,3,4,5,6-hexah...)
Show SMILES C[C@H]1[C@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2C
Show InChI InChI=1S/C15H21NO/c1-10-14-8-11-4-5-12(17)9-13(11)15(10,2)6-7-16(14)3/h4-5,9-10,14,17H,6-8H2,1-3H3/t10-,14+,15-/m0/s1
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11n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.


J Med Chem 35: 2812-8 (1992)


Article DOI: 10.1021/jm00093a014
BindingDB Entry DOI: 10.7270/Q29W0G3H
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50001052
PNG
(6,11-Dimethyl-3-(3-phenyl-propyl)-1,2,3,4,5,6-hexa...)
Show SMILES C[C@H]1[C@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2CCCc1ccccc1
Show InChI InChI=1S/C23H29NO.ClH/c1-17-22-15-19-10-11-20(25)16-21(19)23(17,2)12-14-24(22)13-6-9-18-7-4-3-5-8-18;/h3-5,7-8,10-11,16-17,22,25H,6,9,12-15H2,1-2H3;1H/t17-,22+,23-;/m0./s1
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20n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.


J Med Chem 35: 2812-8 (1992)


Article DOI: 10.1021/jm00093a014
BindingDB Entry DOI: 10.7270/Q29W0G3H
More data for this
Ligand-Target Pair
Sigma-1 receptor


(Cavia porcellus (Guinea pig))
BDBM50001043
PNG
(6,11-Dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,...)
Show SMILES C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCc1ccccc1
Show InChI InChI=1S/C22H27NO/c1-16-21-14-18-8-9-19(24)15-20(18)22(16,2)11-13-23(21)12-10-17-6-4-3-5-7-17/h3-9,15-16,21,24H,10-14H2,1-2H3/t16-,21+,22-/m1/s1
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55n/an/an/an/an/an/an/an/a



University of Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocin from sigma1 receptor in guinea pig brain P2 membranes after 120 mins


Eur J Med Chem 125: 603-610 (2017)


Article DOI: 10.1016/j.ejmech.2016.09.077
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50001043
PNG
(6,11-Dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,...)
Show SMILES C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCc1ccccc1
Show InChI InChI=1S/C22H27NO/c1-16-21-14-18-8-9-19(24)15-20(18)22(16,2)11-13-23(21)12-10-17-6-4-3-5-7-17/h3-9,15-16,21,24H,10-14H2,1-2H3/t16-,21+,22-/m1/s1
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55n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.


J Med Chem 35: 2812-8 (1992)


Article DOI: 10.1021/jm00093a014
BindingDB Entry DOI: 10.7270/Q29W0G3H
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50001019
PNG
(6,11-Dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,...)
Show SMILES C[C@H]1[C@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2CCc1ccccc1
Show InChI InChI=1S/C22H27NO/c1-16-21-14-18-8-9-19(24)15-20(18)22(16,2)11-13-23(21)12-10-17-6-4-3-5-7-17/h3-9,15-16,21,24H,10-14H2,1-2H3/t16-,21+,22-/m0/s1
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62n/an/an/an/an/an/an/an/a



University of Catania

Curated by ChEMBL


Assay Description
Displacement of [3H] DAMGO from mu opioid receptor in Sprague-Dawley rat whole brain membranes after 2.5 hrs by liquid scintillation method


Eur J Med Chem 125: 603-610 (2017)


Article DOI: 10.1016/j.ejmech.2016.09.077
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50001050
PNG
(6,11-Dimethyl-3-(5-phenyl-pentyl)-1,2,3,4,5,6-hexa...)
Show SMILES C[C@H]1[C@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2CCCCCc1ccccc1
Show InChI InChI=1S/C25H33NO/c1-19-24-17-21-12-13-22(27)18-23(21)25(19,2)14-16-26(24)15-8-4-7-11-20-9-5-3-6-10-20/h3,5-6,9-10,12-13,18-19,24,27H,4,7-8,11,14-17H2,1-2H3/t19-,24+,25-/m0/s1
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68n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.


J Med Chem 35: 2812-8 (1992)


Article DOI: 10.1021/jm00093a014
BindingDB Entry DOI: 10.7270/Q29W0G3H
More data for this
Ligand-Target Pair
Sigma-1 receptor


(Cavia porcellus (Guinea pig))
BDBM50001019
PNG
(6,11-Dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,...)
Show SMILES C[C@H]1[C@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2CCc1ccccc1
Show InChI InChI=1S/C22H27NO/c1-16-21-14-18-8-9-19(24)15-20(18)22(16,2)11-13-23(21)12-10-17-6-4-3-5-7-17/h3-9,15-16,21,24H,10-14H2,1-2H3/t16-,21+,22-/m0/s1
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80n/an/an/an/an/an/an/an/a



University of Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-PTZ from sigma1 receptor in guinea pig brain membranes after 150 mins in presence of DPH solvent by liquid scintillation countin...


Eur J Med Chem 125: 603-610 (2017)


Article DOI: 10.1016/j.ejmech.2016.09.077
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50001019
PNG
(6,11-Dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,...)
Show SMILES C[C@H]1[C@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2CCc1ccccc1
Show InChI InChI=1S/C22H27NO/c1-16-21-14-18-8-9-19(24)15-20(18)22(16,2)11-13-23(21)12-10-17-6-4-3-5-7-17/h3-9,15-16,21,24H,10-14H2,1-2H3/t16-,21+,22-/m0/s1
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85n/an/an/an/an/an/an/an/a



University of Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]-PTZ from sigma1 receptor in guinea pig brain membranes after 150 mins in presence of 1 mM DPH by liquid scintillation counting m...


Eur J Med Chem 125: 603-610 (2017)


Article DOI: 10.1016/j.ejmech.2016.09.077
More data for this
Ligand-Target Pair
Opioid receptors; mu & delta


(Rattus norvegicus (rat))
BDBM50001043
PNG
(6,11-Dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,...)
Show SMILES C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCc1ccccc1
Show InChI InChI=1S/C22H27NO/c1-16-21-14-18-8-9-19(24)15-20(18)22(16,2)11-13-23(21)12-10-17-6-4-3-5-7-17/h3-9,15-16,21,24H,10-14H2,1-2H3/t16-,21+,22-/m1/s1
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123n/an/an/an/an/an/an/an/a



University of Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in Sprague-Dawley rat brain membranes by liquid scintillation counter method


Eur J Med Chem 125: 603-610 (2017)


Article DOI: 10.1016/j.ejmech.2016.09.077
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50001043
PNG
(6,11-Dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,...)
Show SMILES C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCc1ccccc1
Show InChI InChI=1S/C22H27NO/c1-16-21-14-18-8-9-19(24)15-20(18)22(16,2)11-13-23(21)12-10-17-6-4-3-5-7-17/h3-9,15-16,21,24H,10-14H2,1-2H3/t16-,21+,22-/m1/s1
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175n/an/an/an/an/an/an/an/a



University of Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]U69,593 from kappa opioid receptor in guinea pig brain membranes by liquid scintillation counter method


Eur J Med Chem 125: 603-610 (2017)


Article DOI: 10.1016/j.ejmech.2016.09.077
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50001032
PNG
(6,11-Dimethyl-3-(5-phenyl-pentyl)-1,2,3,4,5,6-hexa...)
Show SMILES C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCCCCc1ccccc1
Show InChI InChI=1S/C25H33NO/c1-19-24-17-21-12-13-22(27)18-23(21)25(19,2)14-16-26(24)15-8-4-7-11-20-9-5-3-6-10-20/h3,5-6,9-10,12-13,18-19,24,27H,4,7-8,11,14-17H2,1-2H3/t19-,24+,25-/m1/s1
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260n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.


J Med Chem 35: 2812-8 (1992)


Article DOI: 10.1021/jm00093a014
BindingDB Entry DOI: 10.7270/Q29W0G3H
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50001042
PNG
(6,11-Dimethyl-3-(4-phenyl-butyl)-1,2,3,4,5,6-hexah...)
Show SMILES C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCCCc1ccccc1
Show InChI InChI=1S/C24H31NO/c1-18-23-16-20-11-12-21(26)17-22(20)24(18,2)13-15-25(23)14-7-6-10-19-8-4-3-5-9-19/h3-5,8-9,11-12,17-18,23,26H,6-7,10,13-16H2,1-2H3/t18-,23+,24-/m1/s1
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270n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.


J Med Chem 35: 2812-8 (1992)


Article DOI: 10.1021/jm00093a014
BindingDB Entry DOI: 10.7270/Q29W0G3H
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50455603
PNG
(CHEMBL2368631)
Show SMILES C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCCc1ccccc1
Show InChI InChI=1S/C23H29NO.ClH/c1-17-22-15-19-10-11-20(25)16-21(19)23(17,2)12-14-24(22)13-6-9-18-7-4-3-5-8-18;/h3-5,7-8,10-11,16-17,22,25H,6,9,12-15H2,1-2H3;1H/t17-,22+,23-;/m1./s1
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343n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.


J Med Chem 35: 2812-8 (1992)


Article DOI: 10.1021/jm00093a014
BindingDB Entry DOI: 10.7270/Q29W0G3H
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50001045
PNG
(6,11-Dimethyl-3-(3-phenyl-propyl)-1,2,3,4,5,6-hexa...)
Show SMILES CC(C)CCN1CC[C@]2(C)[C@H](C)[C@@H]1Cc1ccc(O)cc21
Show InChI InChI=1S/C19H29NO/c1-13(2)7-9-20-10-8-19(4)14(3)18(20)11-15-5-6-16(21)12-17(15)19/h5-6,12-14,18,21H,7-11H2,1-4H3/t14-,18+,19-/m1/s1
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3.50E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.


J Med Chem 35: 2812-8 (1992)


Article DOI: 10.1021/jm00093a014
BindingDB Entry DOI: 10.7270/Q29W0G3H
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50001041
PNG
(3,6,11-Trimethyl-1,2,3,4,5,6-hexahydro-2,6-methano...)
Show SMILES C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@]1(C)CCN2C
Show InChI InChI=1S/C15H21NO/c1-10-14-8-11-4-5-12(17)9-13(11)15(10,2)6-7-16(14)3/h4-5,9-10,14,17H,6-8H2,1-3H3/t10-,14+,15-/m1/s1
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4.97E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.


J Med Chem 35: 2812-8 (1992)


Article DOI: 10.1021/jm00093a014
BindingDB Entry DOI: 10.7270/Q29W0G3H
More data for this
Ligand-Target Pair
OPRK1


(Frog)
BDBM81933
PNG
((+)-alpha-(1R,5R,9R)-5,9-Dimethyl-2-L-tetrahydrofu...)
Show SMILES CC1[C@H]2Cc3ccc(O)cc3[C@]1(C)CCN2C[C@@H]1CCCO1
Show InChI InChI=1S/C19H27NO2/c1-13-18-10-14-5-6-15(21)11-17(14)19(13,2)7-8-20(18)12-16-4-3-9-22-16/h5-6,11,13,16,18,21H,3-4,7-10,12H2,1-2H3/t13?,16-,18+,19+/m0/s1
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5.40E+3n/an/an/an/an/an/an/an/a



Biological Research Center of Hungarian Academy of Sciences

Curated by PDSP Ki Database




Neurochem Res 15: 899-904 (1990)


BindingDB Entry DOI: 10.7270/Q25M6460
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM83453
PNG
((-)-Phenazocine hydrobromide | MLS002320754 | SMR0...)
Show SMILES Br.CC1[C@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCc1ccccc1
Show InChI InChI=1S/C22H27NO.BrH/c1-16-21-14-18-8-9-19(24)15-20(18)22(16,2)11-13-23(21)12-10-17-6-4-3-5-7-17;/h3-9,15-16,21,24H,10-14H2,1-2H3;1H/t16?,21-,22-;/m1./s1
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n/an/an/an/a 551n/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q22V2DN3
More data for this
Ligand-Target Pair