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Found 49 Enz. Inhib. hit(s) with Target = 'Arylamine N-acetyltransferase 1'
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50014986(CHEMBL3262086)
Affinity DataIC50:  120nMAssay Description:Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50275074((Z)-5-(3',5'-Diiodo-4'-hydroxybenzylidene)-2-thiox...)
Affinity DataIC50:  138nMAssay Description:Inhibition of NAT1 in human ZR75 cell lysate assessed as acetylation of aryl amine using PABA as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50275074((Z)-5-(3',5'-Diiodo-4'-hydroxybenzylidene)-2-thiox...)
Affinity DataIC50:  330nMAssay Description:Inhibition of human recombinant NAT1 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50014944(CHEMBL3262085)
Affinity DataIC50:  540nMAssay Description:Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50274853((Z)-5-(3'-Hydroxybenzylidene)-2-thioxothiazolidin-...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human recombinant NAT1 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50014914(CHEMBL3262049)
Affinity DataIC50:  900nMAssay Description:Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50368688(CHEMBL2047717)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Homo sapiens (human) arylamine N-acetyltransferase 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50092273((Z)-5-(2'-Hydroxybenzylidene)-2-thioxothiazolidin-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human recombinant NAT1 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50274890((Z)-3-Amino-5-(4'-hydroxy-3',5-diiodobenzylidene)-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human recombinant NAT1 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50014912(CHEMBL1568345)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50014924(CHEMBL3262055)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50014943(CHEMBL3262084)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50014922(CHEMBL3262053)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50274887((Z)-5-(3',4'-Dichlorobenzylidene)-2-thioxothiazoli...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of human recombinant NAT1 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50240730((Z)-5-(4'-Hydroxy-3',5'-diiodobenzylidene)thiazoli...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of human recombinant NAT1 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50274886((Z)-5-(2'-Methylbenzylidene)-2-thioxothiazolidin-4...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of human recombinant NAT1 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50014913(CHEMBL3262048)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50014942(CHEMBL3262082)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50181730((Z)-5-(4'-Chlorobenzylidene)-2-thioxothiazolidin-4...)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of human recombinant NAT1 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50014987(CHEMBL3262087)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50014938(CHEMBL3262077)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50274889((Z)-5-(4'-Hydroxy-3',5'-diiodobenzylidene)-3-methy...)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of human recombinant NAT1 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50014925(CHEMBL3262056)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50274888((Z)-5-(4'-Biphenylmethylene)-2-thioxothiazolidin-4...)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of human recombinant NAT1 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50014928(CHEMBL3262059)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50014930(CHEMBL3262061)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50014932(CHEMBL3262073)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50014931(CHEMBL3262062)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50014929(CHEMBL3262060)
Affinity DataIC50:  1.03E+4nMAssay Description:Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50014923(CHEMBL3262054)
Affinity DataIC50:  1.21E+4nMAssay Description:Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50014927(CHEMBL3262058)
Affinity DataIC50:  1.21E+4nMAssay Description:Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50241154((Z)-5-(4'-Fluorobenzylidene)-2-thioxothiazolidin-4...)
Affinity DataIC50:  1.29E+4nMAssay Description:Inhibition of human recombinant NAT1 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50092271((Z)-5-Benzylidene-2-thioxothiazolidin-4-one | (Z)-...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human recombinant NAT1 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50014926(CHEMBL3262057)
Affinity DataIC50:  1.45E+4nMAssay Description:Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50247599((Z)-5-(4'-Hydroxybenzylidene)-2-thioxothiazolidin-...)
Affinity DataIC50:  1.69E+4nMAssay Description:Inhibition of human recombinant NAT1 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50274855((Z)-5-(3'-Methylbenzylidene)-2-thioxothiazolidin-4...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human recombinant NAT1 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50274854((Z)-5-(2'-Methoxybenzylidene)-2-thioxothiazolidin-...)
Affinity DataIC50:  1.76E+4nMAssay Description:Inhibition of human recombinant NAT1 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50014933(CHEMBL3262074)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50014937(CHEMBL3262076)
Affinity DataIC50:  1.93E+4nMAssay Description:Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50014934(CHEMBL3262075)
Affinity DataIC50:  2.21E+4nMAssay Description:Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50014916(CHEMBL3262050)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50014920(CHEMBL3262051)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50014921(CHEMBL3262052)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50241156((Z)-5-(4'-Methylbenzylidene)-2-thioxothiazolidin-4...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant NAT1 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50241489((Z)-5-(3'-Methoxybenzylidene)-2-thioxothiazolidin-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant NAT1 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50014941(CHEMBL3262081)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50014940(CHEMBL3262080)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50014939(CHEMBL3262078)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human NAT1 assessed as rate of free thiol coenzyme A production using arylamine and AcCoA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylamine N-acetyltransferase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50241157((Z)-5-(4'-Methoxybenzylidene)-2-thioxothiazolidin-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant NAT1 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed