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Found 82 Enz. Inhib. hit(s) with Target = 'Cysteine proteinase falcipain 2a'
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50578419(CHEMBL4857262)
Affinity DataKi:  2.49E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum falcipain-2 expressed in Escherichia coli M15 assessed as reduction in free AMC release using Z-FR-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50578421(CHEMBL4850572)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum falcipain-2 expressed in Escherichia coli M15 assessed as reduction in free AMC release using Z-FR-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50578417(CHEMBL4868442)
Affinity DataKi:  2.78E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum falcipain-2 expressed in Escherichia coli M15 assessed as reduction in free AMC release using Z-FR-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50578406(CHEMBL4869807)
Affinity DataKi:  3.32E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum falcipain-2 expressed in Escherichia coli M15 assessed as reduction in free AMC release using Z-FR-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50578405(CHEMBL4856045)
Affinity DataKi:  3.49E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum falcipain-2 expressed in Escherichia coli M15 assessed as reduction in free AMC release using Z-FR-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50578408(CHEMBL4857754)
Affinity DataKi:  4.54E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum falcipain-2 expressed in Escherichia coli M15 assessed as reduction in free AMC release using Z-FR-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50578420(CHEMBL4853187)
Affinity DataKi:  6.91E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum falcipain-2 expressed in Escherichia coli M15 assessed as reduction in free AMC release using Z-FR-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50578418(CHEMBL4871791)
Affinity DataKi:  9.92E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum falcipain-2 expressed in Escherichia coli M15 assessed as reduction in free AMC release using Z-FR-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50463154(CHEMBL4251480)
Affinity DataIC50:  60nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2 using Cbz-Phe-Arg-AMC as substrate measured for 15 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50448248(CHEMBL3120847)
Affinity DataIC50:  80nMAssay Description:Inhibition of Plasmodium falciparum cysteine protease falcipain-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)
Affinity DataIC50:  87nMAssay Description:Inhibition of Cysteine protease falcipain-2 in Plasmodium falciparum HB3 infected erythrocytes by Z-Phe-Arg-AMC substrate hydrolysis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50286441((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...)
Affinity DataIC50:  98nMAssay Description:Inhibition of Cysteine protease falcipain-2 in Plasmodium falciparum HB3-leuR1 mutant infected erythrocytes by Z-Phe-Arg-AMC substrate hydrolysis ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50463146(CHEMBL4240920)
Affinity DataIC50:  190nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2 using Cbz-Phe-Arg-AMC as substrate measured for 15 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50463143(CHEMBL4245127)
Affinity DataIC50:  580nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2 using Cbz-Phe-Arg-AMC as substrate measured for 15 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50448247(CHEMBL3120848)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Plasmodium falciparum cysteine protease falcipain-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50463149(CHEMBL4248915)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2 using Cbz-Phe-Arg-AMC as substrate measured for 15 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50448253(CHEMBL3120842)
Affinity DataIC50:  3.25E+3nMAssay Description:Inhibition of Plasmodium falciparum cysteine protease falcipain-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50578419(CHEMBL4857262)
Affinity DataIC50:  3.38E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum falcipain-2 expressed in Escherichia coli M15 assessed as reduction in free AMC release using Z-FR-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50578421(CHEMBL4850572)
Affinity DataIC50:  3.53E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum falcipain-2 expressed in Escherichia coli M15 assessed as reduction in free AMC release using Z-FR-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50578417(CHEMBL4868442)
Affinity DataIC50:  3.78E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum falcipain-2 expressed in Escherichia coli M15 assessed as reduction in free AMC release using Z-FR-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50448260(CHEMBL3120835)
Affinity DataIC50:  4.42E+3nMAssay Description:Inhibition of Plasmodium falciparum cysteine protease falcipain-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50452180(CHEMBL4211317)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of Plasmodium falciparum FP2 using Z-Leu-Arg-AMC as substrate preincubated for 30 min followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50452177(CHEMBL4207961)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of Plasmodium falciparum FP2 using Z-Leu-Arg-AMC as substrate preincubated for 30 min followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50448261(CHEMBL3120834)
Affinity DataIC50:  5.52E+3nMAssay Description:Inhibition of Plasmodium falciparum cysteine protease falcipain-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50578406(CHEMBL4869807)
Affinity DataIC50:  5.62E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum falcipain-2 expressed in Escherichia coli M15 assessed as reduction in free AMC release using Z-FR-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50578405(CHEMBL4856045)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum falcipain-2 expressed in Escherichia coli M15 assessed as reduction in free AMC release using Z-FR-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50452178(CHEMBL4218177)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of Plasmodium falciparum FP2 using Z-Leu-Arg-AMC as substrate preincubated for 30 min followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM93124(Trisubsituted thiazole, 14)
Affinity DataIC50:  6.60E+3nMAssay Description:In vitro antimalarial assay, antimalarial activity of the compounds was determined in vitro on chloroquine sensitive and resistant strains of plasmod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50452175(CHEMBL4218788)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of Plasmodium falciparum FP2 using Z-Leu-Arg-AMC as substrate preincubated for 30 min followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50550962(CHEMBL4786898)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of Plasmodium falciparum FP-2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50452173(CHEMBL1939368)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of Plasmodium falciparum FP2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50452173(CHEMBL1939368)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of Plasmodium falciparum FP2 using Z-Leu-Arg-AMC as substrate preincubated for 30 min followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50452174(CHEMBL4211543)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of Plasmodium falciparum FP2 using Z-Leu-Arg-AMC as substrate preincubated for 30 min followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50452171(CHEMBL4203015)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of Plasmodium falciparum FP2 using Z-Leu-Arg-AMC as substrate preincubated for 30 min followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50578408(CHEMBL4857754)
Affinity DataIC50:  7.67E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum falcipain-2 expressed in Escherichia coli M15 assessed as reduction in free AMC release using Z-FR-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50452170(CHEMBL4212687)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of Plasmodium falciparum FP2 using Z-Leu-Arg-AMC as substrate preincubated for 30 min followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50452194(CHEMBL4209200)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of Plasmodium falciparum FP2 using Z-Leu-Arg-AMC as substrate preincubated for 30 min followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50578420(CHEMBL4853187)
Affinity DataIC50:  9.38E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum falcipain-2 expressed in Escherichia coli M15 assessed as reduction in free AMC release using Z-FR-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50452176(CHEMBL4213904)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Plasmodium falciparum FP2 using Z-Leu-Arg-AMC as substrate preincubated for 30 min followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50578422(CHEMBL4845812)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant Plasmodium falciparum falcipain-2 expressed in Escherichia coli M15 assessed as reduction in free AMC release using Z-FR-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50452179(CHEMBL4209486)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Plasmodium falciparum FP2 using Z-Leu-Arg-AMC as substrate preincubated for 30 min followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM93130(Trisubsituted thiazole, 29)
Affinity DataIC50: >1.25E+4nMAssay Description:In vitro antimalarial assay, antimalarial activity of the compounds was determined in vitro on chloroquine sensitive and resistant strains of plasmod...More data for this Ligand-Target Pair
In DepthDetails Article
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM93125(Trisubsituted thiazole, 15)
Affinity DataIC50: >1.25E+4nMAssay Description:In vitro antimalarial assay, antimalarial activity of the compounds was determined in vitro on chloroquine sensitive and resistant strains of plasmod...More data for this Ligand-Target Pair
In DepthDetails Article
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50578418(CHEMBL4871791)
Affinity DataIC50:  1.35E+4nMAssay Description:Inhibition of recombinant Plasmodium falciparum falcipain-2 expressed in Escherichia coli M15 assessed as reduction in free AMC release using Z-FR-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM93129(Trisubsituted thiazole, 23)
Affinity DataIC50:  1.53E+4nMAssay Description:In vitro antimalarial assay, antimalarial activity of the compounds was determined in vitro on chloroquine sensitive and resistant strains of plasmod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50578410(CHEMBL4859406)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of recombinant Plasmodium falciparum falcipain-2 expressed in Escherichia coli M15 assessed as reduction in free AMC release using Z-FR-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50463150(CHEMBL4246909)
Affinity DataIC50:  2.68E+4nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2 using Cbz-Phe-Arg-AMC as substrate measured for 15 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50448252(CHEMBL3120843)
Affinity DataIC50:  2.97E+4nMAssay Description:Inhibition of Plasmodium falciparum cysteine protease falcipain-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM50448251(CHEMBL3120844)
Affinity DataIC50:  3.01E+4nMAssay Description:Inhibition of Plasmodium falciparum cysteine protease falcipain-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
India

Curated by ChEMBL
LigandPNGBDBM93128(Trisubsituted thiazole, 20)
Affinity DataIC50: >3.30E+4nMAssay Description:In vitro antimalarial assay, antimalarial activity of the compounds was determined in vitro on chloroquine sensitive and resistant strains of plasmod...More data for this Ligand-Target Pair
In DepthDetails Article
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