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Found 6 Enz. Inhib. hit(s) with Target = 'Dihydropyrimidine dehydrogenase [NADP(+)]'
TargetDihydropyrimidine dehydrogenase [NADP(+)](Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124202(5-Ethynyl-1H-pyrimidine-2,4-dione | CHEMBL355200)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity of the compound against dihydropyrimidine dehydrogenase (DPD)More data for this Ligand-Target Pair
TargetDihydropyrimidine dehydrogenase [NADP(+)](Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124200(5-((E)-Styryl)-1H-pyrimidine-2,4-dione | CHEMBL352...)
Affinity DataIC50:  43nMAssay Description:Inhibitory activity of the compound against dihydropyrimidine dehydrogenase (DPD)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydropyrimidine dehydrogenase [NADP(+)](Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124204(5-Vinyl-1H-pyrimidine-2,4-dione | CHEMBL170188)
Affinity DataIC50:  89nMAssay Description:Inhibitory activity of the compound against dihydropyrimidine dehydrogenase (DPD)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydropyrimidine dehydrogenase [NADP(+)](Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124201(5-(3-Benzyloxy-benzyl)-1H-pyrimidine-2,4-dione | C...)
Affinity DataIC50:  97nMAssay Description:Inhibitory activity of the compound against dihydropyrimidine dehydrogenase (DPD)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydropyrimidine dehydrogenase [NADP(+)](Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124205(2,4-Dioxo-1,2,3,4-tetrahydro-pyrimidine-5-carbonit...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity of the compound against dihydropyrimidine dehydrogenase (DPD)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydropyrimidine dehydrogenase [NADP(+)](Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124203(5-IODOURACIL | 5-Iodo-1H-pyrimidine-2,4-dione | CH...)
Affinity DataIC50:  220nMAssay Description:Inhibitory activity of the compound against dihydropyrimidine dehydrogenase (DPD)More data for this Ligand-Target Pair