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Found 30 Enz. Inhib. hit(s) with Target = 'Glucose-6-phosphatase catalytic subunit 1'
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50103118(CHEMBL66059 | N,N-Dibenzyl-N'-[1-(5-chloro-thiophe...)
Affinity DataIC50:  170nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103125(CHEMBL69115 | N,N-Dibenzyl-N'-[1-(4-methoxy-phenyl...)
Affinity DataIC50:  220nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103111(CHEMBL69665 | N,N-Dibenzyl-N'-[1-(4-chloro-phenyl)...)
Affinity DataIC50:  240nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103119(CHEMBL302504 | N,N-Dibenzyl-N'-[1-(5-ethyl-furan-2...)
Affinity DataIC50:  330nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103107(CHEMBL65842 | N,N-Dibenzyl-N'-[1-(3-methoxy-phenyl...)
Affinity DataIC50:  700nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103128(CHEMBL68984 | N,N-Dibenzyl-N'-[1-furan-2-yl-meth-(...)
Affinity DataIC50:  1.10E+3nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103106(CHEMBL69480 | N,N-Dibenzyl-N'-[1-thiophen-2-yl-met...)
Affinity DataIC50:  1.50E+3nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103122(CHEMBL69334 | N,N-Dibenzyl-N'-[1-phenyl-meth-(E)-y...)
Affinity DataIC50:  1.50E+3nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103110(CHEMBL305258 | N,N-Dibenzyl-N'-[1-(3,4-dichloro-ph...)
Affinity DataIC50:  2.00E+3nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103114(CHEMBL69541 | N,N-Dibenzyl-N'-[1-cyclohexyl-meth-(...)
Affinity DataIC50:  2.40E+3nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103115(4-(Dibenzyl-hydrazonomethyl)-phenol | CHEMBL70032)
Affinity DataIC50:  2.40E+3nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103126(CHEMBL68011 | N,N-Dibenzyl-N'-[1-pyridin-3-yl-meth...)
Affinity DataIC50:  3.70E+3nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50529620(CHEMBL4558600)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of glucose-6-phosphatase in rat H42E cells using glucose-6-phosphate as substrate preincubated overnight followed by substrate addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50529620(CHEMBL4558600)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of glucose-6-phosphatase in rat H42E cells using glucose-6-phosphate as substrate preincubated overnight followed by substrate addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103120(CHEMBL69497 | N,N-Dibenzyl-N'-[1-pyridin-2-yl-meth...)
Affinity DataIC50:  1.00E+4nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50389999(CHEMBL2071306)
Affinity DataIC50:  1.39E+4nMAssay Description:Inhibition of glucose-6-phosphatase enzymatic activity in rat H42E cells using G6P substrate incubated for 18 hrs by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103124(CHEMBL67272 | [5-(Dibenzyl-hydrazonomethyl)-furan-...)
Affinity DataIC50:  1.60E+4nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103112(CHEMBL71650 | N,N-Dibenzyl-N'-[1-pyridin-4-yl-meth...)
Affinity DataIC50:  1.70E+4nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103121(CHEMBL419070 | N,N-Dibenzyl-N'-[1-phenyl-eth-(E)-y...)
Affinity DataIC50:  2.50E+4nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103109(CHEMBL66774 | N,N-Dibenzyl-N'-[3,4-dihydro-2H-naph...)
Affinity DataIC50:  2.50E+4nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103116(CHEMBL68981 | N,N-Dibenzyl-N'-[6-methoxy-3,4-dihyd...)
Affinity DataIC50: >5.00E+4nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50277824(4'-Amino-4-fluoro-2'',4''-dimethoxy-6'-methylsulfa...)
Affinity DataIC50:  7.90E+4nMAssay Description:Inhibition of glucose-6-phosphatase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50294478((E)-4-phenyl-1-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-...)
Affinity DataIC50:  8.70E+4nMAssay Description:Inhibition of rat liver glucose-6-phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50294477((E)-1-(beta-D-glucopyranosyl)-4-(4'-chlorophenyl)b...)
Affinity DataIC50:  8.70E+4nMAssay Description:Inhibition of rat liver glucose-6-phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103113(CHEMBL69758 | [4-(Dibenzyl-hydrazonomethyl)-phenyl...)
Affinity DataIC50:  1.00E+5nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103123(CHEMBL68153 | N,N-Dibenzyl-N'-[2-phenyl-eth-(E)-yl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103117(CHEMBL302496 | N,N-Dibenzyl-N'-[1-(3,5-dichloro-ph...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103127(CHEMBL69742 | N,N-Dibenzyl-N'-[1-(5-nitro-furan-2-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50103108(CHEMBL304503 | N,N-Dibenzyl-N'-[1-(2-methoxy-pheny...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was evaluated for inhibition of Glucose-6-Phosphatase from Triton X-100 disrupted pig liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphatase catalytic subunit 1(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50390000(CHEMBL2071309)
Affinity DataIC50:  3.91E+5nMAssay Description:Inhibition of glucose-6-phosphatase enzymatic activity in rat H42E cells using G6P substrate incubated for 18 hrs by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed