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Found 167 Enz. Inhib. hit(s) with Target = 'Protein Nef'
TargetProtein Nef/Tyrosine-protein kinase HCK(Homo sapiens (Human))
University Of Pittsburgh

LigandPNGBDBM36545(DFP-4APF | diphenylfuropyrimidine-4-aminopropylfur...)
Affinity DataIC50:  2.00E+3nMT: 2°CAssay Description:In vitro kinase activity of Nef-Hck complex and Hck alone using Z'-lyte kinase assay system and Tyr2 peptide substrate from Invitrogen.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Nef/Tyrosine-protein kinase HCK(Homo sapiens (Human))
University Of Pittsburgh

LigandPNGBDBM14807(3-(5,6-Diphenyl-furo[2,3-d]pyrimidin-4-ylamino)-pr...)
Affinity DataIC50:  5.10E+3nMT: 2°CAssay Description:In vitro kinase activity of Nef-Hck complex and Hck alone using Z'-lyte kinase assay system and Tyr2 peptide substrate from Invitrogen.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Nef/Tyrosine-protein kinase HCK(Homo sapiens (Human))
University Of Pittsburgh

LigandPNGBDBM36544(DFP-4AB | Diphenylfuropyrimidine-4-aminobutanol)
Affinity DataIC50:  1.60E+4nMT: 2°CAssay Description:In vitro kinase activity of Nef-Hck complex and Hck alone using Z'-lyte kinase assay system and Tyr2 peptide substrate from Invitrogen.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Nef/Tyrosine-protein kinase HCK(Homo sapiens (Human))
University Of Pittsburgh

LigandPNGBDBM14806(5,6-Diphenyl-furo[2,3-d]pyrimidin-4 -ylamine | 5,6...)
Affinity DataIC50: >3.00E+4nMT: 2°CAssay Description:In vitro kinase activity of Nef-Hck complex and Hck alone using Z'-lyte kinase assay system and Tyr2 peptide substrate from Invitrogen.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288019(US10087178, Example 1)
Affinity DataEC50:  3.10nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288020(US10087178, Example 2)
Affinity DataEC50:  4.20nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288021(US10087178, Example 3)
Affinity DataEC50:  3.20nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288022(US10087178, Example 4)
Affinity DataEC50:  2.90nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288023(US10087178, Example 5)
Affinity DataEC50:  2.90nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288024(US10087178, Example 6)
Affinity DataEC50:  2nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288025(US10087178, Example 7)
Affinity DataEC50:  5nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288027(US10087178, Example 8)
Affinity DataEC50:  8.10nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288028(US10087178, Example 9)
Affinity DataEC50:  5.60nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288029(US10087178, Example 10)
Affinity DataEC50:  3.60nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288030(US10087178, Example 11 | US10087178, Example 15)
Affinity DataEC50:  5.80nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288031(US10087178, Example 12 | US10087178, Example 16)
Affinity DataEC50:  5nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288032(US10087178, Example 13)
Affinity DataEC50:  5.40nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288033(US10087178, Example 14)
Affinity DataEC50:  9.10nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288030(US10087178, Example 11 | US10087178, Example 15)
Affinity DataEC50:  7.20nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288031(US10087178, Example 12 | US10087178, Example 16)
Affinity DataEC50:  6.10nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288036(US10087178, Example 17)
Affinity DataEC50:  3.40nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288037(US10087178, Example 18)
Affinity DataEC50:  2.60nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288038(US10087178, Example 19)
Affinity DataEC50:  4.20nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288039(US10087178, Example 20)
Affinity DataEC50:  20nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288040(US10087178, Example 21)
Affinity DataEC50:  48nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288041(US10087178, Example S1 | trans-3-(benzyloxy)-N-(2,...)
Affinity DataEC50:  7.70nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288042(US10087178, Example S2 | cis-3-(benzyloxy)-N-(2,4-...)
Affinity DataEC50:  10nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288043(N-(2,4-difluorobenzyl)- trans-3,9'-dihydroxy-2'- i...)
Affinity DataEC50:  11nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288044(N-(2,4-difluorobenzyl)-cis- 3,9'-dihydroxy-2'-isop...)
Affinity DataEC50:  4.90nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288045(N-(2,4-difluorobenzyl)-9'- hydroxy-2'-isopropyl-tr...)
Affinity DataEC50:  4.40nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288046(N-(2,4-difluorobenzyl)-9'- hydroxy-2'-isopropyl-ci...)
Affinity DataEC50:  3.70nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288047(N-(2,4-difluorobenzyl)- trans-3-ethoxy-9'-hydroxy-...)
Affinity DataEC50:  3.70nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288048(N-(2,4-difluorobenzyl)-9'- hydroxy-2'-isopropyl-tr...)
Affinity DataEC50:  5.30nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288049(US10087178, Example S9 | trans-3-(benzyloxy)-N-(2,...)
Affinity DataEC50:  5.20nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288050(US10087178, Example S10 | cis-3-(benzyloxy)-N-(2,4...)
Affinity DataEC50:  6.10nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288051(N-(2,4-difluorobenzyl)- trans-3,9'-dihydroxy-2'- m...)
Affinity DataEC50:  25nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288052(N-(2,4-difluorobenzyl)-cis- 3,9'-dihydroxy-2'-meth...)
Affinity DataEC50:  23nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288053(N-(2,4-difluorobenzyl)-9'- hydroxy-trans-3-methoxy...)
Affinity DataEC50:  4.5nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288054(N-(2,4-difluorobenzyl)-9'- hydroxy-cis-3-methoxy-2...)
Affinity DataEC50:  3.90nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288055(US10087178, Example S15 | trans-3-(benzyloxy)-N-(2...)
Affinity DataEC50:  6.90nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288056(US10087178, Example S16 | cis-3-(benzyloxy)-N-(2,4...)
Affinity DataEC50:  7.80nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288057(N-(2,4-difluorobenzyl)-2'- ethyl-trans-3,9'-dihydr...)
Affinity DataEC50:  20nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288058(N-(2,4-difluorobenzyl)-2'- ethyl-cis-3,9'-dihydrox...)
Affinity DataEC50:  16nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288059(N-(2,4-difluorobenzyl)-2'- ethyl-9'-hydroxy-trans-...)
Affinity DataEC50:  4.80nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288060(N-(2,4-difluorobenzyl)-2'- ethyl-9'-hydroxy-cis-3-...)
Affinity DataEC50:  3.5nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288061(N-(2,4-difluorobenzyl)-cis- 3-ethoxy-2'-ethyl-9'- ...)
Affinity DataEC50:  3.80nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288062(N-(2,4-difluorobenzyl)-9'- hydroxy-cis-3- (hydroxy...)
Affinity DataEC50:  5nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288063(N-(2,4-difluorobenzyl)-9'- hydroxy-2'-isopropyl-ci...)
Affinity DataEC50:  6.30nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288064(N-(2,4-difluorobenzyl)-9'- hydroxy-trans-3- (hydro...)
Affinity DataEC50:  16nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288065(N-(2,4-difluorobenzyl)-9'- hydroxy-2'-isopropyl-tr...)
Affinity DataEC50:  7nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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