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Found 5 Enz. Inhib. hit(s) with Target = 'DNA helicase IV'
TargetDNA helicase IV(Escherichia coli (strain K12))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50177710((3-acetylamino-5-oxo-5,11-dihydro-10-thia-dibenzo[...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of ATPase activity of Helicase4 from Escherichia coli in presence of ATP (5x Km(ATP)) and dT25 (5x KDNA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA helicase IV(Escherichia coli (strain K12))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50177713(2-(5-oxo-5,11-dihydro-10-thia-dibenzo[a,d]cyclohep...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of ATPase activity of Helicase4 from Escherichia coli in presence of ATP (5x Km(ATP)) and dT25 (5x KDNA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA helicase IV(Escherichia coli (strain K12))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50177711((5-oxo-5,11-dihydro-10-thia-dibenzo[a,d]cyclohepte...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of ATPase activity of Helicase4 from Escherichia coli in presence of ATP (5x Km(ATP)) and dT25 (5x KDNA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA helicase IV(Escherichia coli (strain K12))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50177711((5-oxo-5,11-dihydro-10-thia-dibenzo[a,d]cyclohepte...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of ATPase activity of Tyr473Ala mutated Helicase4 in presence of ATP (5x Km(ATP)) and dT25 (5x KDNA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA helicase IV(Escherichia coli (strain K12))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50177712((2-methyl-5-oxo-5,11-dihydro-10-thia-dibenzo[a,d]c...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of ATPase activity of Helicase4 from Escherichia coli in presence of ATP (5x Km(ATP)) and dT25 (5x KDNA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed