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Found 35 Enz. Inhib. hit(s) with Target = 'NAD-dependent protein deacetylase HST2'
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50304357(4-(4-ethylphenoxy)-butyric acid 6-oxo-6H-benzo[c]c...)
Affinity DataKi:  1.20E+3nMAssay Description:Noncompetitive inhibition of yeast Hst2 using NAD+ substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50304355(3,4,6-trichloro-2-(2,5-dichloro-6-hydroxy-3-methyl...)
Affinity DataKi:  2.50E+3nMAssay Description:Noncompetitive inhibition of yeast Hst2 using NAD+ substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50304355(3,4,6-trichloro-2-(2,5-dichloro-6-hydroxy-3-methyl...)
Affinity DataKi:  2.50E+3nMAssay Description:Mixed inhibition of yeast Hst2 using Acetyl-lysine substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50304357(4-(4-ethylphenoxy)-butyric acid 6-oxo-6H-benzo[c]c...)
Affinity DataKi:  6.30E+3nMAssay Description:Noncompetitive inhibition of yeast Hst2 using Acetyl-lysine substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50304354(3-(1-Oxo-1,3-dihydro-isoindol-2-yl)-propionic acid...)
Affinity DataKi:  3.00E+4nMAssay Description:Noncompetitive inhibition of yeast Hst2 using NAD+ substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50304354(3-(1-Oxo-1,3-dihydro-isoindol-2-yl)-propionic acid...)
Affinity DataKi:  3.90E+4nMAssay Description:Noncompetitive inhibition of yeast Hst2 using Acetyl-lysine substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50304351(6-methoxy-1-(3-methoxy-prop-1-ynyl)-2-methyl-1,2,3...)
Affinity DataKi:  4.20E+4nMAssay Description:Mixed inhibition of yeast Hst2 using NAD+ substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50304351(6-methoxy-1-(3-methoxy-prop-1-ynyl)-2-methyl-1,2,3...)
Affinity DataKi:  4.30E+4nMAssay Description:Noncompetitive inhibition of yeast Hst2 using Acetyl-lysine substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50178766(2-chloro-5,6,7,8,9,10-hexahydrocyclohepta[b]indole...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50304357(4-(4-ethylphenoxy)-butyric acid 6-oxo-6H-benzo[c]c...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50304355(3,4,6-trichloro-2-(2,5-dichloro-6-hydroxy-3-methyl...)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50304356(2-methyl-5,6,7,8,9,10-hexahydrocyclohepta[b]indole...)
Affinity DataIC50:  1.45E+4nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50304354(3-(1-Oxo-1,3-dihydro-isoindol-2-yl)-propionic acid...)
Affinity DataIC50:  1.99E+4nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50304354(3-(1-Oxo-1,3-dihydro-isoindol-2-yl)-propionic acid...)
Affinity DataIC50:  1.99E+4nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM3175(3-[1-[3-(Amidinothio)propyl]-3-indolyl]-4-(1-methy...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50156760((E)-2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N...)
Affinity DataIC50:  4.80E+4nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM27507(3-Pyridinecarboxamide | CHEMBL1140 | NAM | niacina...)
Affinity DataIC50:  9.10E+4nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM99917(4-tert-butyl-N-(4-(5-(dimethylamino)pentanamido)ph...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50304351(6-methoxy-1-(3-methoxy-prop-1-ynyl)-2-methyl-1,2,3...)
Affinity DataIC50:  1.30E+5nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50336799(5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino...)
Affinity DataIC50:  2.40E+5nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50304352(6-methoxy-2-(4-methoxy-benzyl)-1-(3-methoxy-prop-1...)
Affinity DataIC50:  2.60E+5nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM29590(1,2-Dihydro-3H-naphtho[2,1-b]pyran-3-one | CHEMBL8...)
Affinity DataIC50: >6.00E+5nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50378583(SURFACTIN)
Affinity DataIC50: >7.00E+5nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM29040(cambinol)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of yeast Hst2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50242440((2S)-2-[(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-{...)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to Saccharomyces cerevisiae Hst2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50242439((1-{[(5S)-5-{[(2S)-1-[(2S)-2-{[(1S)-1-{[(1S)-5-ami...)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to Saccharomyces cerevisiae Hst2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50242438((2S)-2-[(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-{...)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to Saccharomyces cerevisiae Hst2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50242437((2S)-2-[(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-{...)
Affinity DataKd:  8.60E+3nMAssay Description:Binding affinity to Saccharomyces cerevisiae Hst2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50242436((2S)-2-[(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-{...)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to Saccharomyces cerevisiae Hst2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50242435((2S)-2-[(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-{...)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to Saccharomyces cerevisiae Hst2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50242442((2S)-2-[(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-{...)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to Saccharomyces cerevisiae Hst2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50242443(CID44560107 | [amino({[(5S)-5-{[(2S)-1-[(2S)-2-{[(...)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to Saccharomyces cerevisiae Hst2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50242433((2S)-2-[(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-{...)
Affinity DataKd:  2.10E+4nMAssay Description:Binding affinity to Saccharomyces cerevisiae Hst2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50242434((2S)-2-[(2S)-6-amino-2-[(2S)-5-carbamimidamido-2-{...)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to Saccharomyces cerevisiae Hst2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase HST2(Saccharomyces cerevisiae)
Institute

Curated by ChEMBL
LigandPNGBDBM50242441((2S)-2-[(2S)-6-amino-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(...)
Affinity DataKd:  1.60E+4nMAssay Description:Binding affinity to Saccharomyces cerevisiae Hst2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed