Affinity DataKi: 1nM ΔG°: -53.4kJ/mole IC50: 5nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nM ΔG°: >-23.7kJ/mole IC50: >1.00E+5nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:The in vitro antiviral activity of the compounds was determined using a cell-based antiviral assay. In this assay, the cytopathic effect (CPE) in Mad...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:The in vitro antiviral activity of the compounds was determined using a cell-based antiviral assay. In this assay, the cytopathic effect (CPE) in Mad...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:The in vitro antiviral activity of the compounds was determined using a cell-based antiviral assay. In this assay, the cytopathic effect (CPE) in Mad...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:The in vitro antiviral activity of the compounds was determined using a cell-based antiviral assay. In this assay, the cytopathic effect (CPE) in Mad...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:The in vitro antiviral activity of the compounds was determined using a cell-based antiviral assay. In this assay, the cytopathic effect (CPE) in Mad...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:The in vitro antiviral activity of the compounds was determined using a cell-based antiviral assay. In this assay, the cytopathic effect (CPE) in Mad...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:The in vitro antiviral activity of the compounds was determined using a cell-based antiviral assay. In this assay, the cytopathic effect (CPE) in Mad...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:The in vitro antiviral activity of the compounds was determined using a cell-based antiviral assay. In this assay, the cytopathic effect (CPE) in Mad...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:The cytopathic effect (CPE) inhibition test is used for measuring the antiviral effect. Monolayer cells in 96-well plates are inoculated with 0.1 ml ...More data for this Ligand-Target Pair
Affinity DataIC50: 43nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:The in vitro antiviral activity of the compounds was determined using a cell-based antiviral assay. In this assay, the cytopathic effect (CPE) in Mad...More data for this Ligand-Target Pair
Affinity DataIC50: 412nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey
US Patent
Rutgers, The State University Of New Jersey
US Patent
Affinity DataIC50: 560nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey
US Patent
Rutgers, The State University Of New Jersey
US Patent
Affinity DataIC50: 560nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
Affinity DataIC50: 893nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey
US Patent
Rutgers, The State University Of New Jersey
US Patent
Affinity DataIC50: 1.10E+3nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
Affinity DataIC50: 1.23E+3nMAssay Description:In vivo inhibition of leutenising hormone in rats.More data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey
US Patent
Rutgers, The State University Of New Jersey
US Patent
Affinity DataIC50: 2.00E+3nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMpH: 5.0Assay Description:Inhibition of hemagglutinin in Influenza A virus (A/X-31(H3N2)) infected in chicken red blood cells assessed as inhibition of hemolysis preincubated ...More data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey
US Patent
Rutgers, The State University Of New Jersey
US Patent
Affinity DataIC50: 3.30E+3nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMpH: 5.0Assay Description:Inhibition of hemagglutinin in Influenza A virus (A/X-31(H3N2)) infected in chicken red blood cells assessed as inhibition of hemolysis preincubated ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of Human influenza virus A/Aichi/2/68 (H3N2) hemagglutinin activity in chicken erythrocytes after 1 hrMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey
US Patent
Rutgers, The State University Of New Jersey
US Patent
Affinity DataIC50: 4.70E+3nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
Affinity DataIC50: 5.29E+3nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
Affinity DataIC50: 6.60E+3nMAssay Description:The cytopathic effect (CPE) inhibition test is used for measuring the antiviral effect. Monolayer cells in 96-well plates are inoculated with 0.1 ml ...More data for this Ligand-Target Pair
Affinity DataIC50: 7.38E+3nMAssay Description:The cytopathic effect (CPE) inhibition test is used for measuring the antiviral effect. Monolayer cells in 96-well plates are inoculated with 0.1 ml ...More data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey
US Patent
Rutgers, The State University Of New Jersey
US Patent
Affinity DataIC50: 7.40E+3nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey
US Patent
Rutgers, The State University Of New Jersey
US Patent
Affinity DataIC50: 7.60E+3nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
Affinity DataIC50: 7.81E+3nMAssay Description:Inhibition of Human influenza virus A/Aichi/2/68 (H3N2) hemagglutinin activity in chicken erythrocytes after 1 hrMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Saitama University
Curated by ChEMBL
Saitama University
Curated by ChEMBL
Affinity DataIC50: 7.81E+3nMAssay Description:Inhibition of Human influenza virus A/PR/8/34 (H1N1) hemagglutinin activity in chicken erythrocytes after 1 hrMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Saitama University
Curated by ChEMBL
Saitama University
Curated by ChEMBL
Affinity DataIC50: 7.81E+3nMAssay Description:Inhibition of Human influenza virus A/PR/8/34 (H1N1) hemagglutinin activity in chicken erythrocytes after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 9.60E+3nMAssay Description:The cytopathic effect (CPE) inhibition test is used for measuring the antiviral effect. Monolayer cells in 96-well plates are inoculated with 0.1 ml ...More data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey
US Patent
Rutgers, The State University Of New Jersey
US Patent
Affinity DataIC50: 1.06E+4nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey
US Patent
Rutgers, The State University Of New Jersey
US Patent
Affinity DataIC50: 1.08E+4nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Saitama University
Curated by ChEMBL
Saitama University
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of Influenza A virus (A/PR 8/34 (H1N1)) hemagglutinin transfected in human HeLa cells assessed as reduction in low pH-indued polykaryon fo...More data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey
US Patent
Rutgers, The State University Of New Jersey
US Patent
Affinity DataIC50: 1.22E+4nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey
US Patent
Rutgers, The State University Of New Jersey
US Patent
Affinity DataIC50: 1.32E+4nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey
US Patent
Rutgers, The State University Of New Jersey
US Patent
Affinity DataIC50: >2.00E+4nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey
US Patent
Rutgers, The State University Of New Jersey
US Patent
Affinity DataIC50: 2.40E+4nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
Affinity DataIC50: 2.67E+4nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey
US Patent
Rutgers, The State University Of New Jersey
US Patent
Affinity DataIC50: 5.30E+4nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain swl A/California/04/2009...)
Rutgers, The State University Of New Jersey
US Patent
Rutgers, The State University Of New Jersey
US Patent
Affinity DataIC50: >1.00E+5nMpH: 7.5Assay Description:The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...More data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of Human influenza virus A/Aichi/2/68 (H3N2) hemagglutinin activity in chicken erythrocytes after 1 hrMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Saitama University
Curated by ChEMBL
Saitama University
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of Human influenza virus A/PR/8/34 (H1N1) hemagglutinin activity in chicken erythrocytes after 1 hrMore data for this Ligand-Target Pair