Compile Data Set for Download or QSAR
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Found 252 Enz. Inhib. hit(s) with Target = 'Delta-type/Kappa-type/Mu-type opioid receptor'
TargetDelta-type/Kappa-type/Mu-type opioid receptor(MOUSE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50474629(CHEMBL415006)
Affinity DataKi:  0.300nMAssay Description:Compound was tested for binding affinity on intact HEK cells using [3H]diprenorphine as radioligand co-expressed with delta and kappa opioid receptor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(MOUSE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50474628(CHEMBL386810)
Affinity DataKi:  0.5nMAssay Description:Compound was tested for binding affinity on intact HEK cells using [3H]diprenorphine as radioligand co-expressed with delta and kappa opioid receptor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(MOUSE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50474624(CHEMBL409172)
Affinity DataKi:  1.10nMAssay Description:Compound was tested for binding affinity on intact HEK cells using [3H]diprenorphine as radioligand singly expressed with delta or kappa receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(MOUSE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50474624(CHEMBL409172)
Affinity DataKi:  1.40nMAssay Description:Compound was tested for binding affinity on intact HEK cells using [3H]diprenorphine as radioligand co-expressed with delta and kappa opioid receptor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(MOUSE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50474626(CHEMBL414603)
Affinity DataKi:  3.30nMAssay Description:Compound was tested for binding affinity on intact HEK cells using [3H]diprenorphine as radioligand singly expressed with delta or kappa receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(MOUSE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50474626(CHEMBL414603)
Affinity DataKi:  4.80nMAssay Description:Compound was tested for binding affinity on intact HEK cells using [3H]diprenorphine as radioligand co-expressed with delta and kappa opioid receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(MOUSE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50474625(CHEMBL611140)
Affinity DataKi:  6.30nMAssay Description:Compound was tested for binding affinity on intact HEK cells using [3H]diprenorphine as radioligand singly expressed with delta or kappa receptors.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(MOUSE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50474627(CHEMBL440626)
Affinity DataKi:  55nMAssay Description:Compound was tested for binding affinity on intact HEK cells using [3H]diprenorphine as radioligand singly expressed with delta or kappa receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(MOUSE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50474628(CHEMBL386810)
Affinity DataKi:  59nMAssay Description:Compound was tested for binding affinity on intact HEK cells using [3H]diprenorphine as radioligand singly expressed with delta or kappa receptors.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(MOUSE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50474629(CHEMBL415006)
Affinity DataKi:  63nMAssay Description:Compound was tested for binding affinity on intact HEK cells using [3H]diprenorphine as radioligand singly expressed with delta or kappa receptors.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(MOUSE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50474623(CHEMBL410574)
Affinity DataKi:  199nMAssay Description:Compound was tested for binding affinity on intact HEK cells using [3H]diprenorphine as radioligand singly expressed with delta or kappa receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(MOUSE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50474625(CHEMBL611140)
Affinity DataKi:  315nMAssay Description:Compound was tested for binding affinity on intact HEK cells using [3H]diprenorphine as radioligand co-expressed with delta and kappa opioid receptor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(MOUSE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50474627(CHEMBL440626)
Affinity DataKi: >1.00E+3nMAssay Description:Compound was tested for binding affinity on intact HEK cells using [3H]diprenorphine as radioligand co-expressed with delta and kappa opioid receptor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(MOUSE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50474623(CHEMBL410574)
Affinity DataKi: >1.00E+3nMAssay Description:Compound was tested for binding affinity on intact HEK cells using [3H]diprenorphine as radioligand co-expressed with delta and kappa opioid receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50187377(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)
Affinity DataKi: >2.00E+3nMAssay Description:Binding affinity to opioid receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Rattus norvegicus (rat))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50536981(CHEMBL4577544)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]bremazocine from opioid receptor in rat brain membranes after 120 mins by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Rattus norvegicus (rat))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50536985(CHEMBL4531345)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]bremazocine from opioid receptor in rat brain membranes after 120 mins by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50225844(CHEMBL56347)
Affinity DataIC50:  0.0700nMAssay Description:Compound was tested for antagonistic activity against opioid receptor in electrically stimulated longitudinal muscle of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50002346(CHEMBL384584 | [D-pro10]Dynorphin A(1-11))
Affinity DataIC50:  0.220nMAssay Description:Tested for opioid receptor agonistic activity in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50226283(CHEMBL172293)
Affinity DataIC50:  0.280nMAssay Description:In vitro inhibitory activity against opioid activity in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123599(ETORPHINE)
Affinity DataIC50:  0.300nMAssay Description:Evaluated the ability to protect against the irreversible antagonism of morphines effects by beta-FNA in guinea pig ileal longitudinal muscle.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50013388(6-Ethyl-3-(1-hydroxy-cyclopropylmethyl)-11,11-dime...)
Affinity DataIC50:  0.5nMAssay Description:In vitro binding affinity against Opioid receptors from bovine caudate nucleus determined in presence of [3H]- bremazocine (0.5 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM60212((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...)
Affinity DataIC50:  0.550nMAssay Description:Displacement of [3H] naloxone from opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50226282(CHEMBL170858)
Affinity DataIC50:  0.590nMAssay Description:In vitro inhibitory activity against opioid activity in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM60212((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...)
Affinity DataIC50:  0.590nMAssay Description:Displacement of [3H] naloxone from opioid receptor (unknown origin) in presence of 100 mM NaClMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50224554(Ethylketazocine)
Affinity DataIC50:  0.600nMAssay Description:Evaluated the ability to protect against the irreversible antagonism of morphines effects by beta-FNA in guinea pig ileal longitudinal muscle.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50497034(CHEMBL3249714)
Affinity DataIC50:  0.700nMAssay Description:Displacement of [3H] naloxone from opioid receptor (unknown origin) in presence of 100 mM NaClMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50497032(CHEMBL3249922)
Affinity DataIC50:  0.800nMAssay Description:Displacement of [3H]naloxone from opioid receptor (unknown origin) by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50497034(CHEMBL3249714)
Affinity DataIC50:  0.910nMAssay Description:Displacement of [3H] naloxone from opioid receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001714(2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1S,2...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of total opioid receptor by displacing 0.5 nM [3H]bremazocine in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50010703(CHEMBL443068 | H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Cys-A...)
Affinity DataIC50:  1.30nMAssay Description:Opioid receptors antagonist activity in smooth-muscle tissue of guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50059841((S)-1-[(S)-2-[2-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hy...)
Affinity DataIC50:  1.40nMAssay Description:In vitro opioid inhibitory activity against in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50013388(6-Ethyl-3-(1-hydroxy-cyclopropylmethyl)-11,11-dime...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of 0.5 nM [3H]bremazocine binding to guinea pig brain membrane opioid receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50013388(6-Ethyl-3-(1-hydroxy-cyclopropylmethyl)-11,11-dime...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of total opioid receptor by displacing 0.5 nM [3H]bremazocine in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50002184(CHEMBL415330 | H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-A...)
Affinity DataIC50:  1.70nMAssay Description:Opioid receptors antagonist activity in smooth-muscle tissue of guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123599(ETORPHINE)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of total opioid receptor by displacing 0.5 nM [3H]bremazocine in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50010701(CHEMBL410616 | H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-D-Cys...)
Affinity DataIC50:  1.80nMAssay Description:Opioid receptors antagonist activity in smooth-muscle tissue of guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Rattus norvegicus (rat))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50367061(NALORPHINE | NALORPHINE HYDROCHLORIDE)
Affinity DataIC50:  2nMAssay Description:Displacement of [3H]-naloxone from rat opioid receptor after 30 mins by liquid scintillation counting analysis in absence of NaClMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50226284(CHEMBL170091)
Affinity DataIC50:  2.10nMAssay Description:In vitro inhibitory activity against opioid activity in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50002347(CHEMBL425806 | [N-cyclopropyl methylTyr1, D-pro10]...)
Affinity DataIC50:  2.20nMAssay Description:Tested for opioid receptor agonistic activity in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50455774(CHEMBL2092986)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of total opioid receptor by displacing 0.5 nM [3H]bremazocine in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50010706(CHEMBL384250 | H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-D-Cys...)
Affinity DataIC50:  2.30nMAssay Description:Opioid receptors antagonist activity in smooth-muscle tissue of guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001713(CHEMBL143815 | methyl 2-[19-(1-hydroxy-1-methylbut...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of total opioid receptor by displacing 0.5 nM [3H]bremazocine in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50013385(CHEMBL166355 | methyl 2-[4-cyclopropylmethyl-10,17...)
Affinity DataIC50:  2.40nMAssay Description:In vitro binding affinity against Opioid receptors from bovine caudate nucleus determined in presence of [3H]- bremazocine (0.5 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50010702(CHEMBL411557 | DYNORPHIN(1-17)-OH | Dynorphin A (1...)
Affinity DataIC50:  2.5nMAssay Description:Opioid receptors antagonist activity in smooth-muscle tissue of guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataIC50:  2.60nMAssay Description:Tested for opioid receptor agonistic activity in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50226289(CHEMBL369354)
Affinity DataIC50:  2.70nMAssay Description:In vitro opioid inhibitory activity against in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50497036(CHEMBL3249715)
Affinity DataIC50:  2.90nMAssay Description:Displacement of [3H] naloxone from opioid receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50226286(CHEMBL296148)
Affinity DataIC50:  3nMAssay Description:In vitro opioid inhibitory activity against in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Rattus norvegicus (rat))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50497135(CHEMBL3275470)
Affinity DataIC50:  3.40nMAssay Description:Displacement of [3H]-naloxone from rat opioid receptor after 30 mins by liquid scintillation counting analysis in absence of NaClMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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