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Found 92 Enz. Inhib. hit(s) with Target = 'Ribonuclease pancreatic'
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50342010(5'-phospho-2'-deoxyuridine-3'-pyrophosphate(P'->5'...)
Affinity DataKi:  27nMpH: 5.9Assay Description:Inhibition of bovine pancreatic RNase A at pH 5.9 by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Homo sapiens (Human))
Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50292713(5'-phospho-2'-deoxyuridine 3-pyrophosphate (P'->5'...)
Affinity DataKi:  27nMAssay Description:Inhibition of RNase AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Homo sapiens (Human))
Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50402338(CHEMBL401150)
Affinity DataKi:  27nMAssay Description:Inhibition of RNase AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50292721(CHEMBL504858 | [({[(2R,3S,4R,5R)-5-(6-amino-9H-pur...)
Affinity DataKi:  41nMAssay Description:Inhibition of bovine pancreatic RNase A by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50402337(CHEMBL2206660)
Affinity DataKi:  240nMAssay Description:Inhibition of bovine pancreatic RNase AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50292724(CHEMBL460901 | URACIL ARABINOSE-3'-PHOSPHATE | ara...)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of bovine pancreatic RNase A by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50298711((2R,3R,4R,5R)-2-(4-amino-2-oxopyrimidin-1(2H)-yl)-...)
Affinity DataKi:  7.00E+3nMAssay Description:Competitive inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails PubMedMMDB

TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50298711((2R,3R,4R,5R)-2-(4-amino-2-oxopyrimidin-1(2H)-yl)-...)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of bovine pancreatic RNase A by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50292723((2R,3R,4R,5R)-2-(2,4-dioxo-3,4-dihydropyrimidin-1(...)
Affinity DataKi:  7.10E+3nMAssay Description:Inhibition of bovine pancreatic RNase A by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50292723((2R,3R,4R,5R)-2-(2,4-dioxo-3,4-dihydropyrimidin-1(...)
Affinity DataKi:  1.16E+4nMpH: 6.0Assay Description:Inhibition of bovine pancreatic ribonuclease A assessed as enzyme activity by spectrophotometric method pH 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50590733(CHEMBL5174041)
Affinity DataKi:  1.20E+4nMAssay Description:Competitive inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRibonuclease pancreatic(Homo sapiens (Human))
Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50375418(CHEMBL408119)
Affinity DataKi:  1.32E+4nMAssay Description:Activity at RNase AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50233301(CHEMBL258728 | cytidine-3'-monophosphate)
Affinity DataKi:  2.01E+4nMpH: 6.0Assay Description:Inhibition of bovine pancreatic ribonuclease A assessed as enzyme activity by spectrophotometric method pH 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50162334(5-[3-carboxy-4-(3-nitrophenylcarboxamido)benzyl]-2...)
Affinity DataKi:  2.10E+4nMAssay Description:Inhibition of bovine pancreatic RNase A assessed as reduction in CpG cleavage by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50438455(CHEMBL2414522)
Affinity DataKi:  2.50E+4nMAssay Description:Reversible competitive inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50590732(CHEMBL5195359)
Affinity DataKi:  2.80E+4nMAssay Description:Competitive inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50590723(CHEMBL5174669)
Affinity DataKi:  2.90E+4nMAssay Description:Inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50590725(CHEMBL5170654)
Affinity DataKi:  3.20E+4nMAssay Description:Inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50590730(CHEMBL5179731)
Affinity DataKi:  3.20E+4nMAssay Description:Competitive inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50331790(3-Amino-N-[2-hydroxymethyl-5-(5-methyl-2,4-dioxo-3...)
Affinity DataKi:  3.70E+4nMAssay Description:Competitive inhibition of bovine pancreatic RNase A ribonucleolytic activity of by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50438453(CHEMBL2414524)
Affinity DataKi:  3.90E+4nMAssay Description:Reversible competitive inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Homo sapiens (Human))
Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50375420(CHEMBL266234)
Affinity DataKi:  4.20E+4nMAssay Description:Activity at RNase AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50590731(CHEMBL5205517)
Affinity DataKi:  4.40E+4nMAssay Description:Competitive inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM173610(9-[3'-[4-[(Uracil-1-yl)methyl]-1,2,3-triazol-1...)
Affinity DataKi:  5.55E+4nM ΔG°:  -24.7kJ/moleT: 2°CAssay Description:The Ribonuclease Activity assay used was adapted from the procedure described by Anfinsen et al. and Slifman et al. Determination of ribonuclease act...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50590729(CHEMBL5179790)
Affinity DataKi:  6.00E+4nMAssay Description:Competitive inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50342006(5'-Deoxy-5'-N-(4-carboxypiperidinyl)uridine | CHEM...)
Affinity DataKi:  6.10E+4nMAssay Description:Inhibition of bovine pancreatic RNase A using 2',3'-cCMP as a substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50590724(CHEMBL5202511)
Affinity DataKi:  6.67E+4nMAssay Description:Inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50331791((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydr...)
Affinity DataKi:  6.70E+4nMAssay Description:Competitive inhibition of bovine pancreatic RNase A ribonucleolytic activity of by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM173614(9-[3'-[4-[(Thymine-1-yl)methyl]-1,2,3-triazol-...)
Affinity DataKi:  6.88E+4nM ΔG°:  -24.2kJ/moleT: 2°CAssay Description:The Ribonuclease Activity assay used was adapted from the procedure described by Anfinsen et al. and Slifman et al. Determination of ribonuclease act...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50342006(5'-Deoxy-5'-N-(4-carboxypiperidinyl)uridine | CHEM...)
Affinity DataKi:  7.50E+4nMAssay Description:Inhibition of bovine pancreatic RNase A using 2',3'-cCMP as a substrate by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50292715(5'-deoxy-5'-N-(ethyl isonipecotatyl)uridine | CHEM...)
Affinity DataKi:  7.70E+4nMAssay Description:Inhibition of bovine pancreatic RNase A by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50292722(3'-UMP | 3'-uridylic acid | CHEMBL460741)
Affinity DataKi:  7.85E+4nMpH: 6.0Assay Description:Inhibition of bovine pancreatic ribonuclease A assessed as enzyme activity by spectrophotometric method pH 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50590728(CHEMBL5198110)
Affinity DataKi:  7.90E+4nMAssay Description:Competitive inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50298713(2',3'-Dideoxy-3'-L-serinylamino thymidine | CHEMBL...)
Affinity DataKi:  8.00E+4nMAssay Description:Inhibition of bovine pancreatic RNase A by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Homo sapiens (Human))
Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM111444(Ser-aT (Compound 2))
Affinity DataKi:  8.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50292722(3'-UMP | 3'-uridylic acid | CHEMBL460741)
Affinity DataKi:  8.20E+4nMAssay Description:Inhibition of bovine pancreatic RNase A by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50438456(CHEMBL2414521)
Affinity DataKi:  8.80E+4nMAssay Description:Reversible competitive inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50438454(CHEMBL2414523)
Affinity DataKi:  9.30E+4nMAssay Description:Reversible competitive inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50438451(CHEMBL2414510)
Affinity DataKi:  9.50E+4nMAssay Description:Reversible competitive inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Homo sapiens (Human))
Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50375419(CHEMBL259808)
Affinity DataKi:  9.50E+4nMAssay Description:Activity at RNase AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM173612(9-[3'-[4-[(Cytosine-1-yl)methyl]-1,2,3-triazol...)
Affinity DataKi:  9.85E+4nM ΔG°:  -23.3kJ/moleT: 2°CAssay Description:The Ribonuclease Activity assay used was adapted from the procedure described by Anfinsen et al. and Slifman et al. Determination of ribonuclease act...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50233301(CHEMBL258728 | cytidine-3'-monophosphate)
Affinity DataKi:  1.03E+5nMAssay Description:Inhibition of bovine pancreatic RNase A by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50233301(CHEMBL258728 | cytidine-3'-monophosphate)
Affinity DataKi:  1.03E+5nMAssay Description:Inhibition of bovine pancreatic RNase A by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetRibonuclease pancreatic(Homo sapiens (Human))
Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50233301(CHEMBL258728 | cytidine-3'-monophosphate)
Affinity DataKi:  1.03E+5nMAssay Description:Activity at RNase AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Homo sapiens (Human))
Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50276039(1-[3-(4-CARBOXYPIPERIDIN-1-YL)-3-DEOXY-BETA-D-ARAB...)
Affinity DataKi:  1.03E+5nMAssay Description:Inhibition of ribonucleolytic activity of RNase A (unknown origin) by agarose gel based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50292714(3'-N-piperidine-4-carboxyl-3'-deoxyara-uridine | C...)
Affinity DataKi:  1.03E+5nMAssay Description:Inhibition of bovine pancreatic RNase A by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM173613(9-[3'-[4-[(Uracil-1-yl)methyl]-1,2,3-triazol-1...)
Affinity DataKi:  1.06E+5nM ΔG°:  -23.1kJ/moleT: 2°CAssay Description:The Ribonuclease Activity assay used was adapted from the procedure described by Anfinsen et al. and Slifman et al. Determination of ribonuclease act...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50438452(CHEMBL2414509)
Affinity DataKi:  1.08E+5nMAssay Description:Reversible competitive inhibition of bovine pancreatic RNase A using 2',3'-cCMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Homo sapiens (Human))
Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50276040(3'-[1-(4-ethoxycarbonylpiperdinyl)]-3'-deoxy-ara-u...)
Affinity DataKi:  1.20E+5nMAssay Description:Inhibition of ribonucleolytic activity of RNase A (unknown origin) by agarose gel based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease pancreatic(Bison bison (American bison))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50342007(5'-Deoxy-5'-N-(4-carboxypiperidinyl)thymidine | CH...)
Affinity DataKi:  1.21E+5nMAssay Description:Inhibition of bovine pancreatic RNase A using 2',3'-cCMP as a substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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