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Found 31 Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein phosphatase mu'
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054344(CHEMBL3319356 | US9522881, 11a-1 L97M74 | US984453...)
Affinity DataIC50:  3.30E+3nMAssay Description:For selectivity studies, the PTPs, including LYP, mPTPA, SHP1-D1C, PTP1B, LMPTP, VHR, Laforin and PTPα-D1D2 were expressed and purified from E. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054344(CHEMBL3319356 | US9522881, 11a-1 L97M74 | US984453...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of PTPmu (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50436358(CHEMBL2396718)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of recombinant PTPmu (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM231167(US9340574, 7)
Affinity DataIC50: >1.00E+4nMpH: 7.0Assay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in 3,3-dimethylglutarate buffer (50 mM 3,3-dimethylglutarate, pH 7.0, 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50607111(CHEMBL5218807)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PTPmu (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50436357(CHEMBL2396719)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of recombinant PTPmu (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50262987(CHEMBL506661 | Illudalic acid)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of PTPmu (unknown origin) using DiFMUP as substrate incubated for 30 mins followed by substrate addition at pH 6.5 by standard phosphatase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50262987(CHEMBL506661 | Illudalic acid)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of PTPmu (unknown origin) using DiFMUP as substrate incubated for 30 mins followed by substrate addition at pH 6.5 by standard phosphatase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PTPM (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50544431(CHEMBL4637459 | US11192850, Entry 4k)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PTPM (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50112356(CHEMBL3609373)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human PTPmu using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50112358(CHEMBL3609374)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human PTPmu using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50112357(CHEMBL3609375)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human PTPmu using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50544427(CHEMBL4632818 | US11192850, Entry 4g)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of PTPM (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50558485(CHEMBL4800195)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of His-tagged PTPmu (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50607110(CHEMBL5219519)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PTPmu (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50263036(3-Hydroxy-6-methoxy-8,8-dimethyl-1-oxo-1,3,4,7,8,9...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PTPmu (unknown origin) using DiFMUP as substrate incubated for 30 mins followed by substrate addition at pH 6.5 by standard phosphatase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50263036(3-Hydroxy-6-methoxy-8,8-dimethyl-1-oxo-1,3,4,7,8,9...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PTPmu (unknown origin) using DiFMUP as substrate incubated for 30 mins followed by substrate addition at pH 6.5 by standard phosphatase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50558461(CHEMBL4760367)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of His-tagged PTPmu (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50558484(CHEMBL4748824)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged PTPmu (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50558483(CHEMBL4778085)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged PTPmu (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50558482(CHEMBL4742123)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged PTPmu (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50558481(CHEMBL4783639)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged PTPmu (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of PTPmu (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50420258(CEFSULODIN)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of phosphatase activity of human PTPmu using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged PTPmu (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50558487(CHEMBL4786243)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged PTPmu (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50558486(CHEMBL4797766)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged PTPmu (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50188784(CHEMBL385251 | ammonium N-{4-[3-methoxy-2-(methoxy...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of HPTP muMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50188779(CHEMBL378423 | ammonium N-{4-[4-ethoxy-2,2-bis(met...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of HPTP muMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50188777(CHEMBL213452 | ammonium N-[4-(2-{[(benzyloxy)carbo...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of HPTP muMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed