Compile Data Set for Download or QSAR
maximum 50k data
Found 146 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase LATS2'
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM573884(US11458138, Example 4)
Affinity DataIC50:  1nMAssay Description:Human LATS2 kinase domain protein was purchased from Carnabio (catalogue number 01-124), which harbors the catalytic domain of amino acids 553-1088, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM574231(US11458138, Example 62)
Affinity DataIC50:  2nMAssay Description:Human LATS2 kinase domain protein was purchased from Carnabio (catalogue number 01-124), which harbors the catalytic domain of amino acids 553-1088, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM574216(US11458138, Example 48a)
Affinity DataIC50:  2nMAssay Description:Human LATS2 kinase domain protein was purchased from Carnabio (catalogue number 01-124), which harbors the catalytic domain of amino acids 553-1088, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of human LATS2 using KKRNRRLSVA as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM574304(US11458138, Example 133)
Affinity DataIC50:  4nMAssay Description:Human LATS2 kinase domain protein was purchased from Carnabio (catalogue number 01-124), which harbors the catalytic domain of amino acids 553-1088, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM574381(US11458138, Example 261)
Affinity DataIC50:  4nMAssay Description:Human LATS2 kinase domain protein was purchased from Carnabio (catalogue number 01-124), which harbors the catalytic domain of amino acids 553-1088, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM574228(US11458138, Example 59)
Affinity DataIC50:  4nMAssay Description:Human LATS2 kinase domain protein was purchased from Carnabio (catalogue number 01-124), which harbors the catalytic domain of amino acids 553-1088, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM574215(US11458138, Example 47)
Affinity DataIC50:  6nMAssay Description:Human LATS2 kinase domain protein was purchased from Carnabio (catalogue number 01-124), which harbors the catalytic domain of amino acids 553-1088, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM573896(US11458138, Example 6)
Affinity DataIC50:  8nMAssay Description:Human LATS2 kinase domain protein was purchased from Carnabio (catalogue number 01-124), which harbors the catalytic domain of amino acids 553-1088, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM574410(US11458138, Example 290)
Affinity DataIC50:  8nMAssay Description:Human LATS2 kinase domain protein was purchased from Carnabio (catalogue number 01-124), which harbors the catalytic domain of amino acids 553-1088, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of human LATS2 using KKRNRRLSVA as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM574235(US11458138, Example 66)
Affinity DataIC50:  11nMAssay Description:Human LATS2 kinase domain protein was purchased from Carnabio (catalogue number 01-124), which harbors the catalytic domain of amino acids 553-1088, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM574175(US11458138, Example 11)
Affinity DataIC50:  12nMAssay Description:Human LATS2 kinase domain protein was purchased from Carnabio (catalogue number 01-124), which harbors the catalytic domain of amino acids 553-1088, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM574407(US11458138, Example 287)
Affinity DataIC50:  15nMAssay Description:Human LATS2 kinase domain protein was purchased from Carnabio (catalogue number 01-124), which harbors the catalytic domain of amino acids 553-1088, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM574176(US11458138, Example 12)
Affinity DataIC50:  15nMAssay Description:Human LATS2 kinase domain protein was purchased from Carnabio (catalogue number 01-124), which harbors the catalytic domain of amino acids 553-1088, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM574217(US11458138, Example 48b)
Affinity DataIC50:  18nMAssay Description:Human LATS2 kinase domain protein was purchased from Carnabio (catalogue number 01-124), which harbors the catalytic domain of amino acids 553-1088, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM574310(US11458138, Example 139)
Affinity DataIC50:  20nMAssay Description:Human LATS2 kinase domain protein was purchased from Carnabio (catalogue number 01-124), which harbors the catalytic domain of amino acids 553-1088, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM574218(US11458138, Example 49)
Affinity DataIC50:  21nMAssay Description:Human LATS2 kinase domain protein was purchased from Carnabio (catalogue number 01-124), which harbors the catalytic domain of amino acids 553-1088, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM574234(US11458138, Example 65)
Affinity DataIC50:  30nMAssay Description:Human LATS2 kinase domain protein was purchased from Carnabio (catalogue number 01-124), which harbors the catalytic domain of amino acids 553-1088, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM574272(US11458138, Example 101)
Affinity DataIC50:  30nMAssay Description:Human LATS2 kinase domain protein was purchased from Carnabio (catalogue number 01-124), which harbors the catalytic domain of amino acids 553-1088, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM574408(US11458138, Example 288)
Affinity DataIC50:  34nMAssay Description:Human LATS2 kinase domain protein was purchased from Carnabio (catalogue number 01-124), which harbors the catalytic domain of amino acids 553-1088, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM574357(US11458138, Example 186)
Affinity DataIC50:  50nMAssay Description:Human LATS2 kinase domain protein was purchased from Carnabio (catalogue number 01-124), which harbors the catalytic domain of amino acids 553-1088, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM574178(US11458138, Example 14)
Affinity DataIC50:  50nMAssay Description:Human LATS2 kinase domain protein was purchased from Carnabio (catalogue number 01-124), which harbors the catalytic domain of amino acids 553-1088, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM574227(US11458138, Example 58)
Affinity DataIC50:  170nMAssay Description:Human LATS2 kinase domain protein was purchased from Carnabio (catalogue number 01-124), which harbors the catalytic domain of amino acids 553-1088, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM311267((S)-1-((2′,6-bis(difluoromethyl)-[2,4′...)
Affinity DataIC50:  660nMAssay Description:Inhibition of LATS2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM50135286(CHEMBL3745885)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human LATS2 using [KKRNRRLSVA] as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)
Affinity DataKd:  1nMAssay Description:Binding affinity to LATS2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM50326053(CHEMBL608533 | PKC-412)
Affinity DataKd:  2.20E+3nMAssay Description:Binding affinity to LATS2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)
Affinity DataKd:  1nMAssay Description:Binding constant for LATS2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)
Affinity DataKd:  380nMAssay Description:Binding constant for LATS2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataKd:  17nMAssay Description:Binding constant for LATS2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM50326053(CHEMBL608533 | PKC-412)
Affinity DataKd:  2.20E+3nMAssay Description:Binding constant for LATS2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataKd:  17nMAssay Description:Binding constant for LATS2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM50326053(CHEMBL608533 | PKC-412)
Affinity DataKd:  2.20E+3nMAssay Description:Binding constant for LATS2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)
Affinity DataKd:  460nMAssay Description:Binding affinity to LATS2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to LATS2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to LATS2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM50326054(CHEMBL1240703)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to LATS2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM13535(4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to LATS2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for LATS2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM6568(6-(2,6-dichlorophenyl)-8-methyl-2-{[3-(methylsulfa...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for LATS2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM26300(2-{3-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}qu...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for LATS2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for LATS2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM25121(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for LATS2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM60589(6-{[6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for LATS2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM60665(BDBM50249542 | US9145414, R406 | US9212178, R406)
Affinity DataKd:  4.00E+3nMAssay Description:Binding constant for LATS2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for LATS2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM50332294(CHEMBL1287853 | N-tert-butyl-3-(5-methyl-2-(4-(2-(...)
Affinity DataKd:  8.00E+3nMAssay Description:Binding constant for LATS2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM24773(AMG 706 | AMG-706 | Motesanib | N-(3,3-dimethyl-1,...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for LATS2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase LATS2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for LATS2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 146 total ) | Next | Last >>
Jump to: