TargetSodium/hydrogen exchanger 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Compound is screened in AP1 cells expressing human NHE-2 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.90E+3nMAssay Description:In vitro concentration of compound required to inhibit NHE-2 mediated intracellular maximal pH recovery by 50%More data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human NHE2 expressed in Ap1 cell lineMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 9.20E+3nMAssay Description:In vitro concentration of compound required to inhibit NHE-2 mediated intracellular maximal pH recovery by 50%More data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:In vitro concentration of compound required to inhibit NHE-2 mediated intracellular maximal pH recovery by 50%More data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.28E+4nMAssay Description:In vitro concentration of compound required to inhibit NHE-2 mediated intracellular maximal pH recovery by 50%More data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.63E+4nMAssay Description:In vitro concentration of compound required to inhibit NHE-2 mediated intracellular maximal pH recovery by 50%More data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Compound is screened in AP1 cells expressing human NHE-2 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human NHE2 expressed in Ap1 cell lineMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.87E+4nMAssay Description:In vitro concentration of compound required to inhibit NHE-2 mediated intracellular maximal pH recovery by 50%More data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of human NHE2 expressed in Ap1 cell lineMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 6.20E+4nMAssay Description:Compound is screened in AP1 cells expressing human NHE-2 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human NHE2 expressed in LAP1 cell assessed as intracellular pH recovery measured for 2 mins by CECF-AM dye based FLIPR assayMore data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.16E+5nMAssay Description:In vitro concentration of compound required to inhibit NHE-2 mediated intracellular maximal pH recovery by 50%More data for this Ligand-Target Pair