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Found 35 Enz. Inhib. hit(s) with Target = 'Triosephosphate isomerase'
TargetTriosephosphate isomerase(Oryctolagus cuniculus)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50167777(2-(hydroxyamino)-2-oxoethyl dihydrogen phosphate |...)
Affinity DataKi:  3.00E+3nMAssay Description:Binding affinity against rabbit muscle triose-phosphate isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTriosephosphate isomerase(Homo sapiens (Human))
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50167777(2-(hydroxyamino)-2-oxoethyl dihydrogen phosphate |...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of triosephosphate isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTriosephosphate isomerase(Homo sapiens (Human))
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50167777(2-(hydroxyamino)-2-oxoethyl dihydrogen phosphate |...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of Triosephosphate isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTriosephosphate isomerase(Oryctolagus cuniculus)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50167775((Z)-2-amino-2-(hydroxyimino)ethyl hydrogen phospha...)
Affinity DataKi:  4.50E+3nMAssay Description:Binding affinity against rabbit muscle triose-phosphate isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTriosephosphate isomerase(Homo sapiens (Human))
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50167775((Z)-2-amino-2-(hydroxyimino)ethyl hydrogen phospha...)
Affinity DataKi:  4.50E+3nMAssay Description:Inhibition of triosephosphate isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTriosephosphate isomerase(Homo sapiens (Human))
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50113828(CHEMBL311322 | {1-[1-(1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataKi:  1.50E+4nMAssay Description:Binding affinity against Triosephosphate isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTriosephosphate isomerase(Homo sapiens (Human))
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50167772(2-hydrazinyl-2-oxoethyl hydrogen phosphate | CHEMB...)
Affinity DataKi:  1.11E+5nMAssay Description:Inhibition of triosephosphate isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTriosephosphate isomerase(Oryctolagus cuniculus)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50167772(2-hydrazinyl-2-oxoethyl hydrogen phosphate | CHEMB...)
Affinity DataKi:  1.11E+5nMAssay Description:Binding affinity against rabbit muscle triose-phosphate isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTriosephosphate isomerase(Oryctolagus cuniculus)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50167776((2-Hydroxycarbamoyl-ethyl)-phosphonic acid | 3-(hy...)
Affinity DataKi:  1.59E+5nMAssay Description:Binding affinity against rabbit muscle triose-phosphate isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTriosephosphate isomerase(Homo sapiens (Human))
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50167776((2-Hydroxycarbamoyl-ethyl)-phosphonic acid | 3-(hy...)
Affinity DataKi:  1.60E+5nMAssay Description:Inhibition of triosephosphate isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTriosephosphate isomerase(Homo sapiens (Human))
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50198029(CHEMBL390655 | hydrogen [1-azaniumyl-2-(hydroxycar...)
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of triosephosphate isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTriosephosphate isomerase(Homo sapiens (Human))
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50198028(hydrogen 1-hydroxy-3-(hydroxyamino)-3-oxopropylpho...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of triosephosphate isomeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTriosephosphate isomerase, glycosomal(Trypanosoma cruzi)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50597993(ANETHOLTRITHION | Anethole Trithione | Anethole tr...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of Trypanosoma cruzi TIM expressed in Escherichia coli using glyceraldehyde 3-phosphate as substrate in presence of NADH/alphaGDPH measure...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTriosephosphate isomerase, glycosomal(Trypanosoma cruzi)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50597988(CHEMBL5192352)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi TIMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTriosephosphate isomerase, glycosomal(Trypanosoma cruzi)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50597987(CHEMBL5170853)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi TIMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTriosephosphate isomerase, glycosomal(Trypanosoma cruzi)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50332795(3-(4-methylphenyl)-5-oxo-4,5-dihydro-1,2,4-thiadia...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi triosephosphate isomerase after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTriosephosphate isomerase, glycosomal(Trypanosoma cruzi)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50332795(3-(4-methylphenyl)-5-oxo-4,5-dihydro-1,2,4-thiadia...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi TIMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTriosephosphate isomerase, glycosomal(Trypanosoma cruzi)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50597990(CHEMBL3990589)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of recombinant Trypanosoma cruzi TIM using glyceraldehyde 3-phosphate as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTriosephosphate isomerase, glycosomal(Trypanosoma cruzi)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50332796(5-phenyl-1,3,4-oxathiazol-2-one | CHEMBL1632533)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi triosephosphate isomerase after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTriosephosphate isomerase, glycosomal(Trypanosoma cruzi)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50597994(CHEMBL5172018)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of Trypanosoma cruzi TIM expressed in Escherichia coli using glyceraldehyde 3-phosphate as substrate in presence of NADH/alphaGDPH measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTriosephosphate isomerase, glycosomal(Trypanosoma cruzi)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50332793(2,6-Dibenzyl-4-(5-nitro-furan-2-ylm ethylene)-1,1-...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of Trypanosoma cruzi triosephosphate isomerase after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTriosephosphate isomerase, glycosomal(Trypanosoma cruzi)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50597991(CHEMBL5198783)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of Trypanosoma cruzi TIM expressed in Escherichia coli using glyceraldehyde 3-phosphate as substrate preincubated for 2 hrs in presence of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTriosephosphate isomerase, glycosomal(Trypanosoma cruzi)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50332792(4-(5-Nitro-furan-2-ylmethylene)-1,1-dioxo-1,4-dihy...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi triosephosphate isomerase after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTriosephosphate isomerase, glycosomal(Trypanosoma cruzi)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50332794(2,3-dichloro-7-hydroxyphenazine5,10-dioxide | 7,8-...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of Trypanosoma cruzi triosephosphate isomerase after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTriosephosphate isomerase, glycosomal(Trypanosoma cruzi)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50597992(CHEMBL5169735)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of Trypanosoma cruzi TIM expressed in Escherichia coli using glyceraldehyde 3-phosphate as substrate preincubated for 2 hrs in presence of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTriosephosphate isomerase, glycosomal(Trypanosoma cruzi)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50597989(CHEMBL1161789)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of recombinant Trypanosoma cruzi TIM using glyceraldehyde 3-phosphate as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTriosephosphate isomerase, glycosomal(Trypanosoma brucei)
Universidad De La Republica

LigandPNGBDBM246598(TIM inhibitor, 3)
Affinity DataIC50:  3.40E+4nMpH: 7.4 T: 2°CAssay Description:The reaction mixture (1 mL, pH 7.4) contained 100mM triethanolamine, 10mM EDTA, 0.2mM NADH, 1mM glyceraldehyde 3-phosphate (GAP) and 0.9 units of a-g...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTriosephosphate isomerase, glycosomal(Trypanosoma cruzi)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50534545(CHEMBL4576576)
Affinity DataIC50:  7.70E+4nMAssay Description:Inhibition of recombinant Trypanosoma cruzi triosephosphate isomerase assessed as reduction of DHAP after 2 hrs by measuring NADH consumption by alph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTriosephosphate isomerase, glycosomal(Trypanosoma cruzi)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50534546(CHEMBL4462472)
Affinity DataIC50:  8.20E+4nMAssay Description:Inhibition of recombinant Trypanosoma cruzi triosephosphate isomerase assessed as reduction of DHAP after 2 hrs by measuring NADH consumption by alph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTriosephosphate isomerase(Homo sapiens (Human))
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM246596(TIM inhibitor, 1)
Affinity DataIC50:  1.00E+5nMpH: 7.4 T: 2°CAssay Description:The reaction mixture (1 mL, pH 7.4) contained 100mM triethanolamine, 10mM EDTA, 0.2mM NADH, 1mM glyceraldehyde 3-phosphate (GAP) and 0.9 units of a-g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTriosephosphate isomerase(Homo sapiens (Human))
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM246598(TIM inhibitor, 3)
Affinity DataIC50: >1.00E+5nMpH: 7.4 T: 2°CAssay Description:The reaction mixture (1 mL, pH 7.4) contained 100mM triethanolamine, 10mM EDTA, 0.2mM NADH, 1mM glyceraldehyde 3-phosphate (GAP) and 0.9 units of a-g...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTriosephosphate isomerase(Homo sapiens (Human))
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM246597(TIM inhibitor, 2)
Affinity DataIC50: >1.00E+5nMpH: 7.4 T: 2°CAssay Description:The reaction mixture (1 mL, pH 7.4) contained 100mM triethanolamine, 10mM EDTA, 0.2mM NADH, 1mM glyceraldehyde 3-phosphate (GAP) and 0.9 units of a-g...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTriosephosphate isomerase, glycosomal(Trypanosoma cruzi)
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50534547(CHEMBL4443832)
Affinity DataIC50:  2.23E+5nMAssay Description:Inhibition of recombinant Trypanosoma cruzi triosephosphate isomerase assessed as reduction of DHAP after 2 hrs by measuring NADH consumption by alph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTriosephosphate isomerase(Oryctolagus cuniculus)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50167773(CHEMBL196558 | [2-(N-Hydroxycarbamimidoyl)-ethyl]-...)
Affinity DataIC50:  9.60E+6nMAssay Description:Inhibitory concentration against rabbit muscle triose-phosphate isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTriosephosphate isomerase(Oryctolagus cuniculus)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50167774((2-Hydrazinocarbonyl-ethyl)-phosphonic acid | CHEM...)
Affinity DataIC50:  2.70E+7nMAssay Description:Inhibitory concentration against rabbit muscle triose-phosphate isomeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed