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Found 96 Enz. Inhib. hit(s) with Target = 'Uridine phosphorylase 1'
TargetUridine phosphorylase 1(Homo sapiens (Human))
Instituto De ParasitologíA Y Biomedicina LóPez-Neyra

Curated by ChEMBL
LigandPNGBDBM50330391(5-(3-(benzyloxy)benzyl)-1-((2-hydroxyethoxy)methyl...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of human uridine phosphorylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Homo sapiens (Human))
Instituto De ParasitologíA Y Biomedicina LóPez-Neyra

Curated by ChEMBL
LigandPNGBDBM50078082(5-(3-Benzyloxy-benzyl)-pyrimidine-2,4,6-trione | C...)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of human uridine phosphorylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50030972(5-(3-sec-Butoxy-benzyl)-1-(2-hydroxy-ethoxymethyl)...)
Affinity DataIC50:  27nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50031005(1-(2-Hydroxy-ethoxymethyl)-5-(3-propoxy-benzyl)-1H...)
Affinity DataIC50:  47nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50030974(1-(2-Hydroxy-1-hydroxymethyl-ethoxymethyl)-5-(3-pr...)
Affinity DataIC50:  60nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50031009(1-(2-Hydroxy-ethoxymethyl)-5-(3-isobutoxy-benzyl)-...)
Affinity DataIC50:  66nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50030990(5-[3-(3-Fluoro-propoxy)-benzyl]-1-(2-hydroxy-ethox...)
Affinity DataIC50:  68nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50030980(1-((2-HYDROXYETHOXY)METHYL)-5-(3-(BENZYLOXY)BENZYL...)
Affinity DataIC50:  84nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50031006(5-(3-Ethoxy-benzyl)-1-(2-hydroxy-ethoxymethyl)-1H-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50031007(5-[3-(3-Fluoro-propoxy)-benzyl]-1-(2-hydroxy-1-hyd...)
Affinity DataIC50:  110nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50030999(5-(3-Chloro-benzyl)-1-(2-hydroxy-1-hydroxymethyl-e...)
Affinity DataIC50:  110nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50030983(5-(3-Allyloxy-benzyl)-1-(2-hydroxy-ethoxymethyl)-1...)
Affinity DataIC50:  130nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50031004(1-(2-Hydroxy-ethoxymethyl)-5-(3-isopropoxy-benzyl)...)
Affinity DataIC50:  160nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50030995(5-(3-Butoxy-benzyl)-1-(2-hydroxy-ethoxymethyl)-1H-...)
Affinity DataIC50:  160nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50030984(5-(3-Chloro-benzyl)-1-(2-hydroxy-ethoxymethyl)-1H-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50030981(5-(3,5-Difluoro-benzyl)-1-(2-hydroxy-ethoxymethyl)...)
Affinity DataIC50:  350nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50026387(1-((2-HYDROXYETHOXY)METHYL)-5-BENZYLPYRIMIDINE-2,4...)
Affinity DataIC50:  460nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50030976(5-(3-Fluoro-benzyl)-1-(2-hydroxy-ethoxymethyl)-1H-...)
Affinity DataIC50:  550nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50031001(5-(3-Propoxy-benzyl)-1H-pyrimidine-2,4-dione | CHE...)
Affinity DataIC50:  840nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50030975(5-(2-Fluoro-benzyl)-1-(2-hydroxy-ethoxymethyl)-1H-...)
Affinity DataIC50:  870nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50031000(5-(3-sec-Butoxy-benzyl)-1H-pyrimidine-2,4-dione | ...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50031002(5-(3-Isobutoxy-benzyl)-1H-pyrimidine-2,4-dione | C...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50031012(5-[3-(3-Fluoro-propoxy)-benzyl]-1H-pyrimidine-2,4-...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50031010(1-(2-Hydroxy-ethoxymethyl)-5-(3-methoxy-benzyl)-1H...)
Affinity DataIC50:  1.86E+3nMAssay Description:The compound was tested for inhibition of uridine phosphorylase (UrdPase) from murine liver Value refers to activity for apparent Ki valueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50030992(5-(3-Isopropoxy-benzyl)-1H-pyrimidine-2,4-dione | ...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50030987(5-(3-Ethoxy-benzyl)-1H-pyrimidine-2,4-dione | CHEM...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50030989(5-(3-Chloro-benzyl)-1H-pyrimidine-2,4-dione | CHEM...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50030985(5-(3-Allyloxy-benzyl)-1H-pyrimidine-2,4-dione | CH...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50030997(5-(3-Methoxy-benzyl)-1H-pyrimidine-2,4-dione | CHE...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50031008(5-(2-Fluoro-benzyl)-1H-pyrimidine-2,4-dione | CHEM...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50030998(5-Benzyl-1H-pyrimidine-2,4-dione | CHEMBL275965)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50030982(5-(4-Nitro-benzyl)-1H-pyrimidine-2,4-dione | CHEMB...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50031013(5-(3-Fluoro-benzyl)-1H-pyrimidine-2,4-dione | CHEM...)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50030977(5-(4-Methyl-benzyl)-1H-pyrimidine-2,4-dione | CHEM...)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50030988(5-(3,5-Difluoro-benzyl)-1H-pyrimidine-2,4-dione | ...)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50030978(5-(2-Methoxy-benzyl)-1H-pyrimidine-2,4-dione | CHE...)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50030991(5-(3-Methyl-benzyl)-1H-pyrimidine-2,4-dione | CHEM...)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50031011(5-(3-Butoxy-benzyl)-1H-pyrimidine-2,4-dione | CHEM...)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50030993(5-[3-(4,4,4-Trifluoro-butoxy)-benzyl]-1H-pyrimidin...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50030973(5-(4-Chloro-benzyl)-1H-pyrimidine-2,4-dione | CHEM...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50031014(3-(2,4-Dioxo-1,2,3,4-tetrahydro-pyrimidin-5-ylmeth...)
Affinity DataIC50:  1.32E+4nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50030994(5-Benzo[1,3]dioxol-5-ylmethyl-1H-pyrimidine-2,4-di...)
Affinity DataIC50:  1.36E+4nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50030986(5-(3,4-Dichloro-benzyl)-1H-pyrimidine-2,4-dione | ...)
Affinity DataIC50:  1.55E+4nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50030996(5-(4-Fluoro-benzyl)-1H-pyrimidine-2,4-dione | CHEM...)
Affinity DataIC50:  1.64E+4nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50031003(4-(2,4-Dioxo-1,2,3,4-tetrahydro-pyrimidin-5-ylmeth...)
Affinity DataIC50:  2.11E+4nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50031015(5-(3-Trifluoromethyl-benzyl)-1H-pyrimidine-2,4-dio...)
Affinity DataIC50:  2.14E+4nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50031017(5-(2-Chloro-benzyl)-1H-pyrimidine-2,4-dione | CHEM...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50031016(5-(3,4-Difluoro-benzyl)-1H-pyrimidine-2,4-dione | ...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50030971(5-(2-Methyl-benzyl)-1H-pyrimidine-2,4-dione | CHEM...)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine phosphorylase 1(Mus musculus)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50030979(5-(4-Methoxy-benzyl)-1H-pyrimidine-2,4-dione | CHE...)
Affinity DataIC50:  6.65E+4nMAssay Description:Inhibition of uridine phosphorylase (UrdPase) from murine liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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