TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:In vitro displacement of [3H]-LY 278584 from rat cerebral cortex 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cellsMore data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Inhibition of endothelin-converting enzyme in human umbilical vein endothelial cellsMore data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibition of VKORC1 in rat liver microsomes in presence of 0.003 to 0.2 mM vitamin KMore data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Inhibition of neutral endopeptidase in human umbilical vein endothelial cellsMore data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Inhibition of VKORC1 in rat liver microsomes in presence of 0.003 to 0.2 mM vitamin KMore data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Inhibition of VKORC1 in rat liver microsomes in presence of 0.003 to 0.2 mM vitamin KMore data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 90nMAssay Description:Inhibition of VKORC1 in rat liver microsomes in presence of 0.003 to 0.2 mM vitamin KMore data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 90nMAssay Description:Inhibition of VKORC1 in rat liver microsomes in presence of 0.003 to 0.2 mM vitamin KMore data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Inhibition of Endothelin-converting enzyme of guinea pig lung membraneMore data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:In vitro displacement of [3H]-LY 278584 from rat cerebral cortex 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Inhibition of VKORC1 in rat liver microsomes in presence of 0.003 to 0.2 mM vitamin KMore data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 260nMAssay Description:In vitro displacement of [3H]-LY 278584 from rat cerebral cortex 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 600nM ΔG°: -36.9kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, standard reactions were performed in 200 mM Hepes buffer, pH 7.4, containing 150 mM KCl, 1 mM dithiothreitol, 0.25 to 2 g liter-1...More data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Homo sapiens (Human))
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School Of Lyon
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School Of Lyon
Affinity DataKi: 1.80E+3nM ΔG°: -34.1kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, standard reactions were performed in 200 mM Hepes buffer, pH 7.4, containing 150 mM KCl, 1 mM dithiothreitol, 0.25 to 2 g liter-1...More data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 3.90E+3nMAssay Description:In vitro displacement of [3H]-LY 278584 from rat cerebral cortex 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Bos taurus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataKi: 8.00E+3nMAssay Description:Apparent kinetic constant of the compound for Vitamin K epoxide reductaseMore data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Bos taurus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataKi: 1.60E+4nMAssay Description:Binding affinity of the compound for vitamin K epoxide reductaseMore data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Bos taurus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataKi: 1.70E+4nMAssay Description:Apparent kinetic constant of the compound for Vitamin K epoxide reductaseMore data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 2.20E+4nMAssay Description:Inhibition of neutral endopeptidase in human umbilical vein endothelial cellsMore data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Bos taurus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataKi: 2.60E+4nMAssay Description:Apparent kinetic constant of the compound for Vitamin K epoxide reductaseMore data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1-like protein 1(Rattus norvegicus (Rat))
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School Of Lyon
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School Of Lyon
Affinity DataKi: 3.26E+4nM ΔG°: -26.6kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, standard reactions were performed in 200 mM Hepes buffer, pH 7.4, containing 150 mM KCl, 1 mM dithiothreitol, 0.25 to 2 g liter-1...More data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Bos taurus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataKi: 4.30E+4nMAssay Description:Apparent kinetic constant of the compound for Vitamin K epoxide reductaseMore data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Homo sapiens (Human))
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School Of Lyon
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School Of Lyon
Affinity DataKi: 4.48E+4nMAssay Description:Inhibition of VKORC1More data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1-like protein 1(Homo sapiens (Human))
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School Of Lyon
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School Of Lyon
Affinity DataKi: 5.20E+4nM ΔG°: -25.4kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, standard reactions were performed in 200 mM Hepes buffer, pH 7.4, containing 150 mM KCl, 1 mM dithiothreitol, 0.25 to 2 g liter-1...More data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Bos taurus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataKi: 6.30E+4nMAssay Description:Apparent kinetic constant of the compound for Vitamin K epoxide reductaseMore data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Bos taurus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataKi: 6.30E+4nMAssay Description:Apparent kinetic constant of the compound for Vitamin K epoxide reductaseMore data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Homo sapiens (Human))
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School Of Lyon
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School Of Lyon
Affinity DataKi: 6.89E+4nMAssay Description:Inhibition of VKORC1More data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Bos taurus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataKi: 7.40E+4nMAssay Description:Apparent kinetic constant of the compound for Vitamin K epoxide reductaseMore data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Homo sapiens (Human))
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School Of Lyon
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School Of Lyon
Affinity DataKi: 7.42E+4nMAssay Description:Inhibition of VKORC1More data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Homo sapiens (Human))
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School Of Lyon
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School Of Lyon
Affinity DataKi: 7.96E+4nMAssay Description:Inhibition of VKORC1More data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Bos taurus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataKi: 1.00E+5nMAssay Description:Apparent kinetic constant of the compound for Vitamin K epoxide reductaseMore data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Homo sapiens (Human))
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School Of Lyon
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School Of Lyon
Affinity DataIC50: 4.5nMAssay Description:Inhibition of VKOR (unknown origin) in HEK293 expressing FIXgla-PC incubated for 48 hrs by ELISAMore data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Homo sapiens (Human))
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School Of Lyon
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School Of Lyon
Affinity DataIC50: 8.80nMAssay Description:Inhibition of VKOR (unknown origin) in HEK293 expressing FIXgla-PC incubated for 48 hrs by ELISAMore data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Bos taurus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibitory concentration against beef liver Vitamin K epoxide reductase (vitamin K 2,3-epoxide reductase)More data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Homo sapiens (Human))
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School Of Lyon
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School Of Lyon
Affinity DataIC50: 58nMAssay Description:Inhibition of VKOR (unknown origin) in HEK293 expressing FIXgla-PC incubated for 48 hrs by ELISAMore data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Homo sapiens (Human))
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School Of Lyon
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School Of Lyon
Affinity DataIC50: 59nMAssay Description:Inhibition of VKOR (unknown origin) in HEK293 expressing FIXgla-PC incubated for 48 hrs by ELISAMore data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Homo sapiens (Human))
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School Of Lyon
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School Of Lyon
Affinity DataIC50: 90nMAssay Description:Inhibition of VKOR (unknown origin) in HEK293 expressing FIXgla-PC incubated for 48 hrs by ELISAMore data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Bos taurus)
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against beef liver Vitamin K epoxide reductase (vitamin K 2,3-epoxide reductase)More data for this Ligand-Target Pair
TargetVitamin K epoxide reductase complex subunit 1(Homo sapiens (Human))
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School Of Lyon
Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School Of Lyon
Affinity DataIC50: 1.93E+3nMAssay Description:Inhibition of VKOR (unknown origin) in HEK293 expressing FIXgla-PC incubated for 48 hrs by ELISAMore data for this Ligand-Target Pair