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Found 3 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PAK 1 [249-545,K299R]'
TargetSerine/threonine-protein kinase PAK 1 [249-545,K299R](Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50112347(CHEMBL3609327 | FRAX597)
Affinity DataIC50:  7.70nMAssay Description:IC50 values were determined using a 10 concentration point, non-radioactive, functional assay that employs a fluorescence-based, coupled enzyme forma...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 1 [249-545,K299R](Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM213235(FRAX414)
Affinity DataIC50:  20nMAssay Description:IC50 values were determined using a 10 concentration point, non-radioactive, functional assay that employs a fluorescence-based, coupled enzyme forma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 1 [249-545,K299R](Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM6276(8-Cyclopentyl-2-[4-(4-methylpiperazin-1-yl)phenyla...)
Affinity DataIC50:  483nMAssay Description:IC50 values were determined using a 10 concentration point, non-radioactive, functional assay that employs a fluorescence-based, coupled enzyme forma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed