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Found 12 Enz. Inhib. hit(s) with Target = 'Glutamine--tRNA ligase'
TargetGlutamine--tRNA ligase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50366674(CHEMBL609187)
Affinity DataKi:  280nMAssay Description:The compound was evaluated for inhibition of Glutaminyl-tRNA synthetase with respect to glutamine.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamine--tRNA ligase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50366674(CHEMBL609187)
Affinity DataKi:  860nMAssay Description:The compound was evaluated for inhibition of Glutaminyl-tRNA synthetase for Escherichia coli with respect to ATP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamine--tRNA ligase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50366675(CHEMBL609496)
Affinity DataKi:  1.30E+3nMAssay Description:The compound was evaluated for binding affinity to Glutaminyl-tRNA synthetase with respect to glutamine.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamine--tRNA ligase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50366673(CHEMBL608302)
Affinity DataKi:  3.00E+3nMAssay Description:The compound was evaluated for inhibition of Glutaminyl-tRNA synthetase with respect to glutamine.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamine--tRNA ligase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50290175(4-ammonio-5-{[(2R,4S,6S)-4-hydroxy-6-(hydroxymethy...)
Affinity DataKi:  2.00E+4nMAssay Description:Compound was tested for the inhibition of Escherichia coli glutamyl-t-RNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamine--tRNA ligase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50290174(4-ammonio-5-{[(2R,6S)-6-(hydroxymethyl)piperidin-2...)
Affinity DataKi:  2.30E+5nMAssay Description:Compound was tested for the inhibition of Escherichia coli glutamyl-t-RNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamine--tRNA ligase(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50403640(CHEMBL2115178)
Affinity DataKi:  3.80E+5nMAssay Description:Compound was tested for the inhibition of Escherichia coli glutamyl-t-RNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamine--tRNA ligase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50366478(CHEMBL609498)
Affinity DataKi:  5.00E+5nMAssay Description:Compound was tested for the inhibition of Escherichia coli glutamyl-t-RNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamine--tRNA ligase(Escherichia coli)
Crefsip

LigandPNGBDBM18120(Gln-KPA | [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)...)
Affinity DataKi:  6.50E+5nM ΔG°:  -18.9kJ/molepH: 7.2 T: 2°CAssay Description:The Km and Kappm for the amino acid substrate were first calculated from Lineweaver-Burk plots. The Ki values were calculated from the Kappm vs [I] p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamine--tRNA ligase(Bos taurus (bovine))
Crefsip

LigandPNGBDBM18118((4S)-4-amino-6-({[(2R,3S,4R,5R)-5-(6-amino-9H-puri...)
Affinity DataKi:  2.60E+6nM ΔG°:  -15.3kJ/molepH: 7.2 T: 2°CAssay Description:The Km and Kappm for the amino acid substrate were first calculated from Lineweaver-Burk plots. The Ki values were calculated from the Kappm vs [I] p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamine--tRNA ligase(Escherichia coli)
Crefsip

LigandPNGBDBM18118((4S)-4-amino-6-({[(2R,3S,4R,5R)-5-(6-amino-9H-puri...)
Affinity DataKi:  2.80E+6nM ΔG°:  -15.2kJ/molepH: 7.2 T: 2°CAssay Description:The Km and Kappm for the amino acid substrate were first calculated from Lineweaver-Burk plots. The Ki values were calculated from the Kappm vs [I] p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamine--tRNA ligase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50403639(CHEMBL2114154)
Affinity DataKi:  1.14E+7nMAssay Description:Compound was tested for the inhibition of Escherichia coli glutamyl-t-RNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article