Found 78 Enz. Inhib. hit(s) with Target = 'DNA-directed RNA polymerase I subunit RPA1' TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 470nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 590nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 640nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 650nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 660nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 730nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 740nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 780nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 780nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 920nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 980nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 990nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.09E+3nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.25E+3nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.35E+3nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 2.01E+3nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 2.17E+3nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 3.04E+3nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 3.94E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 5.21E+3nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 5.75E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 6.86E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
