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Found 3 Enz. Inhib. hit(s) with Target = 'Acetyl-CoA acetyltransferase, mitochondrial'
TargetAcetyl-CoA acetyltransferase, mitochondrial(Homo sapiens)
Dr.Vishwanath Karad Mit World Peace University

Curated by ChEMBL
LigandPNGBDBM50599921(CHEMBL5203276)
Affinity DataIC50:  45nMAssay Description:Inhibition of human ACAT1 in HepG2 cells assessed as inhibition of triglyceride synthesis incubated for 1 hrs followed by 13C-addition of 13C-oleic a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetyl-CoA acetyltransferase, mitochondrial(Homo sapiens)
Dr.Vishwanath Karad Mit World Peace University

Curated by ChEMBL
LigandPNGBDBM50599923(CHEMBL5204128)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human ACAT1 in HepG2 cells assessed as inhibition of triglyceride synthesis incubated for 1 hrs followed by 13C-addition of 13C-oleic a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetyl-CoA acetyltransferase, mitochondrial(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50346601(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)
Affinity DataIC50:  7.79E+4nMAssay Description:Inhibition of rat liver microsomal ACATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed