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Found 1037 Enz. Inhib. hit(s) with Target = 'Arginase'
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50350311(CHEMBL1812661)
Affinity DataKi:  8.5nMAssay Description:Binding affinity to human arginase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50350311(CHEMBL1812661)
Affinity DataKi:  8.5nMAssay Description:Inhibition of human Arg2 at pH 7.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-1(Homo sapiens (Human))
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50561045(CHEMBL4758805)
Affinity DataKi: <10nMAssay Description:Inhibition of human Arg1 using L-arginine as substrate after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-1(Homo sapiens (Human))
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50561046(CHEMBL4790798)
Affinity DataKi: <10nMAssay Description:Inhibition of human Arg1 using L-arginine as substrate after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50561045(CHEMBL4758805)
Affinity DataKi: <10nMAssay Description:Inhibition of human Arg2 using L-arginine as substrate after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50561046(CHEMBL4790798)
Affinity DataKi: <10nMAssay Description:Inhibition of human Arg2 using L-arginine as substrate after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50561034(CHEMBL4244287)
Affinity DataKi:  30nMAssay Description:Inhibition of human Arg2 at pH 7.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50008099(CHEMBL1234777)
Affinity DataKi:  51nMAssay Description:Inhibition of arginase 2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50008099(CHEMBL1234777)
Affinity DataKi:  51nMAssay Description:Inhibition of human Arg2 at pH 7.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase(Leishmania amazonensis)
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM23417(α-CA inhibitor, 4 | (-)-Epicatechin | (2R,3R)...)
Affinity DataKi:  200nMAssay Description:Noncompetitive inhibition of Leishmania amazonensis recombinant arginase expressed in Escherichia coli Rosetta (DE3) pLysS using L-arginine as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase(Leishmania amazonensis)
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM23416(α-CA inhibitor, 3 | (+)-Catechin | (2R,3S)-2-...)
Affinity DataKi:  600nMAssay Description:Noncompetitive inhibition of Leishmania amazonensis recombinant arginase expressed in Escherichia coli Rosetta (DE3) pLysS using L-arginine as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase(Leishmania amazonensis)
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50241867(((2R,3R,4R,5R,6R)-6-(3,4-dihydroxyphenethoxy)-5-hy...)
Affinity DataKi:  700nMAssay Description:Competitive inhibition of Leishmania amazonensis arginase assessed as inhibition constant for enzyme-inhibitor complex using L-arginine as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase(Leishmania amazonensis)
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50446567(CHEMBL3109443)
Affinity DataKi:  900nMAssay Description:Noncompetitive inhibition of Leishmania amazonensis recombinant arginase expressed in Escherichia coli Rosetta (DE3) pLysS using L-arginine as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase(Leishmania amazonensis)
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM15236(3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chr...)
Affinity DataKi:  1.20E+3nMAssay Description:Noncompetitive inhibition of Leishmania amazonensis recombinant arginase expressed in Escherichia coli Rosetta (DE3) pLysS using L-arginine as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase(Leishmania amazonensis)
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50521944(CHEMBL4204512)
Affinity DataKi:  1.30E+3nMAssay Description:Competitive inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli assessed as reduction in urea production by measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50230418(CHEMBL260629 | N(gamma)-hydroxy-L-arginine | N-OME...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of human Arg2 at pH 7.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase(Schistosoma mansoni (flatworms))
University Of Pennsylvania

LigandPNGBDBM130378(2(S)-amino-6-boronohexanoic acid (ABH))
Affinity DataKi:  1.80E+3nMpH: 8.5Assay Description:Briefly, 0.5-50 mM L-arginine (pH 8.5) was added to a solution of 50 mM 4-(2-hydroxyethyl)piperazine-1-propanesulfonic acid (EPPS) (pH 8.5) and 100 &...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase(Schistosoma mansoni (flatworms))
University Of Pennsylvania

LigandPNGBDBM130379(N-hydroxy-L-arginine (NOHA))
Affinity DataKi:  3.70E+3nMpH: 8.5Assay Description:Briefly, 0.5-50 mM L-arginine (pH 8.5) was added to a solution of 50 mM 4-(2-hydroxyethyl)piperazine-1-propanesulfonic acid (EPPS) (pH 8.5) and 100 &...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase(Leishmania amazonensis)
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50446568(CHEMBL3109439)
Affinity DataKi:  3.80E+3nMAssay Description:Noncompetitive inhibition of Leishmania amazonensis recombinant arginase expressed in Escherichia coli Rosetta (DE3) pLysS using L-arginine as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-1(Homo sapiens (Human))
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50316603(2-(S)-amino-5-(2-aminoimidazol-1-yl)pentanoic acid...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of human recombinant full length arginase 1 expressed in Escherichia coli BL21(DE3) by fixed point assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase(Leishmania amazonensis)
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50521942(CHEMBL4216180)
Affinity DataKi:  5.10E+3nMAssay Description:Competitive inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli assessed as reduction in urea production by measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase(Leishmania amazonensis)
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM84978(Quercitrin | cid_5280459)
Affinity DataKi:  7.90E+3nMAssay Description:Noncompetitive inhibition of Leishmania amazonensis recombinant arginase expressed in Escherichia coli Rosetta (DE3) pLysS using L-arginine as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase(Plasmodium falciparum)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50350311(CHEMBL1812661)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of Plasmodium falciparum arginase using L-arginine as substrate by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase(Leishmania amazonensis)
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50510706(CHEMBL4515068)
Affinity DataKi:  1.70E+4nMAssay Description:Non-competitive inhibition of Leishmania amazonensis arginase using L-arginine as substrate incubated for 15 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-1(Bos taurus)
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50375814(CHEMBL260628)
Affinity DataKi:  1.71E+4nMAssay Description:Inhibition of bovine liver arginaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase(Leishmania amazonensis)
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50521943(CHEMBL4574177)
Affinity DataKi:  2.60E+4nMAssay Description:Competitive inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli assessed as reduction in urea production by measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-1(Bos taurus)
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50230418(CHEMBL260629 | N(gamma)-hydroxy-L-arginine | N-OME...)
Affinity DataKi:  3.00E+4nMAssay Description:Inhibition of bovine liver arginaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetArginase(Leishmania amazonensis)
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50521947(CHEMBL4530523)
Affinity DataKi:  3.20E+4nMAssay Description:Competitive inhibition of recombinant Leishmania amazonensis arginase expressed in Escherichia coli assessed as reduction in urea production by measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-1(Bos taurus)
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50553165(CHEMBL4754674)
Affinity DataKi:  8.20E+4nMAssay Description:Mixed type inhibition of recombinant bovine liver ARGI using L-arginine as substrate incubated for 60 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-1(Bos taurus)
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50553165(CHEMBL4754674)
Affinity DataKi:  8.20E+4nMAssay Description:Mixed type inhibition of recombinant bovine liver ARGI using L-arginine as substrate incubated for 60 mins by Cornish-Bowden plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-1(Bos taurus)
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50553165(CHEMBL4754674)
Affinity DataKi:  8.20E+4nMAssay Description:Mixed type inhibition of recombinant bovine liver ARGI using L-arginine as substrate incubated for 60 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-1(Bos taurus)
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50045936((E)-4-(3,5-dihydroxystyryl)benzene-1,2-diol | (E)-...)
Affinity DataKi:  1.36E+5nMAssay Description:Mixed type inhibition of recombinant bovine liver ARGI using L-arginine as substrate incubated for 60 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-1(Bos taurus)
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50045936((E)-4-(3,5-dihydroxystyryl)benzene-1,2-diol | (E)-...)
Affinity DataKi:  1.36E+5nMAssay Description:Mixed type inhibition of recombinant bovine liver ARGI using L-arginine as substrate incubated for 60 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-1(Bos taurus)
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50045936((E)-4-(3,5-dihydroxystyryl)benzene-1,2-diol | (E)-...)
Affinity DataKi:  1.36E+5nMAssay Description:Mixed type inhibition of recombinant bovine liver ARGI using L-arginine as substrate incubated for 60 mins by Cornish-Bowden plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase(Plasmodium falciparum)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50350309(CHEMBL1812662)
Affinity DataKi:  2.60E+5nMAssay Description:Inhibition of Plasmodium falciparum arginase using L-arginine as substrate by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-1(Homo sapiens (Human))
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50462601(CHEMBL4250607)
Affinity DataKi:  2.75E+5nMAssay Description:Irreversible inhibition of human arginase 1 using thioarginine as substrate measured up to 360 mins by UV micro plate methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-1(Homo sapiens (Human))
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50316607(2-amino-L-histidine | CHEMBL1099167 | L-2-aminohis...)
Affinity DataKi:  3.00E+5nMAssay Description:Inhibition of human recombinant full length arginase 1 expressed in Escherichia coli BL21(DE3) by fixed point assayMore data for this Ligand-Target Pair
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50462601(CHEMBL4250607)
Affinity DataKi:  3.22E+5nMAssay Description:Irreversible inhibition of human arginase 2 using thioarginine as substrate measured up to 360 mins by UV micro plate methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-1(Homo sapiens (Human))
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50462600(CHEMBL4238387)
Affinity DataKi:  3.82E+5nMAssay Description:Irreversible inhibition of human arginase 1 using thioarginine as substrate measured up to 360 mins by UV micro plate methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50462600(CHEMBL4238387)
Affinity DataKi:  4.37E+5nMAssay Description:Irreversible inhibition of human arginase 2 using thioarginine as substrate measured up to 360 mins by UV micro plate methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-1(Homo sapiens (Human))
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50316604((S)-2-amino-5-(imidazol-2-ylamino)pentanoic acid |...)
Affinity DataKi:  5.00E+5nMAssay Description:Inhibition of human recombinant full length arginase 1 expressed in Escherichia coli BL21(DE3) by fixed point assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase(Plasmodium falciparum)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50350310(CHEMBL1812663)
Affinity DataKi:  2.00E+6nMAssay Description:Inhibition of Plasmodium falciparum arginase using L-arginine as substrate by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-1(Homo sapiens (Human))
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50316606((2S)-2-amino-4-(2-amino-1H-imidazol-5-yl)butanoic ...)
Affinity DataKi:  3.00E+6nMAssay Description:Inhibition of human recombinant full length arginase 1 expressed in Escherichia coli BL21(DE3) by fixed point assayMore data for this Ligand-Target Pair
TargetArginase-1(Homo sapiens (Human))
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50316608(1H-Imidazol-2-yl-ammonium | 1H-Imidazol-2-ylamine ...)
Affinity DataKi:  3.60E+6nMAssay Description:Inhibition of human recombinant full length arginase 1 expressed in Escherichia coli BL21(DE3) by fixed point assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetArginase-1(Homo sapiens (Human))
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50316605(2-amino-5-(2-aminoimidazol-4-yl)pentanoic acid | C...)
Affinity DataKi: >8.00E+7nMAssay Description:Inhibition of human recombinant full length arginase 1 expressed in Escherichia coli BL21(DE3) by fixed point assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-1(Homo sapiens (Human))
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50561047(CHEMBL4764455)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of human Arg1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50561047(CHEMBL4764455)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of human Arg2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-1(Homo sapiens (Human))
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50561040(CHEMBL4754637)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human Arg1 by TOGA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-1(Homo sapiens (Human))
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50561042(CHEMBL4748950)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human Arg1 by TOGA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArginase-1(Homo sapiens (Human))
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50595729(CHEMBL5176739)
Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant human ARG1 expressed in Escherichia coli using L-arginine hydrochloride as substrate incubated for 1 hr by colorimetric ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
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