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Found 464 Enz. Inhib. hit(s) with Target = 'Dual specificity tyrosine-phosphorylation-regulated kinase 2'
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM350085(3-[3-[4-[dideuterio(methylamino)methyl]phenyl]isox...)
Affinity DataKi:  26nMAssay Description:ATP competitive inhibition of human DYRK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50463483(CHEMBL4245242)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of DYRK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50463479(CHEMBL4249925)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of DYRK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50583748(CHEMBL5084504)
Affinity DataIC50:  1nMAssay Description:Inhibition of DYRK2 (unknown origin) using Ulight-MBP as substrate and ATP as co-substrate incubated for 40 mins and measured after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM293424(US10106527, Compound 10 | US10106527, Compound 142...)
Affinity DataIC50:  2nMAssay Description:Inhibition of DYRK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50581236(CHEMBL5090676)
Affinity DataIC50:  2nMAssay Description:Inhibition of DYRK2 (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50530430(CHEMBL4460561)
Affinity DataIC50:  3nMAssay Description:Inhibition of DYRK2 (unknown origin) using Ulight-MBP as substrate and ATP as co-substrate incubated for 40 mins and measured after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of DYRK2 (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50583754(CHEMBL5077927)
Affinity DataIC50:  4nMAssay Description:Inhibition of DYRK2 (unknown origin) using Ulight-MBP as substrate and ATP as co-substrate incubated for 40 mins and measured after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50583749(CHEMBL5089294)
Affinity DataIC50:  5nMAssay Description:Inhibition of DYRK2 (unknown origin) using Ulight-MBP as substrate and ATP as co-substrate incubated for 40 mins and measured after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50583755(CHEMBL5070553)
Affinity DataIC50:  6nMAssay Description:Inhibition of DYRK2 (unknown origin) using Ulight-MBP as substrate and ATP as co-substrate incubated for 40 mins and measured after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50583747(CHEMBL5094409)
Affinity DataIC50:  6nMAssay Description:Inhibition of DYRK2 (unknown origin) using Ulight-MBP as substrate and ATP as co-substrate incubated for 40 mins and measured after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50583752(CHEMBL5073976)
Affinity DataIC50:  6nMAssay Description:Inhibition of DYRK2 (unknown origin) using Ulight-MBP as substrate and ATP as co-substrate incubated for 40 mins and measured after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50581233(CHEMBL5091510)
Affinity DataIC50:  8nMAssay Description:Inhibition of DYRK2 (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50594797(CHEMBL5195216)
Affinity DataIC50:  8nMAssay Description:Inhibition of GST-fused human recombinant DYRK2 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50583750(CHEMBL5072926)
Affinity DataIC50:  9nMAssay Description:Inhibition of DYRK2 (unknown origin) using Ulight-MBP as substrate and ATP as co-substrate incubated for 40 mins and measured after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50583753(CHEMBL5088511)
Affinity DataIC50:  9nMAssay Description:Inhibition of DYRK2 (unknown origin) using Ulight-MBP as substrate and ATP as co-substrate incubated for 40 mins and measured after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM621035((6-((4-(2-(dimethylamino)benzothiazole-6-yl)-5-flu...)
Affinity DataIC50:  9nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50583756(CHEMBL5080497)
Affinity DataIC50:  10nMAssay Description:Inhibition of DYRK2 (unknown origin) using Ulight-MBP as substrate and ATP as co-substrate incubated for 40 mins and measured after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50594785(CHEMBL5181008)
Affinity DataIC50:  11nMAssay Description:Inhibition of GST-fused human recombinant DYRK2 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50434353(CHEMBL2386747 | US9446044, 72)
Affinity DataIC50:  11nMAssay Description:Inhibition of DYRK2 (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50434353(CHEMBL2386747 | US9446044, 72)
Affinity DataIC50:  11nMAssay Description:Inhibition of DYRK2 (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50347746(CHEMBL1803085)
Affinity DataIC50:  11nMAssay Description:Inhibition of GST-fused human recombinant DYRK2 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presen...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50347750(CHEMBL1802358)
Affinity DataIC50:  14nMAssay Description:Inhibition of GST-fused human recombinant DYRK2 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presen...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM621015((6-((4-(2-(diethylamino)benzothiazole-6-yl)-5-fluo...)
Affinity DataIC50:  14nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50581240(CHEMBL5083159)
Affinity DataIC50:  14nMAssay Description:Inhibition of DYRK2 (unknown origin) by ADP hunter plus assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50581239(CHEMBL5082044)
Affinity DataIC50:  14nMAssay Description:Inhibition of DYRK2 (unknown origin) by ADP hunter plus assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50594790(CHEMBL5200518)
Affinity DataIC50:  15nMAssay Description:Inhibition of GST-fused human recombinant DYRK2 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM621042((6-((4-(2-(diethylamino)benzothiazole-6-yl)-5-fluo...)
Affinity DataIC50:  15nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM621006((6-((4-(2-(dimethylamino)benzothiazole-6-yl)-5-flu...)
Affinity DataIC50:  16nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50097868(CHEMBL3589661)
Affinity DataIC50:  16nMAssay Description:Inhibition of human recombinant DYRK2 expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50581212(CHEMBL5073598)
Affinity DataIC50:  20nMAssay Description:Inhibition of DYRK2 (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50581213(CHEMBL5088687)
Affinity DataIC50:  20nMAssay Description:Inhibition of DYRK2 (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50583757(CHEMBL5073869)
Affinity DataIC50:  21nMAssay Description:Inhibition of DYRK2 (unknown origin) using Ulight-MBP as substrate and ATP as co-substrate incubated for 40 mins and measured after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50583758(CHEMBL5071425)
Affinity DataIC50:  22nMAssay Description:Inhibition of DYRK2 (unknown origin) using Ulight-MBP as substrate and ATP as co-substrate incubated for 40 mins and measured after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50594788(CHEMBL5179457)
Affinity DataIC50:  22nMAssay Description:Inhibition of GST-fused human recombinant DYRK2 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50594784(CHEMBL5196066)
Affinity DataIC50:  23nMAssay Description:Inhibition of GST-fused human recombinant DYRK2 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50097855(CHEMBL3589666)
Affinity DataIC50:  23nMAssay Description:Inhibition of human recombinant DYRK2 expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM621046((6-((5-fluoro-4-(2-methylbenzothiazole-6-yl)pyrimi...)
Affinity DataIC50:  27nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50581213(CHEMBL5088687)
Affinity DataIC50:  30nMAssay Description:Inhibition of DYRK2 (unknown origin) by ADP hunter plus assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50594771(CHEMBL5181355)
Affinity DataIC50:  32nMAssay Description:Inhibition of GST-fused human recombinant DYRK2 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50594775(CHEMBL5203292)
Affinity DataIC50:  32nMAssay Description:Inhibition of GST-fused human recombinant DYRK2 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50097854(CHEMBL3589665)
Affinity DataIC50:  33nMAssay Description:Inhibition of human recombinant DYRK2 expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50594768(CHEMBL5195122)
Affinity DataIC50:  33nMAssay Description:Inhibition of GST-fused human recombinant DYRK2 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50594782(CHEMBL5206744)
Affinity DataIC50:  33nMAssay Description:Inhibition of GST-fused human recombinant DYRK2 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50583763(CHEMBL5093661)
Affinity DataIC50:  33nMAssay Description:Inhibition of DYRK2 (unknown origin) using Ulight-MBP as substrate and ATP as co-substrate incubated for 40 mins and measured after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50347745(CHEMBL1803084)
Affinity DataIC50:  34nMAssay Description:Inhibition of GST-fused human recombinant DYRK2 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presen...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50583759(CHEMBL5077422)
Affinity DataIC50:  34nMAssay Description:Inhibition of DYRK2 (unknown origin) using Ulight-MBP as substrate and ATP as co-substrate incubated for 40 mins and measured after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM620995((6-((4-(benzothiazole-6-yl)-5-fluoropyrimidine-2-y...)
Affinity DataIC50:  35nMAssay Description:The DYRK2 kinase inhibitory activity of the compounds of the invention were measured. The method was briefly described as follows (for specific metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe)

Curated by ChEMBL
LigandPNGBDBM50594783(CHEMBL5180765)
Affinity DataIC50:  35nMAssay Description:Inhibition of GST-fused human recombinant DYRK2 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
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