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Found 213 Enz. Inhib. hit(s) with Target = 'Dynamin-1'
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524304(Preparation of 4'-(4-methyl-1-((2-(piperidin-1-yl)...)
Affinity DataIC50:  720nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524237(Preparation of N-(4-(1H-tetrazol-5-yl)phenyl)-4-me...)
Affinity DataIC50:  910nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524268(Preparation of N-(4-(1H-pyrazol-4-yl)phenyl)-4-met...)
Affinity DataIC50:  1.20E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524266(Preparation of 4-methyl-1-((2-(piperidin-1-yl)thia...)
Affinity DataIC50:  1.20E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524269(Preparation of N-(4-(furan-3-yl)phenyl)-4-methyl-1...)
Affinity DataIC50:  1.20E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524267(Preparation of N-(4-(3,5-dimethylisoxazol-4-yl)phe...)
Affinity DataIC50:  1.40E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524253(Preparation of 4-methyl-N-(naphthalen-2-yl)-1-((2-...)
Affinity DataIC50:  1.60E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50177923(2-cyano-N-{3-[2-cyano-3-(3,4,5-trihydroxyphenyl)ac...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibitory activity against dynamin1 GTPase expressed in sheep brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50177937(2-cyano-N-{3-[2-cyano-3-(3,4,5-trihydroxyphenyl)ac...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibitory activity against dynamin1 GTPase expressed in sheep brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524246(US11168080, Compound A-16)
Affinity DataIC50:  1.70E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM5149((2E)-2-cyano-N-{3-[(2E)-2-cyano-3-(3,4-dihydroxyph...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibitory activity against dynamin1 GTPase expressed in sheep brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524256(Preparation of N-cyclohexyl-4-methyl-1-((2-(piperi...)
Affinity DataIC50:  1.70E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50177941(2-cyano-N-{3-[2-cyano-3-(3,4,5-trihydroxyphenyl)ac...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibitory activity against dynamin1 GTPase expressed in sheep brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524284(Preparation of Methyl 4-phenyl-1-((2-(piperidin-1-...)
Affinity DataIC50:  1.80E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524252(Preparation of 4-methyl-N-(4-(methylcarbamoyl)phen...)
Affinity DataIC50:  1.80E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524234(BDBM524245 | Preparation of Methyl 3-(4-methyl-1-(...)
Affinity DataIC50:  1.90E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524285(US11168080, Compound A-52)
Affinity DataIC50:  2.10E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM5152((2E)-2-cyano-N-{4-[(2E)-2-cyano-3-(3,4,5-trihydrox...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibitory activity against dynamin1 GTPase expressed in sheep brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524300(Preparation of N-(4-(1H-tetrazol-5-yl)phenyl)-4-me...)
Affinity DataIC50:  2.10E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524234(BDBM524245 | Preparation of Methyl 3-(4-methyl-1-(...)
Affinity DataIC50:  2.20E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524291(Preparation of N-(4-(1H-tetrazol-5-yl)phenyl)-4-ph...)
Affinity DataIC50:  2.20E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524303(Preparation of (2-bromothiazol-4-yl)methanol | US1...)
Affinity DataIC50:  2.30E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524238(Preparation of 4-methyl-1-((2-(piperidin-1-yl)thia...)
Affinity DataIC50:  2.50E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524294(Preparation of N-(4-iodo-3-methylphenyl)-4-methyl-...)
Affinity DataIC50:  2.50E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524249(Preparation of Ethyl (3-methylpiperidine-1-carbono...)
Affinity DataIC50:  2.70E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524290(Preparation of N-(3-fluoro-4-iodophenyl)-4-methyl-...)
Affinity DataIC50:  2.80E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524271(Preparation of N-(1H-indazol-5-yl)-4-methyl-1-((2-...)
Affinity DataIC50:  2.90E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50147563(CHEMBL109458 | Trimethyl-octadecyl-ammonium; bromi...)
Affinity DataIC50:  3.15E+3nMAssay Description:Concentration required against dynamin-1 GTPase activity of sheep brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524213(Preparation of Methyl 3-((4-methyl-1-((2-(piperidi...)
Affinity DataIC50:  3.20E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM5151((2E)-2-cyano-N-{4-[(2E)-2-cyano-3-(3,4-dihydroxyph...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibitory activity against dynamin1 GTPase expressed in sheep brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524296(Preparation of 4-bromo-1-((2-(piperidin-1-yl)thiaz...)
Affinity DataIC50:  3.40E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524248(Preparation of 2-(azepan-1-yl)-4-(chloromethyl)thi...)
Affinity DataIC50:  3.40E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50323462(3-hydroxy-N'-(3-hydroxy-4-methoxybenzylidene)-2-na...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of GTPase activity of Dynamin 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524247(US11168080, Compound A-17)
Affinity DataIC50:  3.80E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524250(Preparation of Ethyl 2-(2-methylpiperidin-1-yl)thi...)
Affinity DataIC50:  3.90E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524272(Preparation of 4-methyl-N-(2-oxoindolin-5-yl)-1-((...)
Affinity DataIC50:  4.20E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524275(Preparation of 4-methyl-N-(4-(2-oxoimidazolidin-1-...)
Affinity DataIC50:  4.30E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM58941(CHEMBL307346 | Hexadecyltrimethylammonium hydroxid...)
Affinity DataIC50:  4.37E+3nMAssay Description:Concentration required against dynamin-1 GTPase activity of sheep brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524263(Preparation of N-(4-iodophenyl)-4-methyl-1-((2-(pi...)
Affinity DataIC50:  4.50E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524213(Preparation of Methyl 3-((4-methyl-1-((2-(piperidi...)
Affinity DataIC50:  4.80E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM5153((2E)-2-cyano-N-{5-[(2E)-2-cyano-3-(3,4-dihydroxyph...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibitory activity against dynamin1 GTPase expressed in sheep brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50177943(2-cyano-N-{3-[2-cyano-3-(3,4-dihydroxy-5-methoxyph...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibitory activity against dynamin1 GTPase expressed in sheep brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50268295(2-Cyano-N-octyl-3-(1-(3-dimethylaminopropyl)-1H-in...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of dynamin 1-mediated endocytosis internalization of Tf-A594 in human U2OS cells pretreated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524236(Preparation of N-(4-(N-acetylsulfamoyl)phenyl)-4-m...)
Affinity DataIC50:  5.00E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50323461(CHEMBL1208862 | N'-(3,4-dihydroxybenzylidene)-2-na...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of GTPase activity of Dynamin 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM5150((2E)-2-cyano-N-{2-[(2E)-2-cyano-3-(3,4-dihydroxyph...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibitory activity against dynamin1 GTPase expressed in sheep brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50177940(2-cyano-N-{3-[2-cyano-3-(3,4-dihydroxyphenyl)acryl...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibitory activity against dynamin1 GTPase expressed in sheep brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524243(Preparation of Methyl trans-4-(4-methyl-1-((2-(pip...)
Affinity DataIC50:  5.50E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524282(Preparation of Methyl 4-(1-((2-(1H-pyrazol-4-yl)th...)
Affinity DataIC50:  5.60E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDynamin-1-like protein(Human)
Mitobridge

US Patent
LigandPNGBDBM524255(Preparation of N-cyclopentyl-4-methyl-1-((2-(piper...)
Affinity DataIC50:  5.70E+3nMAssay Description:The GTPase activity of Drp1 was assayed using a colorimetric assay similar to as described previously by Leonard M. et al. “Robust colorimetric assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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