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Found 414 Enz. Inhib. hit(s) with Target = '2-Hydroxyacid oxidase 1'
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50463046(CHEMBL1229989)
Affinity DataKi:  15nMAssay Description:Inhibition of human N-terminal His-tagged glycolate oxidase expressed in C41(D43) Escherichia coli using glycolate as substrate preincubated for 30 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50463046(CHEMBL1229989)
Affinity DataKi:  15nMAssay Description:Inhibition of human glycolate oxidase expressed in Escherichia coli using glycolate as substrate by DCIP dye based spectrophotometry analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50594014(CHEMBL5182027)
Affinity DataKi:  1.10E+3nMAssay Description:Non-competitive mixed inhibition of N-terminal His-tagged human recombinant glycolate oxidase expressed in Escherichia coli BL21 (DE3) cells assessed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50594018(CHEMBL5180187)
Affinity DataKi:  2.30E+3nMAssay Description:Non-competitive mixed inhibition of N-terminal His-tagged human recombinant glycolate oxidase expressed in Escherichia coli BL21 (DE3) cells assessed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target2-Hydroxyacid oxidase 1(Mus musculus)
Chinook Therapeutics

Curated by ChEMBL
LigandPNGBDBM50463047(CHEMBL1794748)
Affinity DataKi:  4.50E+3nMAssay Description:Non competitive inhibition of mouse glycolate oxidase in hyperoxaluric-Agxt knockdown mouse primary hepatocyte assessed as reduction in oxalate produ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-Hydroxyacid oxidase 1(Mus musculus)
Chinook Therapeutics

Curated by ChEMBL
LigandPNGBDBM50463040(CHEMBL4247590)
Affinity DataKi:  7.90E+3nMAssay Description:Non-competitive mixed inhibition of N-terminal His-tagged mouse recombinant glycolate oxidase expressed in Escherichia coli BL21 (DE3) cells assessed...More data for this Ligand-Target Pair
In DepthDetails PubMed
Target2-Hydroxyacid oxidase 1(Mus musculus)
Chinook Therapeutics

Curated by ChEMBL
LigandPNGBDBM50594017(CHEMBL5190607)
Affinity DataKi:  1.11E+4nMAssay Description:Non-competitive mixed inhibition of N-terminal His-tagged mouse recombinant glycolate oxidase expressed in Escherichia coli BL21 (DE3) cells assessed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50463040(CHEMBL4247590)
Affinity DataKi:  1.82E+4nMAssay Description:Non-competitive mixed inhibition of N-terminal His-tagged human recombinant glycolate oxidase expressed in Escherichia coli BL21 (DE3) cells assessed...More data for this Ligand-Target Pair
In DepthDetails PubMed
Target2-Hydroxyacid oxidase 1(Mus musculus)
Chinook Therapeutics

Curated by ChEMBL
LigandPNGBDBM50463047(CHEMBL1794748)
Affinity DataKi:  2.03E+4nMAssay Description:Inhibition of mouse N-terminal His-tagged glycolate oxidase expressed in BL21(DE3) Escherichia coli using glycolate as substrate by Cornish-Bowden pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50594017(CHEMBL5190607)
Affinity DataKi:  2.47E+4nMAssay Description:Non-competitive mixed inhibition of N-terminal His-tagged human recombinant glycolate oxidase expressed in Escherichia coli BL21 (DE3) cells assessed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target2-Hydroxyacid oxidase 1(Mus musculus)
Chinook Therapeutics

Curated by ChEMBL
LigandPNGBDBM50463040(CHEMBL4247590)
Affinity DataKi:  4.72E+4nMAssay Description:Inhibition of mouse recombinant glycolate oxidase expressed in Escherichia coli using glycolate as substrate by Dixon plot and Cornish-Bowden plot an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581194(5-(4-(2-(3-chlorophenyl) ethynyl)phenoxy)-1H-1,2,...)
Affinity DataIC50:  0.300nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581193(5-(4-(2-(4-chlorophenyl) ethynyl)phenoxy)-1H-1,2,...)
Affinity DataIC50:  0.400nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50572931(CHEMBL4855986)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of recombinant human GOX expressed in Escherichia coli C41 (DE3) using glycolate as substrate preincubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581140(5-(4-(()ethynyl)phenoxy)-1H- 1,2,3-triazole-4-car...)
Affinity DataIC50:  1nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581234(5-(3-(2-(1H-indazol-6- yl)ethynyl)phenoxy)-1H-1,2...)
Affinity DataIC50:  1nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581148(5-(3-((3- chlorophenyl)ethynyl)phenoxy)- 1H-1,2,...)
Affinity DataIC50:  1nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581155(5-(3-(2-(1-methyl-1H-pyrazol- 4-yl)ethynyl)phenox...)
Affinity DataIC50:  1nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581159(5-(3-((1-methyl-2-oxo-1,2- dihydropyridin-4- yl)...)
Affinity DataIC50:  1nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581161(5-(4-fluoro-3-(2- phenylethynyl)phenoxy)-1H- 1,2...)
Affinity DataIC50:  1nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581164(5-(4-methyl-3-(2- phenylethynyl)phenoxy)-1H- 1,2...)
Affinity DataIC50:  1nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581170(5-(3-((4- cyanophenyl)ethynyl)-4- fluorophenoxy)...)
Affinity DataIC50:  1nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581171(5-(4-((4- cyanophenyl)ethynyl)-3- fluorophenoxy)...)
Affinity DataIC50:  1nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581172(5-(4-((3- cyanophenyl)ethynyl)-3- fluorophenoxy)...)
Affinity DataIC50:  1nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581180(5-(4-(2-(3-fluorophenyl) ethynyl)phenoxy)-1H-1,2,...)
Affinity DataIC50:  1nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581143(5-(3-fluoro-4- (phenylethynyl)phenoxy)-1H- 1,2,3...)
Affinity DataIC50:  1nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581232(5-(3-(2-(1H-indazol-4- yl)ethynyl)phenoxy)-1H-1,2...)
Affinity DataIC50:  1nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581191(5-(4-(2-(4-fluorophenyl) ethynyl)phenoxy)-1H-1,2,...)
Affinity DataIC50:  1nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581192(5-(3-(2-(4-fluorophenyl) ethynyl)phenoxy)-1H-1,2,...)
Affinity DataIC50:  1nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581198(5-(3-(2-(6-methylpyridin-3- yl)ethynyl)phenoxy)-1...)
Affinity DataIC50:  1nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581199(5-(3-(2-(2-methylpyridin-4- yl)ethynyl)phenoxy)-1...)
Affinity DataIC50:  1nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581211(5-(3-(2-(1H-indazol-5- yl)ethynyl)phenoxy)-1H-1,2...)
Affinity DataIC50:  1nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50572933(CHEMBL4861379)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of recombinant human GOX expressed in Escherichia coli C41 (DE3) using glycolate as substrate preincubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50572932(CHEMBL4850573)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of recombinant human GOX expressed in Escherichia coli C41 (DE3) using glycolate as substrate preincubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581151(5-(4-((1-methyl-6-oxo-1,6- dihydropyridin-3- yl)...)
Affinity DataIC50:  2nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581246(5-(3-(2-(thiazol-2- yl)ethynyl)phenoxy)-1H-1,2,3-...)
Affinity DataIC50:  2nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581160(5-(3-fluoro-5-(2- phenylethynyl)phenoxy)-1H- 1,2...)
Affinity DataIC50:  2nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581165(5-(4-(trifluoromethyl)-3-(2- phenylethynyl)phenox...)
Affinity DataIC50:  2nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581168(5-(4-fluoro-3-(2-(4- (methylsulfonyl)phenyl)ethyn...)
Affinity DataIC50:  2nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581169(5-(4-fluoro-3-(2-(3- (methylsulfonyl)phenyl)ethyn...)
Affinity DataIC50:  2nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581173(5-(4-((3- cyanophenyl)ethynyl)-3- fluorophenoxy)...)
Affinity DataIC50:  2nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581174(5-(3-fluoro-4-(2-(4- (methylsulfonyl)phenyl)ethyn...)
Affinity DataIC50:  2nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581175(5-(3-fluoro-4-(2-(3- (methylsulfonyl)phenyl)ethyn...)
Affinity DataIC50:  2nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581179(4-(3-((3-cyanophenyl) ethynyl)-5-fluorophenoxy)- ...)
Affinity DataIC50:  2nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581181(5-(3-(2-(3-fluorophenyl) ethynyl)phenoxy)-1H-1,2,...)
Affinity DataIC50:  2nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581183(5-(4-(2-(3- methoxyphenyl)ethynyl)phenoxy)- 1H-1...)
Affinity DataIC50:  2nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM560934(5-(3- (benzo[d][1,3]dioxol- 5-yl)phenoxy)-1H- 1,2,...)
Affinity DataIC50:  2nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalent of hGOX. The enzy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581195(5-(3-(2-(4-chlorophenyl) ethynyl)phenoxy)-1H-1,2,...)
Affinity DataIC50:  2nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581219(5-(3-(2-(1-methyl-1H-indazol- 4-yl)ethynyl)phenox...)
Affinity DataIC50:  2nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM581220(5-(4-(2-(1-methyl-1H-indazol- 5-yl)ethynyl)phenox...)
Affinity DataIC50:  2nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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