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Found 37 Enz. Inhib. hit(s) with Target = 'Insulin-like growth factor-binding protein 5'
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106431(1-(3,4-Dihydroxy-benzoyl)-6,7-dihydroxy-isoquinoli...)
Affinity DataKi:  5.20nMAssay Description:The compound was tested for binding affinity against Insulin-like growth factor binding protein 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106431(1-(3,4-Dihydroxy-benzoyl)-6,7-dihydroxy-isoquinoli...)
Affinity DataKi:  5.60nMAssay Description:Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106443(1-(3,4-Dihydroxy-benzyl)-6,7-dihydroxy-isoquinolin...)
Affinity DataKi:  7.20nMAssay Description:Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128459(4-(3,4-Dihydroxy-benzyl)-6,7-dihydroxy-quinoline-2...)
Affinity DataKi:  13nMAssay Description:Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106432((3,4-Dihydroxy-phenyl)-(3,6,7-trihydroxy-isoquinol...)
Affinity DataKi:  21nMAssay Description:The compound was tested for binding affinity against Insulin-like growth factor binding protein 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128462(7-Amino-4-(3,4-dihydroxy-benzyl)-6-hydroxy-quinoli...)
Affinity DataKi:  52nMAssay Description:Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128461(4-(3,4-Dihydroxy-benzyl)-7-fluoro-6-hydroxy-quinol...)
Affinity DataKi:  53nMAssay Description:Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128458(4-(3,4-Dihydroxy-benzyl)-6-hydroxy-quinoline-2,7-d...)
Affinity DataKi:  110nMAssay Description:Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128456(7-Chloro-4-(3,4-dihydroxy-benzyl)-6-hydroxy-quinol...)
Affinity DataKi:  240nMAssay Description:Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128457(7-Amino-4-(3,4-dihydroxy-benzyl)-6-methoxy-quinoli...)
Affinity DataKi:  5.30E+3nMAssay Description:Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128460(4-(3,4-Dihydroxy-benzyl)-quinoline-2,6-dicarboxyli...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50121966(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Affinity DataKd:  2.36E+6nMAssay Description:Dissociation constant of the compound in PBS binding to Insulin-like growth factor binding protein 5 at the residue R87More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKd:  6.10E+8nMAssay Description:Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue L81More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50121966(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Affinity DataKd:  2.33E+6nMAssay Description:Dissociation constant of the compound in PBS binding to Insulin-like growth factor binding protein 5 at the residue S85More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50121966(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Affinity DataKd:  2.93E+6nMAssay Description:Dissociation constant of the compound in PBS binding to Insulin-like growth factor binding protein 5 at the residue L73More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50121966(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Affinity DataKd:  1.58E+6nMAssay Description:Dissociation constant of the compound in DMSO binding to Insulin-like growth factor binding protein 5 at the residue Y50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50121969(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-phenyl-p...)
Affinity DataKd:  1.08E+6nMAssay Description:Dissociation constant of the compound binding to Insulin-like growth factor binding protein 5 at the residue L-81More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50121966(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Affinity DataKd:  2.78E+6nMAssay Description:Dissociation constant of the compound in DMSO binding to Insulin-like growth factor binding protein 5 at the residue L81More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKd:  7.19E+8nMAssay Description:Dissociation constant of the compound in BS binding to Insulin-like growth factor binding protein 5 at the residue K91More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKd:  6.50E+8nMAssay Description:Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue S85More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50121966(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Affinity DataKd:  2.12E+6nMAssay Description:Dissociation constant of the compound in PBS binding to Insulin-like growth factor binding protein 5 at the residue K91More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKd:  5.41E+8nMAssay Description:Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue L73More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50121966(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Affinity DataKd:  1.72E+6nMAssay Description:Dissociation constant of the compound in PBS binding to Insulin-like growth factor binding protein 5 at the residue Y86More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKd:  6.48E+8nMAssay Description:Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue Y50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50121966(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Affinity DataKd:  2.88E+6nMAssay Description:Dissociation constant of the compound in PBS binding to Insulin-like growth factor binding protein 5 at the residue L81More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50121966(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Affinity DataKd:  1.31E+6nMAssay Description:Dissociation constant of the compound in DMSO binding to Insulin-like growth factor binding protein 5 at the residue L73More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50121966(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Affinity DataKd:  1.82E+6nMAssay Description:Dissociation constant of the compound in PBS binding to Insulin-like growth factor binding protein 5 at the residue Y50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50121966(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Affinity DataKd:  2.78E+6nMAssay Description:Dissociation constant of the compound binding to Insulin-like growth factor binding protein 5 at the residue L-81More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50121965(3-(4-tert-Butoxy-phenyl)-2-(9H-fluoren-9-ylmethoxy...)
Affinity DataKd:  7.18E+5nMAssay Description:Dissociation constant of the compound binding to Insulin-like growth factor binding protein 5 at the residue L-81More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50121968(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-4-methyl-p...)
Affinity DataKd:  1.09E+6nMAssay Description:Dissociation constant of the compound binding to Insulin-like growth factor binding protein 5 at the residue L-81More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKd:  7.83E+8nMAssay Description:Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue Y86More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50121966(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Affinity DataKd:  1.38E+6nMAssay Description:Dissociation constant of the compound in DMSO binding to Insulin-like growth factor binding protein 5 at the residue S85More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50121967(CHEMBL152301 | N-alpha-FMOC-L-tryptophan)
Affinity DataKd:  4.32E+4nMAssay Description:Dissociation constant of the compound binding to Insulin-like growth factor binding protein 5 at the residue L-81More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50121966(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Affinity DataKd:  2.42E+6nMAssay Description:Dissociation constant of the compound in DMSO binding to Insulin-like growth factor binding protein 5 at the residue K91More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKd:  9.21E+8nMAssay Description:Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue R87More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50121966(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Affinity DataKd:  1.90E+6nMAssay Description:Dissociation constant of the compound in DMSO binding to Insulin-like growth factor binding protein 5 at the residue Y86More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50121966(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Affinity DataKd:  1.64E+6nMAssay Description:Dissociation constant of the compound in DMSO binding to Insulin-like growth factor binding protein 5 at the residue R87More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed