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Found 44 Enz. Inhib. hit(s) with Target = 'Lactoperoxidase'
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM217355(4-benzyl-2-hydroxybenzenecarbohydroxamic acid (HX2...)
Affinity DataIC50:  40nMAssay Description:The halogenation activities of LPO (EC 1.11.1.7) and TPO (EC 1.11.1.8) were determined using a modified method of that described previously [Ferrari ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM50015089(2,N-Dihydroxy-benzamide | CHEMBL309339 | N,2-dihyd...)
Affinity DataIC50:  400nMAssay Description:The halogenation activities of LPO (EC 1.11.1.7) and TPO (EC 1.11.1.8) were determined using a modified method of that described previously [Ferrari ...More data for this Ligand-Target Pair
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM50238831(CHEMBL251689)
Affinity DataIC50:  800nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM81461(CAS_86-54-4 | Hydralazine | Hydralazine (HZN) | NS...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM217356(2-(benzylamino)-6-oxo-3H-pyrimidine-5-carbohydroxa...)
Affinity DataIC50:  2.00E+3nMAssay Description:The halogenation activities of LPO (EC 1.11.1.7) and TPO (EC 1.11.1.8) were determined using a modified method of that described previously [Ferrari ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM50238837(CHEMBL581893 | GNF-Pf-3346)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of cathepsin D.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM50238832(CHEMBL4080413)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM50238841(CHEMBL4098162)
Affinity DataIC50: >5.00E+3nMAssay Description:In vitro antagonist activity against rat prostatic androgen receptor (AR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM48320(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM50238827(CHEMBL4064328)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM50489048(CHEMBL2299190)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM50489044(CHEMBL2299191)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM50489043(CHEMBL2299192)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM217354(2-(3,5-bistrifluoromethylbenzylamino)-6-oxo-1H-pyr...)
Affinity DataIC50:  6.30E+3nMAssay Description:The halogenation activities of LPO (EC 1.11.1.7) and TPO (EC 1.11.1.8) were determined using a modified method of that described previously [Ferrari ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50507390(CHEMBL4482878 | US10981879, Example 3)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of human LPO assessed as reduction in H2O2 catalyzed 3,5-iodo tyrosine formation from 3-iodotyrosine and potassium iodide preincubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM50241361(CHEMBL1515 | METHIMAZOLE | US9138393, Methimazole ...)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM50489045(CHEMBL2299193)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetLactoperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50275890(CHEMBL457523 | ethyl 2,3-dihydro-3-methyl-2-seleno...)
Affinity DataIC50:  1.01E+4nMAssay Description:Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50275889(CHEMBL508102 | carbimazole)
Affinity DataIC50:  1.04E+4nMAssay Description:Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50275891(CHEMBL444464 | methyl 3-methyl-2-thioxo-2,3-dihydr...)
Affinity DataIC50:  1.07E+4nMAssay Description:Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50241361(CHEMBL1515 | METHIMAZOLE | US9138393, Methimazole ...)
Affinity DataIC50:  1.18E+4nMAssay Description:Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM50489042(CHEMBL2295876)
Affinity DataIC50:  1.39E+4nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM50489049(CHEMBL2299195)
Affinity DataIC50:  1.43E+4nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM50489046(CHEMBL2299198)
Affinity DataIC50:  1.74E+4nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM50489041(CHEMBL2299196)
Affinity DataIC50:  1.78E+4nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM7458(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50:  1.78E+4nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50275895(CHEMBL469530 | methyl 3-ethyl-2-thioxo-2,3-dihydro...)
Affinity DataIC50:  1.96E+4nMAssay Description:Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50275892(CHEMBL507966 | methyl 3-methyl-2-selenoxo-2,3-dihy...)
Affinity DataIC50:  1.97E+4nMAssay Description:Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50275893(CHEMBL469529 | ethyl 3-ethyl-2-thioxo-2,3-dihydro-...)
Affinity DataIC50:  2.05E+4nMAssay Description:Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50275894(CHEMBL446332 | ethyl 3-ethyl-2-selenoxo-2,3-dihydr...)
Affinity DataIC50:  2.13E+4nMAssay Description:Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM50489039(CHEMBL2299199)
Affinity DataIC50:  2.19E+4nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetLactoperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50275944(CHEMBL459114 | methyl 3-ethyl-2-selenoxo-2,3-dihyd...)
Affinity DataIC50:  2.53E+4nMAssay Description:Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM50489047(CHEMBL2299194)
Affinity DataIC50:  2.64E+4nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM50489040(CHEMBL2299197)
Affinity DataIC50:  2.65E+4nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM50489038(CHEMBL2299200)
Affinity DataIC50:  3.46E+4nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetLactoperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50554034(CHEMBL4747269)
Affinity DataIC50: >6.20E+4nMAssay Description:Inhibition of LPO (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetLactoperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50554035(CHEMBL4790231)
Affinity DataIC50: >6.20E+4nMAssay Description:Inhibition of LPO (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM50489050(CHEMBL2299201)
Affinity DataIC50:  9.38E+4nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetLactoperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50106515(7-Benzyloxy-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-y...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human LPO assessed as reduction in H2O2 catalyzed 3,5-iodo tyrosine formation from 3-iodotyrosine and potassium iodide preincubated for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM50489036(CHEMBL2299202)
Affinity DataIC50:  1.05E+5nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM50207306(CHEMBL2140153)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM114830(3-(4-methoxyphenyl)-1H-isochromen-1-one | 3-(4-met...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM50489037(CHEMBL2299203)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article