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Found 4 Enz. Inhib. hit(s) with Target = 'Mast/stem cell growth factor receptor Kit [V560G]'
TargetMast/stem cell growth factor receptor Kit [V560G](Homo sapiens (Human))
Blueprint Medicines

US Patent
LigandPNGBDBM504397((S)-1-(4-fluorophenyl)-1-(2-(4-(6-(1-methyl-1H-pyr...)
Affinity DataIC50:  5.5nMAssay Description:KIT, KIT mutant, and PDGFRα mutant kinase profiling was performed with recombinant enzymes including wild-type KIT, KIT V560G, KIT V559D/T670I, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit [V560G](Homo sapiens (Human))
Blueprint Medicines

US Patent
LigandPNGBDBM504400((S)-4-(4-(5-(1-amino-1-(4-fluorophenyl)ethyl)pyrim...)
Affinity DataIC50:  5.5nMAssay Description:KIT, KIT mutant, and PDGFRα mutant kinase profiling was performed with recombinant enzymes including wild-type KIT, KIT V560G, KIT V559D/T670I, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit [V560G](Homo sapiens (Human))
Blueprint Medicines

US Patent
LigandPNGBDBM504399((S)-1-(2-(4-(3-chloro-6-(1-methyl-1H-pyrazol-4-yl)...)
Affinity DataIC50:  55nMAssay Description:KIT, KIT mutant, and PDGFRα mutant kinase profiling was performed with recombinant enzymes including wild-type KIT, KIT V560G, KIT V559D/T670I, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit [V560G](Homo sapiens (Human))
Blueprint Medicines

US Patent
LigandPNGBDBM504398((S)-1-(2-(4-(3-fluoro-6-(1-methyl-11H-pyrazol-4-yl...)
Affinity DataIC50:  55nMAssay Description:KIT, KIT mutant, and PDGFRα mutant kinase profiling was performed with recombinant enzymes including wild-type KIT, KIT V560G, KIT V559D/T670I, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent