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Found 95 Enz. Inhib. hit(s) with Target = 'Nucleosome-remodeling factor subunit BPTF'
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50443230(CHEMBL3086885)
Affinity DataKi:  1.62E+3nMAssay Description:Displacement of fluorescein-labeled MS239 from recombinant human BPTF after 1 hr by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50443232(CHEMBL3086883)
Affinity DataKi:  6.06E+3nMAssay Description:Displacement of fluorescein-labeled MS239 from recombinant human BPTF after 1 hr by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573840(CHEMBL4860578)
Affinity DataIC50:  16nMAssay Description:Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50571296(CHEMBL4873093)
Affinity DataIC50:  16nMAssay Description:Inhibition of BPTF in human HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573844(CHEMBL4873042)
Affinity DataIC50:  27nMAssay Description:Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assayMore data for this Ligand-Target Pair
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573839(CHEMBL4870170)
Affinity DataIC50:  29nMAssay Description:Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50571296(CHEMBL4873093)
Affinity DataIC50:  30nMAssay Description:Inhibition of BPTF (unknown origin) by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573837(CHEMBL4867072)
Affinity DataIC50:  33nMAssay Description:Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573200(CHEMBL4861491)
Affinity DataIC50:  36nMAssay Description:Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573838(CHEMBL4868713)
Affinity DataIC50:  37nMAssay Description:Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573201(CHEMBL4848701)
Affinity DataIC50:  56nMAssay Description:Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573845(CHEMBL4851594)
Affinity DataIC50:  59nMAssay Description:Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573849(CHEMBL4866637)
Affinity DataIC50:  59nMAssay Description:Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573848(CHEMBL4862619)
Affinity DataIC50:  64nMAssay Description:Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573197(CHEMBL4872300)
Affinity DataIC50:  67nMAssay Description:Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573841(CHEMBL4852588)
Affinity DataIC50:  114nMAssay Description:Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573846(CHEMBL4853486)
Affinity DataIC50:  145nMAssay Description:Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573850(CHEMBL4861221)
Affinity DataIC50:  157nMAssay Description:Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573198(CHEMBL4848138)
Affinity DataIC50:  170nMAssay Description:Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50234940(CHEMBL4101756)
Affinity DataIC50:  220nMAssay Description:Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573192(CHEMBL4850516)
Affinity DataIC50:  250nMAssay Description:Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573842(CHEMBL4863921)
Affinity DataIC50:  288nMAssay Description:Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573190(CHEMBL4866748)
Affinity DataIC50:  290nMAssay Description:Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573191(CHEMBL4870218)
Affinity DataIC50:  310nMAssay Description:Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50514899(CHEMBL4461619)
Affinity DataIC50:  350nMAssay Description:Inhibition of BPTF (unknown origin) by AlphaScreen assayMore data for this Ligand-Target Pair
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573193(CHEMBL4848082)
Affinity DataIC50:  370nMAssay Description:Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573203(CHEMBL4863631)
Affinity DataIC50:  380nMAssay Description:Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573202(CHEMBL4877696)
Affinity DataIC50:  550nMAssay Description:Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573836(CHEMBL4861375)
Affinity DataIC50:  698nMAssay Description:Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assayMore data for this Ligand-Target Pair
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573188(CHEMBL4850913)
Affinity DataIC50:  700nMAssay Description:Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573204(CHEMBL4863529)
Affinity DataIC50:  790nMAssay Description:Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573195(CHEMBL4855881)
Affinity DataIC50:  800nMAssay Description:Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50234924(CHEMBL4065579)
Affinity DataIC50:  950nMAssay Description:Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573196(CHEMBL4877118)
Affinity DataIC50:  970nMAssay Description:Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50157606(CHEMBL3785432)
Affinity DataIC50:  1.46E+3nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) preincubated for 15 mins followed by addition of C-terminal biotinylated synthetic K5,8,12,16 tetra-acetylate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50234923(CHEMBL4069412)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573835(CHEMBL4872350)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573847(CHEMBL4872974)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573187(CHEMBL4861822)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573194(CHEMBL4858548)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573186(CHEMBL4872107)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573834(CHEMBL4863800)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573185(CHEMBL4853420)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573199(CHEMBL4849136)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573183(CHEMBL4867912)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573189(CHEMBL4857332)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50571298(CHEMBL4846726)
Affinity DataIC50:  1.32E+4nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant BPTF expressed in Escherichia coli BL21-Codonplus (DE3)-RIPL incubated for 30 mins by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50573843(CHEMBL4875586)
Affinity DataIC50:  1.47E+4nMAssay Description:Inhibition of N-terminal GST-tagged human BPTF (2914 to 3037 residues) expressed in Escherichia coli BL21-CodonPlus (DE3) cells by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50558065(CHEMBL4780530)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of BPTF (unknown origin) measured after 70 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetNucleosome-remodeling factor subunit BPTF(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50234944(CHEMBL4072538 | US10239861, Example 60)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
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