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Found 214 Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 1'
TargetP2X purinoceptor 1(RAT)
Biocentre Niederursel

Curated by PDSP Ki Database
LigandPNGBDBM50000029(4-Methyl-8-{4-methyl-3-[3-(3-{3-[2-methyl-5-(4,6,8...)
Affinity DataKi:  50nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
Biocentre Niederursel

Curated by PDSP Ki Database
LigandPNGBDBM85730(CAS_5311313 | NF023 | NSC_5311313)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50171290(5-(4-Bromo-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM85682(CAS_5311315 | NF279 | NSC_5311315)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
Biocentre Niederursel

Curated by PDSP Ki Database
LigandPNGBDBM85682(CAS_5311315 | NF279 | NSC_5311315)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50000029(4-Methyl-8-{4-methyl-3-[3-(3-{3-[2-methyl-5-(4,6,8...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM21280(5-(4-chloro-3-methylphenyl)-1-[(4-methylphenyl)met...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetP2X purinoceptor 1(RAT)
Biocentre Niederursel

Curated by PDSP Ki Database
LigandPNGBDBM50240455(CHEMBL1253351)
Affinity DataIC50:  0.280nMAssay Description:Antagonist activity at rat P2X1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM526264(US11185100, TABLE 14.4)
Affinity DataIC50:  3.5nMAssay Description:Agonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 1(RAT)
Biocentre Niederursel

Curated by PDSP Ki Database
LigandPNGBDBM50540410(CHEMBL337395)
Affinity DataIC50:  6nMAssay Description:Antagonist activity at rat P2X1 receptorMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
Biocentre Niederursel

Curated by PDSP Ki Database
LigandPNGBDBM50102298(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonomethyl-p...)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
Biocentre Niederursel

Curated by PDSP Ki Database
LigandPNGBDBM50102295(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50:  9.40nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
Biocentre Niederursel

Curated by PDSP Ki Database
LigandPNGBDBM50102299(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonomethyl-p...)
Affinity DataIC50:  11nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
Biocentre Niederursel

Curated by PDSP Ki Database
LigandPNGBDBM50102300(CHEMBL331250 | [4-(4-Formyl-5-hydroxy-6-methyl-3-p...)
Affinity DataIC50:  12nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
Biocentre Niederursel

Curated by PDSP Ki Database
LigandPNGBDBM50118221(9H-purine derivative | CHEMBL132722 | DIPHOSPHOMET...)
Affinity DataIC50:  14nMAssay Description:Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50430160(CHEMBL536151 | TCMDC-125465)
Affinity DataIC50:  19nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
Biocentre Niederursel

Curated by PDSP Ki Database
LigandPNGBDBM50102301(4-[4-Formyl-5-hydroxy-6-methyl-3-(2-phosphono-ethy...)
Affinity DataIC50:  20nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50430195(CHEMBL2338696)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50430185(CHEMBL2179173)
Affinity DataIC50:  29nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Mus musculus)
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50102295(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50:  30nMAssay Description:Antagonist activity at recombinant mouse P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Mus musculus)
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50064800(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50:  31nMAssay Description:Antagonist activity at mouse recombinant P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current incubated for 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50540434(CHEMBL4640175)
Affinity DataIC50:  32nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
Biocentre Niederursel

Curated by PDSP Ki Database
LigandPNGBDBM50102296(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonomethyl-p...)
Affinity DataIC50:  37nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50430177(CHEMBL2088014)
Affinity DataIC50:  38nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
Biocentre Niederursel

Curated by PDSP Ki Database
LigandPNGBDBM50102297(CHEMBL118007 | [2-(3,5-Bis-phosphonomethyl-phenyla...)
Affinity DataIC50:  42nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
Biocentre Niederursel

Curated by PDSP Ki Database
LigandPNGBDBM50102304(CHEMBL116926 | Phosphoric acid mono-(4-formyl-5-hy...)
Affinity DataIC50:  42nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
Biocentre Niederursel

Curated by PDSP Ki Database
LigandPNGBDBM50102295(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50:  43nMAssay Description:Antagonist activity at recombinant rat P2X1 receptor expressed in Xenopus oocytes assessed as ion flux stimulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
Biocentre Niederursel

Curated by PDSP Ki Database
LigandPNGBDBM50064800(2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50:  43nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50540436(CHEMBL2179174)
Affinity DataIC50:  51nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50430156(CHEMBL2338695)
Affinity DataIC50:  58nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50422739(CHEMBL413145)
Affinity DataIC50:  63nMAssay Description:Inhibitory concentration against human P2X purinoceptor 1 expressed in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Mus musculus)
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50433072(CHEMBL2376126)
Affinity DataIC50:  71nMAssay Description:Antagonist activity at mouse recombinant P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current incubated for 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50540422(CHEMBL4644398)
Affinity DataIC50:  71nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50540442(CHEMBL2088011)
Affinity DataIC50:  76nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50430159(CHEMBL461542)
Affinity DataIC50:  77nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50430176(CHEMBL589733 | MMV665807 | SJ000010289)
Affinity DataIC50:  91nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(RAT)
Biocentre Niederursel

Curated by PDSP Ki Database
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)
Affinity DataIC50:  99nMAssay Description:Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Mus musculus)
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)
Affinity DataIC50:  99nMAssay Description:Antagonist activity at mouse P2X1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50540410(CHEMBL337395)
Affinity DataIC50:  120nMAssay Description:Antagonist activity at human P2X1R transfected in CHO-K1 cells preincubated for 30 mins followed by alpha,beta-meATP addition by luminescence based a...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 1(Mus musculus)
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50433071(CHEMBL2376118)
Affinity DataIC50:  130nMAssay Description:Antagonist activity at mouse recombinant P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current incubated for 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50540439(CHEMBL2088009)
Affinity DataIC50:  172nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50015276(CHEMBL3263056 | US9428504, 166 | US9428504, 167)
Affinity DataIC50:  180nMAssay Description:Antagonist activity at P2X1 receptor (unknown origin) by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50540432(CHEMBL2088012)
Affinity DataIC50:  199nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50118228(5,7-Disulfo-4-(3-{3-[3-(4,6,8-trisulfo-naphthalen-...)
Affinity DataIC50:  210nMAssay Description:The compound was evaluated for antagonist activity against recombinant human P2X purinoceptor 1 (P2X1 )More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50540449(CHEMBL4637528)
Affinity DataIC50:  219nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50430194(CHEMBL2313115)
Affinity DataIC50:  236nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50240455(CHEMBL1253351)
Affinity DataIC50:  236nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Mus musculus)
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50444432(CHEMBL3091610)
Affinity DataIC50:  267nMAssay Description:Antagonist activity at recombinant mouse P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50430186(CHEMBL2178702)
Affinity DataIC50:  323nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Homo sapiens (Human))
Sanofi-Synthelabo Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50540443(CHEMBL4648128)
Affinity DataIC50:  335nMAssay Description:Antagonist activity at non-desensitizing human P2X1 receptor ( P2X2/P2X1 chimera) expressed in human 1321N1 cells assessed as inhibition of ATP-induc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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