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Found 3 Enz. Inhib. hit(s) with Target = 'POU domain, class 2, transcription factor 1'
TargetPOU domain, class 2, transcription factor 1(Homo sapiens (Human))
Nippon Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50228403((R)-8-(3-aminopiperidin-1-yl)-7-(but-2-ynyl)-3-met...)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of OCT1 (unknown origin) expressed in HEK293 cells assessed as reduction of [14C]metformin substrate uptake at 100 uM by liquid scintillat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPOU domain, class 2, transcription factor 1(Homo sapiens (Human))
Nippon Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50228403((R)-8-(3-aminopiperidin-1-yl)-7-(but-2-ynyl)-3-met...)
Affinity DataIC50:  4.50E+4nMAssay Description:Inhibition of OCT1 (unknown origin) expressed in HEK293 cells assessed as reduction of [ethyl 1-14C]TEA substrate uptake at 100 uM by liquid scintill...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPOU domain, class 2, transcription factor 1(Homo sapiens (Human))
Nippon Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50576849(CHEMBL4876008)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of OCT1 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed