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Found 875 Enz. Inhib. hit(s) with Target = 'Serine protease HTRA1'
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521765(US11149067, Compound Ahp26)
Affinity DataKi:  65nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521770(US11149067, Compound Ahp33)
Affinity DataKi:  610nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521764(US11149067, Compound Ahp25)
Affinity DataKi:  700nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521766(US11149067, Compound Ahp27)
Affinity DataKi:  950nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521759(US11149067, Compound Ahp19)
Affinity DataKi:  1.24E+3nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521773(US11149067, Compound Ahp36)
Affinity DataKi:  1.40E+3nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521774(US11149067, Compound Ahp37)
Affinity DataKi:  1.40E+3nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521763(US11149067, Compound Ahp24)
Affinity DataKi:  1.66E+3nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521768(US11149067, Compound Ahp29)
Affinity DataKi:  1.80E+3nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521751(US11149067, Compound Ahp10)
Affinity DataKi:  2.40E+3nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521767(US11149067, Compound Ahp28)
Affinity DataKi:  2.80E+3nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521754(US11149067, Compound Ahp14)
Affinity DataKi:  2.97E+3nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521769(US11149067, Compound Ahp30)
Affinity DataKi:  3.00E+3nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521753(US11149067, Compound Ahp13)
Affinity DataKi:  4.26E+3nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521762(US11149067, Compound Ahp22)
Affinity DataKi:  5.20E+3nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521772(US11149067, Compound Ahp35)
Affinity DataKi:  6.30E+3nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521755(US11149067, Compound Ahp15)
Affinity DataKi:  7.00E+3nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521742(US11149067, Compound Ahp1)
Affinity DataKi:  8.20E+3nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521747(US11149067, Compound Ahp6)
Affinity DataKi:  1.03E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521771(US11149067, Compound Ahp34)
Affinity DataKi:  4.34E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521761(US11149067, Compound Ahp21)
Affinity DataKi: >5.00E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521760(US11149067, Compound Ahp20)
Affinity DataKi: >5.00E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521758(US11149067, Compound Ahp18)
Affinity DataKi: >5.00E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521757(US11149067, Compound Ahp17)
Affinity DataKi: >5.00E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521756(US11149067, Compound Ahp16)
Affinity DataKi: >5.00E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521752(US11149067, Compound Ahp11)
Affinity DataKi: >5.00E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521750(US11149067, Compound Ahp9)
Affinity DataKi: >5.00E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521749(US11149067, Compound Ahp8)
Affinity DataKi: >5.00E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521748(US11149067, Compound Ahp7)
Affinity DataKi: >5.00E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521746(US11149067, Compound Ahp5)
Affinity DataKi: >5.00E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521745(US11149067, Compound Ahp4)
Affinity DataKi: >5.00E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521744(US11149067, Compound Ahp3)
Affinity DataKi: >5.00E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1 [158-480](Homo sapiens (Human))
UniversitÄT Duisburg-Essen

US Patent
LigandPNGBDBM521743(US11149067, Compound Ahp2)
Affinity DataKi: >5.00E+4nMAssay Description:In general, proteolytic activity was tested by monitoring the cleavage of the specific chromogenic substrate at 405 nm wavelength for 60 or 120 minut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM496984(US11001555, Example 7)
Affinity DataIC50:  0.262nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM475923((4S)-4-[[(2S)-2-[[(2R)-2- (3-chloro-5- cyanophenox...)
Affinity DataIC50:  0.293nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM514085(US11059858, Example 42)
Affinity DataIC50:  0.300nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM514094(US11059858, Example 48)
Affinity DataIC50:  0.300nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM514076(US11059858, Example 33)
Affinity DataIC50:  0.300nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM496983(US11001555, Example 6)
Affinity DataIC50:  0.351nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM499311(US11014963, Example 216)
Affinity DataIC50:  0.400nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM514056(US11059858, Example 15)
Affinity DataIC50:  0.400nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM514098(N-[(2S)-3-(3-Chlorophenyl)-1-[[(1S)-2-[[(3S)-5,5-d...)
Affinity DataIC50:  0.400nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM514090(US11059858, Example 44)
Affinity DataIC50:  0.400nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM514091(US11059858, Example 45)
Affinity DataIC50:  0.400nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM514104(US11059858, Example 58)
Affinity DataIC50:  0.400nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM475927((4S)-4-[[(2S)-2-[[(2R)-2- (3-chlorophenoxy)-3-(3- ...)
Affinity DataIC50:  0.461nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM496981(US11001555, Example 4)
Affinity DataIC50:  0.471nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM499107(US11014963, Example 17)
Affinity DataIC50:  0.490nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM514102(US11059858, Example 56)
Affinity DataIC50:  0.5nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM514057(US11059858, Example 16)
Affinity DataIC50:  0.5nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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