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Found 274 Enz. Inhib. hit(s) with Target = '1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1'
LigandPNGBDBM50037076(CHEMBL3355737)
Affinity DataIC50:  180nMAssay Description:Inhibition of PLC gamma-1 phosphorylation in human Jurkat T cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50037063(CHEMBL3355726)
Affinity DataIC50:  540nMAssay Description:Inhibition of PLC gamma-1 phosphorylation in human Jurkat T cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM100881(US9695200, 67)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM103397(US9695200, 72)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM107352(US9695200, 74)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM107952(US9695200, 76)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM108039(US9695200, 80)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM108388(US9695200, 89)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM108763(US9695200, 91)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM99857(US9695200, 59)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM100765(US9695200, 61)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM100784(US9695200, 62)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM99847(US9695200, 57)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM99790(US9695200, 50)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM81141(US9695200, 6)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM87738(US9695200, 11)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM88535(US9695200, 20)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM88551(US9695200, 22)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM88562(US9695200, 24)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM88653(US9695200, 25)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM88670(US9695200, 26)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM98760(US9695200, 28)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM98786(US9695200, 32)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM98821(US9695200, 41)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM99737(US9695200, 46)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM99786(US9695200, 49)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [1-999,I813T](Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM84007(CEFIXIME | Cefiximum [Latin] | MLS002222332 | SMR0...)
Affinity DataIC50:  1.21E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute Ass...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [1-999,I813T](Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM52817(2-[(5Z)-5-[(E)-3-(2-furanyl)prop-2-enylidene]-4-ox...)
Affinity DataIC50:  1.51E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute Ass...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [1-999,I813T](Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM34905(1,6-dimethyl-3-propyl-pyrimido[5,4-e][1,2,4]triazi...)
Affinity DataIC50:  1.51E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute Ass...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [1-999,I813T](Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM114297(2-[(3R,6S)-1-acetyl-6-(tosylcarbamoyl)-3,6-dihydro...)
Affinity DataIC50:  2.03E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute Ass...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [1-999,I813T](Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM18136(ADP, alpha beta-me | AMPCPP | [({[(2R,3S,4R,5R)-5-...)
Affinity DataIC50:  2.20E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute Ass...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1(Bos taurus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50259930(6-(10'Z-heptadecenyl)-salicylicacid | 6-[10'(Z)-he...)
Affinity DataIC50:  2.22E+3nMAssay Description:Inhibition of bovine brain PI-PLCgamma1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50037060(CHEMBL3355311)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of PLC gamma-1 phosphorylation in human Jurkat T cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [1-999,I813T](Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM114292(2-(2-cyano-3-pyridinyl)-2-methylpropanoic acid met...)
Affinity DataIC50:  2.70E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute Ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PCBioAssay
LigandPNGBDBM100840(US9695200, 64)
Affinity DataIC50:  3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM99852(US9695200, 58)
Affinity DataIC50:  3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM102354(US9695200, 71)
Affinity DataIC50:  3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM108346(US9695200, 83)
Affinity DataIC50:  3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM108352(US9695200, 84)
Affinity DataIC50:  3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM108382(US9695200, 88)
Affinity DataIC50:  3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM108810(US9695200, 92)
Affinity DataIC50:  3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM81238(US9695200, 8)
Affinity DataIC50:  3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM87754(US9695200, 12)
Affinity DataIC50:  3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM88537(US9695200, 21)
Affinity DataIC50:  3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM88558(US9695200, 23)
Affinity DataIC50:  3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM98772(US9695200, 29)
Affinity DataIC50:  3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM98779(US9695200, 30)
Affinity DataIC50:  3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM98793(US9695200, 33)
Affinity DataIC50:  3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM98807(US9695200, 37)
Affinity DataIC50:  3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM98813(US9695200, 39)
Affinity DataIC50:  3.00E+3nMT: 2°CAssay Description:Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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