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Found 17 Enz. Inhib. hit(s) with Target = 'C-C motif chemokine 4'
TargetC-C motif chemokine 4(Homo sapiens (Human))
Celgene

US Patent
LigandPNGBDBM77015((R)-3-(4-((4-(morpholinomethyl)benzyl)-oxy)-1-oxoi...)
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a â¿¿20° C. freezer p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C motif chemokine 4(Homo sapiens (Human))
Celgene

US Patent
LigandPNGBDBM77001(3-(4-((4-(morpholinomethyl)benzyl)-oxy)-1-oxoisoin...)
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a â¿¿20° C. freezer p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C motif chemokine 4(Homo sapiens (Human))
Celgene

US Patent
LigandPNGBDBM65454(191732-72-6 | CC-5013 | Lenalidomide | Revimid | R...)
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a â¿¿20° C. freezer p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C motif chemokine 4(Homo sapiens (Human))
Celgene

US Patent
LigandPNGBDBM65456(19171-19-8 | 4-amino-2-(2,6-dioxopiperidin-3-yl)is...)
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a â¿¿20° C. freezer p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C motif chemokine 4(Homo sapiens (Human))
Celgene

US Patent
LigandPNGBDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a â¿¿20° C. freezer p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C motif chemokine 4(Homo sapiens (Human))
Celgene

US Patent
LigandPNGBDBM76986(3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-pipe...)
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a â¿¿20° C. freezer p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C motif chemokine 4(Homo sapiens (Human))
Celgene

US Patent
LigandPNGBDBM65497(CC-220 (Compound 6) | US9694015, 6.4S)
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a â¿¿20° C. freezer p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetC-C motif chemokine 4(Rat)
Inimmune

US Patent
LigandPNGBDBM633253(Preparation of N—[(R)-3-Decanoyloxytetradecanoyl]-...)
Affinity DataEC50:  0.0110nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C motif chemokine 4(Rat)
Inimmune

US Patent
LigandPNGBDBM633254(Preparation of N—[(R)-3-Decyloxytetradecanoyl]-O-[...)
Affinity DataEC50:  0.00100nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C motif chemokine 4(Rat)
Inimmune

US Patent
LigandPNGBDBM633252(Preparation of 2-[(R)-3-decanoyloxytetradecanoylam...)
Affinity DataEC50:  0.0180nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C motif chemokine 4(Rat)
Inimmune

US Patent
LigandPNGBDBM633251(Preparation of 2-[(R)-3-decanoyloxytetradecanoylam...)
Affinity DataEC50:  0.0580nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C motif chemokine 4(Homo sapiens (Human))
Celgene

US Patent
LigandPNGBDBM633255(GLA | Glycopyranoside Lipid A | MPLA | Monophospho...)
Affinity DataEC50:  3.10nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C motif chemokine 4(Homo sapiens (Human))
Celgene

US Patent
LigandPNGBDBM633254(Preparation of N—[(R)-3-Decyloxytetradecanoyl]-O-[...)
Affinity DataEC50:  0.124nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C motif chemokine 4(Homo sapiens (Human))
Celgene

US Patent
LigandPNGBDBM633253(Preparation of N—[(R)-3-Decanoyloxytetradecanoyl]-...)
Affinity DataEC50:  0.462nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C motif chemokine 4(Rat)
Inimmune

US Patent
LigandPNGBDBM633255(GLA | Glycopyranoside Lipid A | MPLA | Monophospho...)
Affinity DataEC50:  0.258nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C motif chemokine 4(Homo sapiens (Human))
Celgene

US Patent
LigandPNGBDBM633251(Preparation of 2-[(R)-3-decanoyloxytetradecanoylam...)
Affinity DataEC50:  0.251nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C motif chemokine 4(Homo sapiens (Human))
Celgene

US Patent
LigandPNGBDBM633252(Preparation of 2-[(R)-3-decanoyloxytetradecanoylam...)
Affinity DataEC50:  5.89nMAssay Description:In vitro assays were conducted with Compounds 1-9 and the commercially available TLR4 agonist MPL. For measurement of biological activity various cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent