TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Inhibition of Bacillus anthracis edema factor catalytic domain by radiometric assayMore data for this Ligand-Target Pair
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Inactivation of Bacillus anthracis edema factor in presence of CaM incubated for 10 to 240 mins by EnzChek pyrophosphate assayMore data for this Ligand-Target Pair
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Affinity DataKi: 700nMAssay Description:Inactivation of Bacillus anthracis edema factor in presence of CaM incubated for 10 to 240 mins by EnzChek pyrophosphate assayMore data for this Ligand-Target Pair
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Affinity DataKi: 980nMAssay Description:Inhibition of Bacillus anthracis edema factor catalytic domain by radiometric assayMore data for this Ligand-Target Pair
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Affinity DataKi: 2.10E+3nMAssay Description:Inactivation of Bacillus anthracis edema factor in presence of CaM incubated for 10 to 240 mins by EnzChek pyrophosphate assayMore data for this Ligand-Target Pair
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Affinity DataKi: 3.70E+3nMAssay Description:Inactivation of Bacillus anthracis edema factor in presence of CaM incubated for 10 to 240 mins by EnzChek pyrophosphate assayMore data for this Ligand-Target Pair
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Affinity DataKi: 4.60E+3nMAssay Description:Inactivation of Bacillus anthracis edema factor in presence of CaM incubated for 10 to 240 mins by EnzChek pyrophosphate assayMore data for this Ligand-Target Pair
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Affinity DataKi: 8.98E+3nMAssay Description:Inhibition of Bacillus anthracis edema factor catalytic domain by radiometric assayMore data for this Ligand-Target Pair
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Affinity DataKi: 9.40E+3nMAssay Description:Inactivation of Bacillus anthracis edema factor in presence of CaM incubated for 10 to 240 mins by EnzChek pyrophosphate assayMore data for this Ligand-Target Pair
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Affinity DataKi: 1.09E+4nMAssay Description:Inactivation of Bacillus anthracis edema factor in presence of CaM incubated for 10 to 240 mins by EnzChek pyrophosphate assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.39E+4nMAssay Description:Inhibition of recombinant calmodulin (unknown origin) mediated bovine brain PDE1 activation assessed as effect on inorganic phosphate release using v...More data for this Ligand-Target Pair
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Affinity DataKi: 1.47E+4nMAssay Description:Inactivation of Bacillus anthracis edema factor in presence of CaM incubated for 10 to 240 mins by EnzChek pyrophosphate assayMore data for this Ligand-Target Pair
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Affinity DataKi: 1.65E+4nMAssay Description:Inactivation of Bacillus anthracis edema factor in presence of CaM incubated for 10 to 240 mins by EnzChek pyrophosphate assayMore data for this Ligand-Target Pair
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Affinity DataKi: 1.84E+4nMAssay Description:Inactivation of Bacillus anthracis edema factor in presence of CaM incubated for 10 to 240 mins by EnzChek pyrophosphate assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.93E+4nMAssay Description:Inhibition of recombinant calmodulin (unknown origin) mediated bovine brain PDE1 activation assessed as effect on inorganic phosphate release using v...More data for this Ligand-Target Pair
Affinity DataKi: 2.54E+4nMAssay Description:Inhibition of recombinant calmodulin (unknown origin) mediated bovine brain PDE1 activation assessed as effect on inorganic phosphate release using v...More data for this Ligand-Target Pair
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Affinity DataKi: 2.59E+4nMAssay Description:Inactivation of Bacillus anthracis edema factor in presence of CaM incubated for 10 to 240 mins by EnzChek pyrophosphate assayMore data for this Ligand-Target Pair
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Affinity DataKi: 2.76E+4nMAssay Description:Inactivation of Bacillus anthracis edema factor in presence of CaM incubated for 10 to 240 mins by EnzChek pyrophosphate assayMore data for this Ligand-Target Pair
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Affinity DataKi: 3.48E+4nMAssay Description:Inactivation of Bacillus anthracis edema factor in presence of CaM incubated for 10 to 240 mins by EnzChek pyrophosphate assayMore data for this Ligand-Target Pair
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Affinity DataKi: 3.77E+4nMAssay Description:Inactivation of Bacillus anthracis edema factor in presence of CaM incubated for 10 to 240 mins by EnzChek pyrophosphate assayMore data for this Ligand-Target Pair
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Affinity DataKi: 3.89E+4nMAssay Description:Inactivation of Bacillus anthracis edema factor in presence of CaM incubated for 10 to 240 mins by EnzChek pyrophosphate assayMore data for this Ligand-Target Pair
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Affinity DataKi: 4.22E+4nMAssay Description:Inactivation of Bacillus anthracis edema factor in presence of CaM incubated for 10 to 240 mins by EnzChek pyrophosphate assayMore data for this Ligand-Target Pair
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Affinity DataKi: 4.96E+4nMAssay Description:Inactivation of Bacillus anthracis edema factor in presence of CaM incubated for 10 to 240 mins by EnzChek pyrophosphate assayMore data for this Ligand-Target Pair
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Affinity DataKi: 5.91E+4nMAssay Description:Inactivation of Bacillus anthracis edema factor in presence of CaM incubated for 10 to 240 mins by EnzChek pyrophosphate assayMore data for this Ligand-Target Pair
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Affinity DataKi: 8.81E+4nMAssay Description:Inactivation of Bacillus anthracis edema factor in presence of CaM incubated for 10 to 240 mins by EnzChek pyrophosphate assayMore data for this Ligand-Target Pair
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Affinity DataKi: 9.65E+4nMAssay Description:Inactivation of Bacillus anthracis edema factor in presence of CaM incubated for 10 to 240 mins by EnzChek pyrophosphate assayMore data for this Ligand-Target Pair
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Affinity DataKi: 1.27E+5nMAssay Description:Inactivation of Bacillus anthracis edema factor in presence of CaM incubated for 10 to 240 mins by EnzChek pyrophosphate assayMore data for this Ligand-Target Pair
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Affinity DataKi: 2.22E+5nMAssay Description:Inactivation of Bacillus anthracis edema factor in presence of CaM incubated for 10 to 240 mins by EnzChek pyrophosphate assayMore data for this Ligand-Target Pair
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Affinity DataKi: 2.86E+5nMAssay Description:Inactivation of Bacillus anthracis edema factor in presence of CaM incubated for 10 to 240 mins by EnzChek pyrophosphate assayMore data for this Ligand-Target Pair
TargetCalmodulin-sensitive adenylate cyclase(Bacillus anthracis)
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Ernst-Moritz-Arndt-University
Curated by ChEMBL
Affinity DataKi: 9.55E+5nMAssay Description:Inactivation of Bacillus anthracis edema factor in presence of CaM incubated for 10 to 240 mins by EnzChek pyrophosphate assayMore data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1, putative(Cryptosporidium parvum (strain Iowa II))
University Of Washington Through Its Center For
US Patent
University Of Washington Through Its Center For
US Patent
Affinity DataIC50: 0.400nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1, putative(Cryptosporidium parvum (strain Iowa II))
University Of Washington Through Its Center For
US Patent
University Of Washington Through Its Center For
US Patent
Affinity DataIC50: 0.600nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University Of Washington Through Its Center For
US Patent
University Of Washington Through Its Center For
US Patent
Affinity DataIC50: 0.600nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University Of Washington Through Its Center For
US Patent
University Of Washington Through Its Center For
US Patent
Affinity DataIC50: 0.600nMAssay Description:Most known kinase inhibitors bind in the ATP-binding pocket of the active site19,20. These inhibitors exploit many of the same hydrophobic contacts a...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University Of Washington Through Its Center For
US Patent
University Of Washington Through Its Center For
US Patent
Affinity DataIC50: 0.700nMAssay Description:Inhibitors were evaluated in triplicate in eight-point dilutions (3-fold dilutions) during the enzymatic reactions. TgCDPK1 enzymatic inhibition was ...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University Of Washington Through Its Center For
US Patent
University Of Washington Through Its Center For
US Patent
Affinity DataIC50: 0.700nMAssay Description:Inhibitors were evaluated in triplicate in eight-point dilutions (3-fold dilutions) during the enzymatic reactions. TgCDPK1 enzymatic inhibition was ...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University Of Washington Through Its Center For
US Patent
University Of Washington Through Its Center For
US Patent
Affinity DataIC50: 0.700nMAssay Description:Most known kinase inhibitors bind in the ATP-binding pocket of the active site19,20. These inhibitors exploit many of the same hydrophobic contacts a...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University Of Washington Through Its Center For
US Patent
University Of Washington Through Its Center For
US Patent
Affinity DataIC50: 0.700nMAssay Description:Most known kinase inhibitors bind in the ATP-binding pocket of the active site19,20. These inhibitors exploit many of the same hydrophobic contacts a...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University Of Washington Through Its Center For
US Patent
University Of Washington Through Its Center For
US Patent
Affinity DataIC50: 0.700nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University Of Washington Through Its Center For
US Patent
University Of Washington Through Its Center For
US Patent
Affinity DataIC50: 0.700nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University Of Washington Through Its Center For
US Patent
University Of Washington Through Its Center For
US Patent
Affinity DataIC50: 0.800nMAssay Description:Inhibition of recombinant Toxoplasma gondii CDPK1 using Biotin-C6-PLARTLSVAGLPGKK as substrate after 90 mins in presence of ATP by luciferase reporte...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1, putative(Cryptosporidium parvum (strain Iowa II))
University Of Washington Through Its Center For
US Patent
University Of Washington Through Its Center For
US Patent
Affinity DataIC50: 0.800nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University Of Washington Through Its Center For
US Patent
University Of Washington Through Its Center For
US Patent
Affinity DataIC50: 0.800nMAssay Description:Most known kinase inhibitors bind in the ATP-binding pocket of the active site19,20. These inhibitors exploit many of the same hydrophobic contacts a...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University Of Washington Through Its Center For
US Patent
University Of Washington Through Its Center For
US Patent
Affinity DataIC50: 0.800nMAssay Description:Inhibitors were evaluated in triplicate in eight-point dilutions (3-fold dilutions) during the enzymatic reactions. TgCDPK1 enzymatic inhibition was ...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University Of Washington Through Its Center For
US Patent
University Of Washington Through Its Center For
US Patent
Affinity DataIC50: 0.800nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University Of Washington Through Its Center For
US Patent
University Of Washington Through Its Center For
US Patent
Affinity DataIC50: 0.900nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University Of Washington Through Its Center For
US Patent
University Of Washington Through Its Center For
US Patent
Affinity DataIC50: 0.900nMAssay Description:Most known kinase inhibitors bind in the ATP-binding pocket of the active site19,20. These inhibitors exploit many of the same hydrophobic contacts a...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University Of Washington Through Its Center For
US Patent
University Of Washington Through Its Center For
US Patent
Affinity DataIC50: 0.900nMAssay Description:Inhibitors were evaluated in triplicate in eight-point dilutions (3-fold dilutions) during the enzymatic reactions. TgCDPK1 enzymatic inhibition was ...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University Of Washington Through Its Center For
US Patent
University Of Washington Through Its Center For
US Patent
Affinity DataIC50: 0.900nMAssay Description:Inhibition of recombinant Toxoplasma gondii CDPK1 using Biotin-C6-PLARTLSVAGLPGKK as substrate after 90 mins in presence of ATP by luciferase reporte...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University Of Washington Through Its Center For
US Patent
University Of Washington Through Its Center For
US Patent
Affinity DataIC50: 1nMAssay Description:Inhibitors were evaluated in triplicate in eight-point dilutions (3-fold dilutions) during the enzymatic reactions. TgCDPK1 enzymatic inhibition was ...More data for this Ligand-Target Pair