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Found 11 Enz. Inhib. hit(s) with Target = 'NADPH--cytochrome P450 reductase'
TargetNADPH--cytochrome P450 reductase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50236853(CHEMBL4094677)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibitory concentration required for antagonistic activity at Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH--cytochrome P450 reductase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50236859(CHEMBL4086536)
Affinity DataIC50:  9.00E+3nMAssay Description:Substrate activity at CPR in human L02 cells assessed as CPR-mediated one-electron reduction of compound by measuring cell growth inhibition treated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH--cytochrome P450 reductase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM81348(β-Lapachone (A3) | Beta lapachone | R115 (Rea...)
Affinity DataIC50:  1.10E+4nMAssay Description:Substrate activity at CPR in human L02 cells assessed as CPR-mediated one-electron reduction of compound by measuring cell growth inhibition treated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH--cytochrome P450 reductase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50236854(CHEMBL4074173)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibitory concentration required for antagonistic activity at Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH--cytochrome P450 reductase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50236863(CHEMBL3398294)
Affinity DataIC50:  1.90E+4nMAssay Description:Substrate activity at CPR in human L02 cells assessed as CPR-mediated one-electron reduction of compound by measuring cell growth inhibition treated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH--cytochrome P450 reductase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50236858(CHEMBL4098063)
Affinity DataIC50:  1.90E+4nMAssay Description:Functional potency measured as intracellular calcium elevation in Hek-293 cells expressing hGHSR1aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH--cytochrome P450 reductase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50236857(CHEMBL4080037)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibitory concentration required for antagonistic activity at Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH--cytochrome P450 reductase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50236860(CHEMBL4065098)
Affinity DataIC50:  2.50E+4nMAssay Description:Functional potency measured as intracellular calcium elevation in Hek-293 cells expressing hGHSR1aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH--cytochrome P450 reductase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50236861(CHEMBL3398292)
Affinity DataIC50:  3.00E+4nMAssay Description:Substrate activity at CPR in human L02 cells assessed as CPR-mediated one-electron reduction of compound by measuring cell growth inhibition treated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH--cytochrome P450 reductase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50236862(CHEMBL3398293)
Affinity DataIC50:  3.20E+4nMAssay Description:Substrate activity at CPR in human L02 cells assessed as CPR-mediated one-electron reduction of compound by measuring cell growth inhibition treated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH--cytochrome P450 reductase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50236855(CHEMBL4102425)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibitory concentration required for antagonistic activity at Metabotropic glutamate receptor 2; Maximum inhibition reached only 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed