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Found 18 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor [1-999,L858R]'
TargetEpidermal growth factor receptor [1-999,L858R](Homo sapiens (Human))
Xuanzhu Pharma

US Patent
LigandPNGBDBM391743(N-(3-((2-((2-methoxy-4-(4-morpholinopiperidin-1-yl...)
Affinity DataIC50:  11nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-999,L858R](Homo sapiens (Human))
Xuanzhu Pharma

US Patent
LigandPNGBDBM391742(N-(3-((2-((2-methoxy-4-(1-(methylsulfonyl)piperidi...)
Affinity DataIC50:  88nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [1-999,L858R](Homo sapiens (Human))
Xuanzhu Pharma

US Patent
LigandPNGBDBM31340(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Affinity DataKd:  1.10E+5nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEpidermal growth factor receptor [1-999,L858R](Homo sapiens (Human))
Xuanzhu Pharma

US Patent
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataKd:  1.20E+5nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEpidermal growth factor receptor [1-999,L858R](Homo sapiens (Human))
Xuanzhu Pharma

US Patent
LigandPNGBDBM31090((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...)
Affinity DataKd:  410nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEpidermal growth factor receptor [1-999,L858R](Homo sapiens (Human))
Xuanzhu Pharma

US Patent
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataKd:  970nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-999,L858R](Homo sapiens (Human))
Xuanzhu Pharma

US Patent
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataKd:  940nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-999,L858R](Homo sapiens (Human))
Xuanzhu Pharma

US Patent
LigandPNGBDBM5445(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Affinity DataKd:  2.80E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-999,L858R](Homo sapiens (Human))
Xuanzhu Pharma

US Patent
LigandPNGBDBM13535(4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin...)
Affinity DataKd:  4.00E+5nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEpidermal growth factor receptor [1-999,L858R](Homo sapiens (Human))
Xuanzhu Pharma

US Patent
LigandPNGBDBM31093(4-[[7-[2,6-bis(fluoranyl)phenyl]-9-chloranyl-5H-py...)
Affinity DataKd:  3.20E+6nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEpidermal growth factor receptor [1-999,L858R](Homo sapiens (Human))
Xuanzhu Pharma

US Patent
LigandPNGBDBM31094(PKC-412 | cid_24202429)
Affinity DataKd:  7.60E+5nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEpidermal growth factor receptor [1-999,L858R](Homo sapiens (Human))
Xuanzhu Pharma

US Patent
LigandPNGBDBM13531(4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridy...)
Affinity DataKd:  1.90E+6nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEpidermal growth factor receptor [1-999,L858R](Homo sapiens (Human))
Xuanzhu Pharma

US Patent
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)
Affinity DataKd:  1.90E+6nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEpidermal growth factor receptor [1-999,L858R](Homo sapiens (Human))
Xuanzhu Pharma

US Patent
LigandPNGBDBM31096(CHEMBL290084 | Staurosporine | cid_451705)
Affinity DataKd:  2.70E+5nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEpidermal growth factor receptor [1-999,L858R](Homo sapiens (Human))
Xuanzhu Pharma

US Patent
LigandPNGBDBM21(CHEMBL24828 | N-(4-bromo-2-fluorophenyl)-6-methoxy...)
Affinity DataKd:  8.70E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEpidermal growth factor receptor [1-999,L858R](Homo sapiens (Human))
Xuanzhu Pharma

US Patent
LigandPNGBDBM4779(CHEMBL31965 | CHEMBL545315 | CI-1033 | Canertinib ...)
Affinity DataKd:  240nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEpidermal growth factor receptor [1-999,L858R](Homo sapiens (Human))
Xuanzhu Pharma

US Patent
LigandPNGBDBM31085(1-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluorom...)
Affinity DataKd:  2.60E+6nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEpidermal growth factor receptor [1-999,L858R](Homo sapiens (Human))
Xuanzhu Pharma

US Patent
LigandPNGBDBM26300(2-{3-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}qu...)
Affinity DataKd:  9.80E+5nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay