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Found 6 Enz. Inhib. hit(s) with Target = 'Estradiol 17-beta-dehydrogenase 1'
TargetEstradiol 17-beta-dehydrogenase 1(Rattus norvegicus)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50515434(CHEMBL4518587)
Affinity DataIC50:  9nMAssay Description:Inhibition of recombinant rat 17beta-HSD1 expressed in HEK293 cells using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstradiol 17-beta-dehydrogenase 1(Rattus norvegicus)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50126972(CHEMBL3629586)
Affinity DataIC50:  80nMAssay Description:Inhibition of recombinant rat 17beta HSD1 expressed in HEK293 cells using unlabeled- and labelled [2,4,6,7-3H]-E1 as substrate incubated for 10 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstradiol 17-beta-dehydrogenase 1(Rattus norvegicus)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50126973(CHEMBL3629587)
Affinity DataIC50:  97nMAssay Description:Inhibition of recombinant rat 17beta HSD1 expressed in HEK293 cells using unlabeled- and labelled [2,4,6,7-3H]-E1 as substrate incubated for 10 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstradiol 17-beta-dehydrogenase 1(Rattus norvegicus)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50515436(CHEMBL4441313)
Affinity DataIC50:  350nMAssay Description:Inhibition of recombinant rat 17beta-HSD1 expressed in HEK293 cells using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstradiol 17-beta-dehydrogenase 1(Rattus norvegicus)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50515435(CHEMBL4513439)
Affinity DataIC50:  388nMAssay Description:Inhibition of recombinant rat 17beta-HSD1 expressed in HEK293 cells using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstradiol 17-beta-dehydrogenase 1(Rattus norvegicus)
Elexopharm

Curated by ChEMBL
LigandPNGBDBM50515432(CHEMBL4447938)
Affinity DataIC50:  1.33E+3nMAssay Description:Inhibition of recombinant rat 17beta-HSD1 expressed in HEK293 cells using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed