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Found 1908 Enz. Inhib. hit(s) with Target = 'Neuropeptide Y receptor type 5'
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417035(CHEMBL1257993)
Affinity DataKi:  0.0251nMAssay Description:Antagonist activity at human NPY Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417033(CHEMBL1258111)
Affinity DataKi:  0.0316nMAssay Description:Antagonist activity at human NPY Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417056(CHEMBL1258225)
Affinity DataKi:  0.0398nMAssay Description:Antagonist activity at human NPY Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417051(CHEMBL1258787)
Affinity DataKi:  0.0631nMAssay Description:Antagonist activity at human NPY Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417036(CHEMBL1257992)
Affinity DataKi:  0.0631nMAssay Description:Antagonist activity at human NPY Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417045(CHEMBL1258341)
Affinity DataKi:  0.0631nMAssay Description:Antagonist activity at human NPY Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417032(CHEMBL1258110)
Affinity DataKi:  0.0794nMAssay Description:Antagonist activity at human NPY Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417050(CHEMBL1258674)
Affinity DataKi:  0.100nMAssay Description:Antagonist activity at human NPY Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417046(CHEMBL1258453)
Affinity DataKi:  0.100nMAssay Description:Antagonist activity at human NPY Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417044(CHEMBL1258340)
Affinity DataKi:  0.100nMAssay Description:Antagonist activity at human NPY Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417042(CHEMBL1257636)
Affinity DataKi:  0.100nMAssay Description:Antagonist activity at human NPY Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417041(CHEMBL1257637)
Affinity DataKi:  0.126nMAssay Description:Antagonist activity at human NPY Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417039(CHEMBL1257761)
Affinity DataKi:  0.158nMAssay Description:Antagonist activity at human NPY Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417390(CHEMBL1289154)
Affinity DataKi:  0.158nMAssay Description:Antagonistic activity at human NPY Y5 receptor expressed in HEK293 cells assessed as inhibition of calcium level by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417054(CHEMBL1258673)
Affinity DataKi:  0.158nMAssay Description:Antagonist activity at human NPY Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417040(CHEMBL1257760)
Affinity DataKi:  0.158nMAssay Description:Antagonist activity at human NPY Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417048(CHEMBL1258562)
Affinity DataKi:  0.200nMAssay Description:Antagonist activity at human NPY Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417047(CHEMBL1258454)
Affinity DataKi:  0.200nMAssay Description:Antagonist activity at human NPY Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417407(CHEMBL1289153)
Affinity DataKi:  0.200nMAssay Description:Antagonistic activity at human NPY Y5 receptor expressed in HEK293 cells assessed as inhibition of calcium level by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Chicken)
Uppsala University

Curated by PDSP Ki Database
LigandPNGBDBM82276(L31,P34-NPY,human | NPY Leu31, Pro34, human, rat |...)
Affinity DataKi:  0.210nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Chicken)
Uppsala University

Curated by PDSP Ki Database
LigandPNGBDBM50089038(CGP 71683 | CGP-71683A | CHEMBL17645 | N-{[(1r,4r)...)
Affinity DataKi:  0.240nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM85680(PP [cPP(1-7), NPY(19-23), Ala31, Aib32, Gln34], hu...)
Affinity DataKi:  0.240nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417055(CHEMBL1258788)
Affinity DataKi:  0.251nMAssay Description:Antagonist activity at human NPY Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Chicken)
Uppsala University

Curated by PDSP Ki Database
LigandPNGBDBM50005530(CHEMBL267633 | D-Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-G...)
Affinity DataKi:  0.280nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50353148(CHEMBL1829320)
Affinity DataKi:  0.300nMAssay Description:Displacement of [125I]peptide YY from human NPY5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50379608(CHEMBL2013020)
Affinity DataKi:  0.300nMAssay Description:Displacement of [125I]peptide YY from human NPY5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50128931(CHEMBL61880 | N-(9-Isobutyl-9H-carbazol-3-yl)-3-py...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using 125[I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Chicken)
Uppsala University

Curated by PDSP Ki Database
LigandPNGBDBM84998(NPY 3-36, porcine)
Affinity DataKi:  0.310nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417405(CHEMBL1289267)
Affinity DataKi:  0.316nMAssay Description:Antagonistic activity at human NPY Y5 receptor expressed in HEK293 cells assessed as inhibition of calcium level by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417052(CHEMBL1258907)
Affinity DataKi:  0.316nMAssay Description:Antagonist activity at human NPY Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417387(CHEMBL1289386)
Affinity DataKi:  0.316nMAssay Description:Antagonistic activity at human NPY Y5 receptor expressed in HEK293 cells assessed as inhibition of calcium level by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417406(CHEMBL1290037)
Affinity DataKi:  0.316nMAssay Description:Antagonistic activity at human NPY Y5 receptor expressed in HEK293 cells assessed as inhibition of calcium level by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417034(CHEMBL1258224)
Affinity DataKi:  0.316nMAssay Description:Antagonist activity at human NPY Y5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Chicken)
Uppsala University

Curated by PDSP Ki Database
LigandPNGBDBM82287(NPY2-36 | NPY2-36, human | NPY2-36, porcine)
Affinity DataKi:  0.350nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417404(CHEMBL1289609)
Affinity DataKi:  0.398nMAssay Description:Antagonistic activity at human NPY Y5 receptor expressed in HEK293 cells assessed as inhibition of calcium level by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416448(CHEMBL1209159)
Affinity DataKi:  0.398nMAssay Description:Antagonist activity at human NPY Y5 receptor expressed in HEK293 cells assessed as inhibition of calcium level by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50466538(CHEMBL4284905)
Affinity DataKi:  0.398nMAssay Description:Displacement of [125I]-PYY(1 to 36 residues) from human Y5R expressed in HEK293 cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50373621(CHEMBL403414)
Affinity DataKi:  0.400nMAssay Description:Displacement of [125]PYY from human chimeric NPY Y5 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50466538(CHEMBL4284905)
Affinity DataKi:  0.400nMAssay Description:Displacement of [125I]-PYY(1 to 36 residues) from human Y5R expressed in HEK293 cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM82276(L31,P34-NPY,human | NPY Leu31, Pro34, human, rat |...)
Affinity DataKi:  0.470nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50091652(CHEMBL269503 | PYY | PYY, rat | Peptide YY(PYY)(YP...)
Affinity DataKi:  0.480nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Chicken)
Uppsala University

Curated by PDSP Ki Database
LigandPNGBDBM82286(CAS_59763-91-6 | PP, human | PP,SALMON)
Affinity DataKi:  0.480nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50015490(CHEMBL438945 | H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...)
Affinity DataKi:  0.490nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50015490(CHEMBL438945 | H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...)
Affinity DataKi:  0.5nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50466532(CHEMBL4281479)
Affinity DataKi:  0.5nMAssay Description:Displacement of [125I]-PYY(1 to 36 residues) from human Y5R expressed in HEK293 cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50379595(CHEMBL2013012)
Affinity DataKi:  0.5nMAssay Description:Displacement of [125I]peptide YY from human NPY5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50466532(CHEMBL4281479)
Affinity DataKi:  0.501nMAssay Description:Displacement of [125I]-PYY(1 to 36 residues) from human Y5R expressed in HEK293 cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM84999(PYY,[leu31,Pro34], human)
Affinity DataKi:  0.570nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50015490(CHEMBL438945 | H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...)
Affinity DataKi:  0.600nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50353151(CHEMBL1829323)
Affinity DataKi:  0.600nMAssay Description:Displacement of [125I]PYY from human NPY5 receptor expressed in thymidine kinase deficient mouse LM cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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