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Found 14 Enz. Inhib. hit(s) with Target = '1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2'
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50256873(CHEMBL475790 | N-(4-chlorophenyl)-7-nitro-1H-indol...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of recombinant phospholipase C gamma2 (unknown origin) expressed in baculovirus infected Sf9 cells using [3H]PIP2 by flashplate biochemica...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50256872(7-nitro-N-phenethyl-1H-indole-2-carboxamide | CHEM...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of recombinant phospholipase C gamma2 (unknown origin) expressed in baculovirus infected Sf9 cells using [3H]PIP2 by flashplate biochemica...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50256870(5-(3-chlorophenyl)-3-(5-(isoxazol-3-yl)thiophen-2-...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of recombinant phospholipase C gamma2 (unknown origin) expressed in baculovirus infected Sf9 cells using [3H]PIP2 by flashplate biochemica...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50256801(4-((5-oxo-2-phenyloxazol-4(5H)-ylidene)methyl)benz...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of recombinant phospholipase C gamma2 (unknown origin) expressed in baculovirus infected Sf9 cells using [3H]PIP2 by flashplate biochemica...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50256871(5-(5-nitrothiophen-3-yl)-3-(pyridin-2-yl)-1,2,4-ox...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of recombinant phospholipase C gamma2 (unknown origin) expressed in baculovirus infected Sf9 cells using [3H]PIP2 by flashplate biochemica...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50256803(4-chloro-N-(4-oxo-4H-benzo[d][1,3]thiazin-2-yl)ben...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of recombinant phospholipase C gamma2 (unknown origin) expressed in baculovirus infected Sf9 cells using [3H]PIP2 by flashplate biochemica...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50256804(3-(2,2-dimethylchroman-6-yl)-1-(4-methoxyphenylsul...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of recombinant phospholipase C gamma2 (unknown origin) expressed in baculovirus infected Sf9 cells using [3H]PIP2 by flashplate biochemica...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50256875(6-(4-methoxyphenyl)-3-phenylthieno[2,3-e][1,2,4]tr...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of recombinant phospholipase C gamma2 (unknown origin) expressed in baculovirus infected Sf9 cells using [3H]PIP2 by flashplate biochemica...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50256874(CHEMBL475466 | N-(benzo[d]thiazol-2-yl)-5-methoxy-...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of recombinant phospholipase C gamma2 (unknown origin) expressed in baculovirus infected Sf9 cells using [3H]PIP2 by flashplate biochemica...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50066433(CHEMBL112884 | Hexadecanoic acid (R)-2-[(3-fluoro-...)
Affinity DataIC50:  8.00E+3nMAssay Description:In vitro inhibitory activity against bovine Phosphoinositide specific phospholipase C (PI-PLC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50256805(1-(2-Chloro-benzoyl)-3-(1,1-dioxo-1H-1lambda*6*-be...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of recombinant phospholipase C gamma2 (unknown origin) expressed in baculovirus infected Sf9 cells using [3H]PIP2 by flashplate biochemica...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50066431(((S)-3-Methoxy-4-octadecyloxy-butyl)-phosphonic ac...)
Affinity DataIC50:  1.00E+4nMAssay Description:In vitro inhibitory activity against bovine Phosphoinositide specific phospholipase C (PI-PLC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50256819(2-(4-nitrophenyl)-4-(thiophen-2-ylmethylene)oxazol...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of recombinant phospholipase C gamma2 (unknown origin) expressed in baculovirus infected Sf9 cells using [3H]PIP2 by flashplate biochemica...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50451248(CHEMBL2368948)
Affinity DataIC50:  1.99E+4nMAssay Description:In vitro inhibitory activity against bovine Phosphoinositide specific phospholipase C (PI-PLC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed