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Found 6 Enz. Inhib. hit(s) with Target = 'Potassium channel subfamily K member 18'
TargetPotassium channel subfamily K member 18(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50017662(2-(Diethylamino)-2',6'-acetoxylidide | 2-(Diethyla...)
Affinity DataIC50: >1.00E+5nMAssay Description:Channel blocking activity at human TRESK channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 18(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)
Affinity DataEC50:  4.74E+5nMAssay Description:Activation of human TRESK channel expressed in HEK293 cells assessed as induction of channel current by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 18(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50197058(CHEMBL3970106)
Affinity DataEC50:  4.50E+4nMAssay Description:Activation of human TRESK channel relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 18(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)
Affinity DataEC50: >1.00E+5nMAssay Description:Activation of human TRESK channel relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 18(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50197061(CHEMBL3965023)
Affinity DataEC50:  1.88E+4nMAssay Description:Activation of human TRESK channel expressed in HEK293 cells assessed as induction of channel current by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 18(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50197060(CHEMBL1417584)
Affinity DataEC50:  6.00E+3nMAssay Description:Activation of human TRESK channel relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed