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Found 198 Enz. Inhib. hit(s) with Target = 'Replication protein A 70 kDa DNA-binding subunit'
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM461292(US10774063, Compound NG-01-24)
Affinity DataIC50:  7.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM461287(US10774063, Compound NG-01-25 | US10774063, Compou...)
Affinity DataIC50:  1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM260646(US9533969, TDRL-505)
Affinity DataIC50:  1.29E+4nMAssay Description:Small molecule inhibitors were obtained from ChemDiv and resuspended in DMSO. Compound TDLR-505 was independently synthesized and structure confirmed...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM461289(US10774063, Compound TDRL-652)
Affinity DataIC50:  1.50E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM461287(US10774063, Compound NG-01-25 | US10774063, Compou...)
Affinity DataIC50:  1.80E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM61188(4-[5-(4-methylphenyl)-3-[3-(4-methylphenyl)-1-phen...)
Affinity DataIC50:  2.03E+4nMAssay Description:Small molecule inhibitors were obtained from ChemDiv and resuspended in DMSO. Compound TDLR-505 was independently synthesized and structure confirmed...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM461270(US10774063, Compound TDRL-505 | US10774063, Compou...)
Affinity DataIC50:  2.50E+4nMAssay Description:EMSA reactions (20 μL) were performed with 50 nM fl-RPA and 2.5 nM 5′[32P]-labeled 34-base DNA in buffer containing 20 mM HEPES (pH 7.0), ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM461282(US10774063, Compound TDRL-543)
Affinity DataIC50:  2.50E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM461288(US10774063, Compound TDRL-557)
Affinity DataIC50:  3.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM461285(US10774063, Compound TDRL-534)
Affinity DataIC50:  3.50E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM461270(US10774063, Compound TDRL-505 | US10774063, Compou...)
Affinity DataIC50:  3.80E+4nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM461286(US10774063, Compound TDRL-556)
Affinity DataIC50:  4.30E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM461280(US10774063, Compound TDRL-533)
Affinity DataIC50: >5.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM260649(US9533969, TDRL-522)
Affinity DataIC50:  5.61E+4nMAssay Description:Small molecule inhibitors were obtained from ChemDiv and resuspended in DMSO. Compound TDLR-505 was independently synthesized and structure confirmed...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM461276(US10774063, Compound j)
Affinity DataIC50:  6.00E+4nMAssay Description:EMSA reactions (20 μL) were performed with 50 nM fl-RPA and 2.5 nM 5′[32P]-labeled 34-base DNA in buffer containing 20 mM HEPES (pH 7.0), ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM260648(US9533969, TDRL-521)
Affinity DataIC50:  7.17E+4nMAssay Description:Small molecule inhibitors were obtained from ChemDiv and resuspended in DMSO. Compound TDLR-505 was independently synthesized and structure confirmed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM461272(US10774063, Compound f)
Affinity DataIC50:  7.50E+4nMAssay Description:EMSA reactions (20 μL) were performed with 50 nM fl-RPA and 2.5 nM 5′[32P]-labeled 34-base DNA in buffer containing 20 mM HEPES (pH 7.0), ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM461290(US10774063, Compound NG-01-02)
Affinity DataIC50:  7.55E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM461271(US10774063, Compound e)
Affinity DataIC50:  8.00E+4nMAssay Description:EMSA reactions (20 μL) were performed with 50 nM fl-RPA and 2.5 nM 5′[32P]-labeled 34-base DNA in buffer containing 20 mM HEPES (pH 7.0), ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM461281(US10774063, Compound TDRL-540)
Affinity DataIC50: >1.00E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM461283(US10774063, Compound TDRL-539)
Affinity DataIC50: >1.00E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM461269(US10774063, Compound c)
Affinity DataIC50: >1.00E+5nMAssay Description:EMSA reactions (20 μL) were performed with 50 nM fl-RPA and 2.5 nM 5′[32P]-labeled 34-base DNA in buffer containing 20 mM HEPES (pH 7.0), ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM461259(US10774063, Compound b)
Affinity DataIC50: >1.00E+5nMAssay Description:EMSA reactions (20 μL) were performed with 50 nM fl-RPA and 2.5 nM 5′[32P]-labeled 34-base DNA in buffer containing 20 mM HEPES (pH 7.0), ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM461255(US10774063, Compound a)
Affinity DataIC50: >1.00E+5nMAssay Description:EMSA reactions (20 μL) were performed with 50 nM fl-RPA and 2.5 nM 5′[32P]-labeled 34-base DNA in buffer containing 20 mM HEPES (pH 7.0), ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM260650(US9533969, TDRL-523)
Affinity DataIC50: >1.00E+5nMAssay Description:Small molecule inhibitors were obtained from ChemDiv and resuspended in DMSO. Compound TDLR-505 was independently synthesized and structure confirmed...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM461291(US10774063, Compound NG-01-04)
Affinity DataIC50: >1.00E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM260647(US9533969, TDRL-518)
Affinity DataIC50: >1.00E+5nMAssay Description:Small molecule inhibitors were obtained from ChemDiv and resuspended in DMSO. Compound TDLR-505 was independently synthesized and structure confirmed...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM461273(US10774063, Compound g)
Affinity DataIC50: >1.00E+5nMAssay Description:EMSA reactions (20 μL) were performed with 50 nM fl-RPA and 2.5 nM 5′[32P]-labeled 34-base DNA in buffer containing 20 mM HEPES (pH 7.0), ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM461278(US10774063, Compound l)
Affinity DataIC50: >1.00E+5nMAssay Description:EMSA reactions (20 μL) were performed with 50 nM fl-RPA and 2.5 nM 5′[32P]-labeled 34-base DNA in buffer containing 20 mM HEPES (pH 7.0), ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM461275(US10774063, Compound i)
Affinity DataIC50: >1.00E+5nMAssay Description:EMSA reactions (20 μL) were performed with 50 nM fl-RPA and 2.5 nM 5′[32P]-labeled 34-base DNA in buffer containing 20 mM HEPES (pH 7.0), ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM461274(US10774063, Compound h)
Affinity DataIC50: >1.00E+5nMAssay Description:EMSA reactions (20 μL) were performed with 50 nM fl-RPA and 2.5 nM 5′[32P]-labeled 34-base DNA in buffer containing 20 mM HEPES (pH 7.0), ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM461277(US10774063, Compound k)
Affinity DataIC50: >1.00E+5nMAssay Description:EMSA reactions (20 μL) were performed with 50 nM fl-RPA and 2.5 nM 5′[32P]-labeled 34-base DNA in buffer containing 20 mM HEPES (pH 7.0), ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50437275(CHEMBL2407473)
Affinity DataKd:  1.10E+4nMAssay Description:Binding affinity to human RPA70N assessed as inhibition of interaction with FITC-Ahx-DFTADDLEELDTLAS-NH2 after 1 hr by fluorescence polarization anis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50437276(CHEMBL2407470)
Affinity DataKd:  1.10E+4nMAssay Description:Binding affinity to human RPA70N assessed as inhibition of interaction with FITC-Ahx-DFTADDLEELDTLAS-NH2 after 1 hr by fluorescence polarization anis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50437277(CHEMBL2407466)
Affinity DataKd: >2.50E+5nMAssay Description:Binding affinity to human RPA70N assessed as inhibition of interaction with FITC-Ahx-DFTADDLEELDTLAS-NH2 after 1 hr by fluorescence polarization anis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50437278(CHEMBL2407453)
Affinity DataKd: >2.50E+5nMAssay Description:Binding affinity to human RPA70N assessed as inhibition of interaction with FITC-Ahx-DFTADDLEELDTLAS-NH2 after 1 hr by fluorescence polarization anis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50437279(CHEMBL2407448)
Affinity DataKd: >2.50E+5nMAssay Description:Binding affinity to human RPA70N assessed as inhibition of interaction with FITC-Ahx-DFTADDLEELDTLAS-NH2 after 1 hr by fluorescence polarization anis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50437280(CHEMBL2407447)
Affinity DataKd: >2.50E+5nMAssay Description:Binding affinity to human RPA70N assessed as inhibition of interaction with FITC-Ahx-DFTADDLEELDTLAS-NH2 after 1 hr by fluorescence polarization anis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50437281(CHEMBL2407446)
Affinity DataKd: >2.50E+5nMAssay Description:Binding affinity to human RPA70N assessed as inhibition of interaction with FITC-Ahx-DFTADDLEELDTLAS-NH2 after 1 hr by fluorescence polarization anis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50437282(CHEMBL2407445)
Affinity DataKd: >2.50E+5nMAssay Description:Binding affinity to human RPA70N assessed as inhibition of interaction with FITC-Ahx-DFTADDLEELDTLAS-NH2 after 1 hr by fluorescence polarization anis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50437283(CHEMBL449442)
Affinity DataKd:  1.85E+6nMAssay Description:Binding affinity to human RPA70N assessed as inhibition of interaction with FITC-Ahx-DFTADDLEELDTLAS-NH2 after 1 hr by fluorescence polarization anis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50424782(CHEMBL1448105)
Affinity DataKd:  6.27E+5nMAssay Description:Binding affinity to human RPA70N assessed as inhibition of interaction with FITC-Ahx-DFTADDLEELDTLAS-NH2 after 1 hr by fluorescence polarization anis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50437284(CHEMBL2407482)
Affinity DataKd: >2.50E+5nMAssay Description:Binding affinity to human RPA70N assessed as inhibition of interaction with FITC-Ahx-DFTADDLEELDTLAS-NH2 after 1 hr by fluorescence polarization anis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50437285(CHEMBL2407481)
Affinity DataKd: >2.50E+5nMAssay Description:Binding affinity to human RPA70N assessed as inhibition of interaction with FITC-Ahx-DFTADDLEELDTLAS-NH2 after 1 hr by fluorescence polarization anis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50437286(CHEMBL2407480)
Affinity DataKd: >2.50E+5nMAssay Description:Binding affinity to human RPA70N assessed as inhibition of interaction with FITC-Ahx-DFTADDLEELDTLAS-NH2 after 1 hr by fluorescence polarization anis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50437287(CHEMBL2407479)
Affinity DataKd: >2.50E+5nMAssay Description:Binding affinity to human RPA70N assessed as inhibition of interaction with FITC-Ahx-DFTADDLEELDTLAS-NH2 after 1 hr by fluorescence polarization anis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50437288(CHEMBL2407478)
Affinity DataKd: >2.50E+5nMAssay Description:Binding affinity to human RPA70N assessed as inhibition of interaction with FITC-Ahx-DFTADDLEELDTLAS-NH2 after 1 hr by fluorescence polarization anis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50437289(CHEMBL2407477)
Affinity DataKd: >2.50E+5nMAssay Description:Binding affinity to human RPA70N assessed as inhibition of interaction with FITC-Ahx-DFTADDLEELDTLAS-NH2 after 1 hr by fluorescence polarization anis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50437290(CHEMBL2407476)
Affinity DataKd: >2.50E+5nMAssay Description:Binding affinity to human RPA70N assessed as inhibition of interaction with FITC-Ahx-DFTADDLEELDTLAS-NH2 after 1 hr by fluorescence polarization anis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplication protein A 70 kDa DNA-binding subunit(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50437291(CHEMBL2407475)
Affinity DataKd: >2.50E+5nMAssay Description:Binding affinity to human RPA70N assessed as inhibition of interaction with FITC-Ahx-DFTADDLEELDTLAS-NH2 after 1 hr by fluorescence polarization anis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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