TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
TargetSodium channel protein type 1 subunit alpha(Rattus norvegicus)
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
TargetSodium channel protein type 1 subunit alpha(Rattus norvegicus)
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
TargetSodium channel protein type 1 subunit alpha(Rattus norvegicus)
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
TargetSodium channel protein type 1 subunit alpha(Rattus norvegicus)
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
TargetSodium channel protein type 1 subunit alpha(Rattus norvegicus)
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human Nav1.1 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 4.10nMAssay Description:Inhibition of human Nav1.1 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 6nMAssay Description:Inhibition of human Nav1.1 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 11nMAssay Description:Inhibition of full length human Nav1.1 expressed in HEK cells by whole cell voltage clamp analysisMore data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 11nMAssay Description:Inhibition of human Nav1.1 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 16nMAssay Description:Inhibition of human Nav1.1 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: <20nMAssay Description:Inhibition of human NaV1.1 channel by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: <30nMAssay Description:Inhibition of voltage-gated Na channel 1.1 (unknown origin)More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 31nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 37nMAssay Description:Inhibition of human Nav1.1 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 45nMAssay Description:Inhibition of inactivated state of recombinant human NaV1.1 expressed in HEK293 cell membranes coexpressing Nav beta1 subunit assessed as decrease in...More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 50nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 53nMAssay Description:Inhibition of inactivated state of recombinant human NaV1.1 expressed in HEK293 cell membranes coexpressing Nav beta1 subunit assessed as decrease in...More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 90nMAssay Description:Inhibition of human Nav1.1 by V1/2 protocol based analysisMore data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 112nMAssay Description:Inhibition of inactivated state of recombinant human NaV1.1 expressed in HEK293 cell membranes coexpressing Nav beta1 subunit assessed as decrease in...More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 112nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 114nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 133nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 142nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 147nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 159nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 182nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 202nMAssay Description:Inhibition of full length human Nav1.1 expressed in HEK cells by whole cell voltage clamp analysisMore data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 216nMAssay Description:Inhibition of human NaV1.1 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp metho...More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 245nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 245nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 260nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 277nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 283nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 301nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 303nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 309nMAssay Description:Inhibition of human Nav1.1 expressed in HEK cells by patch clamp electrophysiology methodMore data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 310nMAssay Description:Inhibition of human Nav1.1 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 314nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 332nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 364nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 388nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 400nMAssay Description:Inhibition of 10 Hz stimulated Nav1.1 (unknown origin) by manual patch clamp methodMore data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 420nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 476nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 494nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Sanofi-Synthelabo Recherche
Curated by PDSP Ki Database
Affinity DataIC50: 516nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair